Fluoroquinolones like Cipro have been used in the US since the 1980s, with the intention of treating a variety of bacterial infections, according to the news source. In July 2008, the FDA decided to issue a black box warning in response to increased reports about the risk of tendinopathy and rupture.
According to the news source, fluoroquinolone antimicrobials are preferred by doctors and physicians because of their tolerability and bioavailability. They are also associated with a number of risks in addition to tendinopathy, however, including vomiting, headache and dizziness.
While less common, some serious side effects in addition to tendon rupture include hypersensitivity, dysglycemia and certain adverse cardiovascular effects.
According to the National Center for Biotechnology Information, in addition to treating bacterial infections, Cipro can also be used to treat patients who have been exposed to anthrax germs in the air.