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Patients who take Enbrel to treat certain types of arthritis may not be aware of the severity of Enbrel side effects they could be exposed to. These side effects include the risk of serious fungal infection and a risk of tuberculosis. Furthermore, the FDA is investigating a possible link between Enbrel and other drugs in its class, including Humira and Remicade, and the development of cancer in children and young adults.

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Enbrel Side Effects

In November 2008, the maker of the Enbrel drug (known generically as etanercept) was required by the FDA to strengthen the drug's warnings about the risk of Enbrel side effects. Specifically, the label was updated to include a strengthened warning about the risk to some patients of developing opportunistic fungal infections while taking Enbrel.

Arthritis MedicationAlthough the warning label already included warnings about the risk of serious infections, the FDA noted in its Safety Alert that cases of histoplasmosis and other invasive fungal infections were not recognized consistently, resulting in a delay in treatment for the patient. According to an FDA news release (September 4, 2008), at least 21 reports of fungal infection were not treated immediately and, of those, 12 patients died.

Symptoms of a systemic fungal infection include persistent fever, weight loss, sweats, cough, fatigue and shortness of breath. Patients who are taking Enbrel and notice these symptoms should seek medical attention because they could be experiencing serious side effects of Enbrel.

Enbrel is a tumor necrosis factor alpha blocker (TNF blocker) and is used to suppress the patient's immune system. It is used to treat moderate to severe rheumatoid arthritis, moderate to severe polyarticular juvenile idiopathic arthritis (formerly called juvenile rheumatoid arthritis), psoriatic arthritis, ankylosing spondylitis and moderate to severe plaque psoriasis.

The FDA had previously announced on May 1, 2008 that Enbrel's warning label was being updated to include a boxed warning alerting patients to the risk of infections including bacterial sepsis and tuberculosis.

Meanwhile, the FDA is investigating a possible association between the use of Enbrel and the development of lymphoma and other cancers in children and young adults. According to an FDA report (June 4, 2008), the agency is investigating approximately 30 reports over a 10-year period of cancer in children and young adults who used TNF blockers. Among the children and young adults who took Enbrel, cancers that were reported include lymphoma, leukemia, melanoma and solid organ cancers. The FDA has asked the makers of the TNF blockers to provide information about all cases of cancer in children who use those medications.

Enbrel is manufactured by Immunex Corporation and is marketed by Amgen and Wyeth Pharmaceuticals.

Enbrel Legal Help

If you or a loved one has taken Enbrel and suffered from side effects, please click the link below to send your complaint to a lawyer who will evaluate your claim at no cost or obligation.

Last updated on Mar-31-11


ENBREL SIDE EFFECTS LEGAL ARTICLES AND INTERVIEWS

Enbrel Side Effects Could Include Infections
Enbrel Side Effects Could Include Infections Bethesda, MD: Enbrel side effects can have serious consequences on patients receiving the injection, including infections that affect the entire body or even tuberculosis, a severe infection of the lungs, according to the National Center for Biotechnology Information (NCBI) [READ MORE]

Virginia Man Files Lawsuit over Enbrel Side Effects
Virginia Man Files Lawsuit over Enbrel Side Effects Virginia Beach, VA: A Virginia man has filed a lawsuit claiming therapeutics company Amgen concealed Enbrel side effects, which allegedly led to his development of cancer, according to the Courthouse News Service [READ MORE]

Fact or Coincidence? Enbrel Users Continue to Wonder
Fact or Coincidence? Enbrel Users Continue to Wonder Midway, KY: While Enbrel has been off the radar of late, the tumor necrosis factor alpha blocker (TNF blocker) is still on the minds of people who have used Enbrel to combat Enbrel arthritis or plaque psoriasis—and who have wound up with more than they had bargained for [READ MORE]



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