Tampa, FLCrestor is only one of a handful of statin drugs that represent the mother lode for those pharmaceutical companies with a product serving that market. Aging Baby Boomers, coupled with the prevailing wisdom that statin use lowers the bad cholesterol thought to promote heart attacks, strokes and other cardiovascular events has combined to make statins one of the most-prescribed medications in the world. Crestor (rosuvastatin) is part of that group. And there is a basket of Crestor side effects ranging from the trivial, to life threatening.
The recent publication of a new book lends a fresh perspective on statins, a class that includes Crestor as a leading product in that class.
How Statin Drugs Really Lower Cholesterol (And Kill You One Cell At A Time) is a book penned by James B. Yoseph and Hannah Yoseph, MD, a retired GP. According to various reports the Florida authors have spent years researching their book, and have a few things to say about how statins, in their view and according to research available to them, actually reduce levels of so-called 'bad cholesterol' in the blood.
In a video published to You Tube (4/5/12), co-author James B. Yoseph explains to the host that statins such as Crestor interrupt the mechanism by which human cells—which die off on a regular basis and is perfectly normal—regenerate themselves.
"Some overcome the blockade," notes Yoseph," so the death is very slow." He also says that many of the aches, pains and overall fatigue generally chalked up to aging, may very well have been triggered by statins.
Statin use has been proven to lower levels of bad cholesterol in the blood. And Yoseph says that it is true, the bad cholesterol leaves the blood. However, according to the author the cholesterol does not leave the body.
"[The cholesterol] leaves the blood and comes into the cell, and actually contributes to cell death—it's called 'apoptoisis'," Yoseph notes. "These drugs kill you one cell at a time, your cells which normally clone themselves and replace themselves cannot do that under the influence of statins."
According to Yoseph, the statins block the mevalonate pathway that is integral to human cell rejuvenation. Statins, says Yoseph, is akin to poison. Prescribed poison.
More common Crestor side effects include random aches and pains, especially in the muscles and joints. A more serious Crestor adverse reaction is Crestor rhabdoymylosis, which is characterized by the breakdown of muscle tissue, and the absorption of that muscle tissue into the bloodstream. It has proven fatal in some.
Crestor diabetes is another of the more serious adverse reactions.
But of all the Crestor issues listed, there is no mention of the science, suggested in the Yoseph book, that statins like Crestor are capable of actually interrupting the natural process of sustained life borne through the rejuvenation of human cells to replace those cells, which have naturally died off.
The process constitutes a slow death that may not otherwise happen were it not for the introduction of a statin, such as Crestor, in the body.
Cholesterol can be largely controlled through changes in diet and regular exercise. For those with high levels of so-called bad cholesterol, lowering cholesterol levels in an effort to prevent buildup of plaque in the arteries through the employment of a statin is seen as beneficial and necessary for serious cholesterol cases.
However, the role of cholesterol in otherwise healthy individuals continues to be the basis for much debate. And known Crestor issues aside, most statin patients have little clue as to just how statins work, and what the overall cost is to human health.
According to the mandate of the US Food and Drug Administration (FDA), a medication is considered useful and worthy of approval if the benefits for the intended community of patients outweigh the risk. One can imagine, then, that for many in the health industry the capacity to control bad cholesterol in an effort to prevent heart attacks and other cardiovascular issues is a benefit when weighed against the prospect, as alleged in the Yoseph book, of dying just a little bit quicker due to cell death.
Doctors appear to be turning to statins in ever-increasing numbers. And a press release posted to PRWeb (5/28/12) announcing a promotional agreement between the authors and a consulting service backs up that claim, with "hundreds of millions" of prescriptions for statins already written.
Those will only continue as the manufacturers of statins source new and lucrative markets for medications such as Crestor. "Statin Drugs are the most profitable prescription drugs in history," notes the release.
One wonders if such revelations contained in the book, will foster yet another Crestor lawsuit by disgruntled plaintiffs unhappy with getting more than they bargained for.
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