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Patients who take Enbrel to treat certain types of arthritis may not be aware of the severity of Enbrel side effects they could be exposed to. These side effects include the risk of serious fungal infection and a risk of tuberculosis. Furthermore, the FDA is investigating a possible link between Enbrel and other drugs in its class, including Humira and Remicade, and the development of cancer in children and young adults.

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Enbrel Side Effects

In November 2008, the maker of the Enbrel drug (known generically as etanercept) was required by the FDA to strengthen the drug's warnings about the risk of Enbrel side effects. Specifically, the label was updated to include a strengthened warning about the risk to some patients of developing opportunistic fungal infections while taking Enbrel.

Arthritis MedicationAlthough the warning label already included warnings about the risk of serious infections, the FDA noted in its Safety Alert that cases of histoplasmosis and other invasive fungal infections were not recognized consistently, resulting in a delay in treatment for the patient. According to an FDA news release (September 4, 2008), at least 21 reports of fungal infection were not treated immediately and, of those, 12 patients died.

Symptoms of a systemic fungal infection include persistent fever, weight loss, sweats, cough, fatigue and shortness of breath. Patients who are taking Enbrel and notice these symptoms should seek medical attention because they could be experiencing serious side effects of Enbrel.

Enbrel is a tumor necrosis factor alpha blocker (TNF blocker) and is used to suppress the patient's immune system. It is used to treat moderate to severe rheumatoid arthritis, moderate to severe polyarticular juvenile idiopathic arthritis (formerly called juvenile rheumatoid arthritis), psoriatic arthritis, ankylosing spondylitis and moderate to severe plaque psoriasis.

The FDA had previously announced on May 1, 2008 that Enbrel's warning label was being updated to include a boxed warning alerting patients to the risk of infections including bacterial sepsis and tuberculosis.

Meanwhile, the FDA is investigating a possible association between the use of Enbrel and the development of lymphoma and other cancers in children and young adults. According to an FDA report (June 4, 2008), the agency is investigating approximately 30 reports over a 10-year period of cancer in children and young adults who used TNF blockers. Among the children and young adults who took Enbrel, cancers that were reported include lymphoma, leukemia, melanoma and solid organ cancers. The FDA has asked the makers of the TNF blockers to provide information about all cases of cancer in children who use those medications.

Enbrel is manufactured by Immunex Corporation and is marketed by Amgen and Wyeth Pharmaceuticals.

Enbrel Legal Help

If you or a loved one has taken Enbrel and suffered from side effects, please click the link below to send your complaint to a lawyer who will evaluate your claim at no cost or obligation.

Last updated on Oct-26-09

ENBREL SIDE EFFECTS LEGAL ARTICLES AND INTERVIEWS

Enbrel Side Effects Could Include Infections
Enbrel Side Effects Could Include Infections Bethesda, MD: Enbrel side effects can have serious consequences on patients receiving the injection, including infections that affect the entire body or even tuberculosis, a severe infection of the lungs, according to the National Center for Biotechnology Information (NCBI) [READ MORE]

Virginia Man Files Lawsuit over Enbrel Side Effects
Virginia Man Files Lawsuit over Enbrel Side Effects Virginia Beach, VA: A Virginia man has filed a lawsuit claiming therapeutics company Amgen concealed Enbrel side effects, which allegedly led to his development of cancer, according to the Courthouse News Service [READ MORE]

Fact or Coincidence? Enbrel Users Continue to Wonder
Fact or Coincidence? Enbrel Users Continue to Wonder Midway, KY: While Enbrel has been off the radar of late, the tumor necrosis factor alpha blocker (TNF blocker) is still on the minds of people who have used Enbrel to combat Enbrel arthritis or plaque psoriasis—and who have wound up with more than they had bargained for [READ MORE]



READER COMMENTS

Posted by
Florida
on
Nodules on my lungs, recent history of fluid on heart. Took Enbrel for four years. Been taken off of it in the last two months

Posted by
Anonymous
on
I had my first shot of Enbrel and had no issues the second shot I put in my leg and instantly had major heat on my chest. Felt like a hot plate was sitting on me.
My heart doctor said I had a minor heart attack. I told the prescribing doctor and she was surprised. I never tried it again.

Posted by
Georgia
on
Unpaid hospital bills due to frequent visits due to serious infections
I have also been hospitalized after starting Humira in 2007 for Acemic Colitis and the flare ups continue to the present day. I have also been diagnosed with a fungul infection that has to date gone untreated.

Posted by
California
on
my mother had been taking enbrel for a little while and started having a hard time breathing. she went to the hospital they sent her home on oxygen. she was home for a week then couldn't breath even on oxygen. she went back to the hospital then they said her lungs had stiffened up. she died 2 weeks later.

Posted by
Massachusetts
on
My husband had psoriasis and was given Enbrel. He was 40 years old and was in great health. After being on Enbrel for a short period of time, he suffered a major heart attack in 2007 and passed away. Two weeks prior to his heart attack, he was given an exercise stress test and we were told that he was in great health.

Posted by
West Virginia
on
White spots on brain determined from shots not strokes, short term memory loss, inability to work since January when side effects worsened,muscle weakness, inability to drive, daily headaches,inability to stay awake, psoriasis worsened, etc.

Posted by
Missouri
on
I am a 35 year old male who brushes and maintains my teeth, but no matter what I do my teeth have become fragile and shatter at a very alarming rate. I have done research online and read many testimonies regarding this unlisted side effect.

Posted by
South Carolina
on
Atrial fibrillation, degenerative arthritis in left foot, loss of hair, had to quit my job, recurring arrhythmia, extensive hospitalization (cardiac CCU) 3 months of rehabilitation, still ongoing recovery after 12 months.

Posted by
Ontario
on
Poor immune sysem, damaged lungs, liver and kidneys. He suffers severe joint pain because the doctors now have to limit the anti-inflamitory drugs.

Posted by
Ohio
on
The loss of my brother who lived with me.

Posted by
Indiana
on
Loss of all feeling mid torso and below, hands and fingers. Bank teller and professional bowler - cannot do my jobs. Cannot go up and down the stairs in our house. Spinal tap results not in yet. Medical bills mounting.

Posted by
Ohio
on
The loss of my brother who should not have died. It was a sudden and unexpected death.

Posted by
Florida
on
I have suffered tremendously due to my sisters death related to a diagnosis of breast cancer after taking enbrel for psoriasis.

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