The ruling, by Los Angeles Superior Court Judge Maren Nelson, reverses the $417 million verdict against J&J which was awarded to California resident Eva Echeverria in August 2017.
Echeverria was awarded $70 million in compensatory damages and $347 million in punitive damages on claims that J&J failed to adequately warn consumers about the cancer risks of its talc-based products.
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Attorneys for Echeverria said they plan to file an appeal immediately.
Currently, J&J states that there are some 4,800 pending lawsuits all alleging related claims of cancer stemming from the use of its talc-powder products. Those cases are being heard in California and Missouri.
Last week, a $72 million talc powder jury verdict against J&J talc powder was thrown out by a Missouri appellate court.