Request Legal Help Now - Free

LAWSUITS NEWS & LEGAL INFORMATION

Crestor and Statins Seen to Lower Energy, Libido

. By
Washington, DCWith Baby Boomers continuing to creep through middle age and into retirement, statin drugs such as Crestor are becoming increasingly popular for the lowering of the so-called 'bad' cholesterol thought to contribute to heart attack and stroke. So long as such patients are not besieged by statins side effects, they are likely to remain on statins for a very long time. It represents a boom for drug manufacturers.

However, not everyone appears to do well on statins without debilitating side effects—and there are plenty of possibilities. Statin cardiomyopathy is one such adverse reaction that could be serious: an impact on the heart through a change to the structure of the heart muscle.

Statin Rhabdomyolysis is another that has been addressed in the past. Rhabdomyolysis is a rare, but serious condition typified by the breaking down of muscle tissue at the hands of the statin. The potential for such broken down muscle tissue to become absorbed into the bloodstream, together with serious consequences to the kidney, cannot be understated. Many have died from this rare occurrence.

And here's one you may not have heard before: a lowered libido. While statins and Rhabdomyolysis remains the rare but serious cousin to a fairly common byproduct of statins such as Crestor—muscle pain—there is one muscle in particular that has become problematic for a 45-year-old man recently prescribed Crestor.

The contributor to The People's Pharmacy, a syndicated medical advice column penned by the husband-and-wife team of Joe Graedon, M.S., and Teresa Graedon, Ph.D., describes himself as a physical training instructor with the US Army. Active at 45, he began taking Crestor only to find that statin drugs did more than lower his cholesterol…

It also proved to lower his libido. "My sex drive has totally disappeared," he writes in a column that appeared in the Spokesman Review of Spokane, Washington (6/5/12). "I am unable to maintain an erection and feel tired all the time. It has been causing me a great deal of stress and anguish. Is Crestor causing my erectile dysfunction and libido problems?"

The Graedons answered while there is no mention of a lower sex drive in the Crestor prescribing information, some sexual side effects have been reported in some statin drugs.

But they go one further…

"There is reason to believe that all statins may have a negative impact on sexual function by lowering testosterone levels." The columnists back up their observation by citing studies that appeared in the Journal of Sexual Medicine (April, 2010) and Drug Safety (July, 2009). The latter published French research that suggested statins had the potential to trigger, or worsen erectile dysfunction.

More recent research suggest that statin drugs such as Crestor may cause users to experience decreased energy, fatigue upon exertion or both—as well as muscle aches and pains typically experienced by some patients. In a research letter published in the Archives of Internal Medicine (6/11/12), authors Beatrice A. Golomb, MD, PhD; Marcella A. Evans, BS; Joel E. Dimsdale, MD; and Halbert L. White, PhD outlined their results of a randomized controlled clinical trial that showed fatigue and exercise intolerance inherent with using statins were significantly greater than those patients on a placebo.

While two statins other than Crestor were used for the study, the researchers noted that cholesterol reduction would be similar to statins such as Crestor (rosuvastatin) at 2.5-5mg, which is a relatively low dose.

"Side effects of statins generally rise with increasing dose, and these doses were modest by current standards," Golomb said about the statin drugs.

"Yet occurrence of this problem was not rare—even at these doses, and particularly in women. Energy is central to quality of life. It also predicts interest in activity." Golomb, associate professor of medicine at UC San Diego School of Medicine, described the results as "important findings."

As for the complete loss of libido by a relatively young man, a statin lawsuit would not be a surprise.

READ ABOUT STATINS LAWSUITS

Statins Legal Help

If you or a loved one have suffered losses in this case, please click the link below and your complaint will be sent to a drugs & medical lawyer who may evaluate your Statins claim at no cost or obligation.

READER COMMENTS

Posted by

on
Testosterone (along with other androgens) is a sterol, made in the body from cholesterol. I can easily believe that lowering your cholesterol would come with effects on these hormonal cascades. There is research saying statins lower T, but only by a little. Still, these results are always averages over many patients--if you are at one or other range of effect, the average will not describe your experience. Possibly a different statin would be better for you. On the other hand, there has been too little study of this issue, so advice is mostly guesswork right now. For example, researchers are not sure whether the beneficial cardio effects of statins are partially BECAUSE of their lowering effect on testosterone.
Right now we do not have enough info to choose wisely, but i can certainly understand why some men might feel that increased heart health is not so compelling a benefit if it means a longer life but without sex. Each body (and each sex life!) is different. monitor your own carefully--it is the best teacher.

Posted by

on
I have been taking 20mg of crestor for past few years. My sex drive is gone. I tried to reduce it to 10mg but my total cholesterol increased from 150 to 260. I feel for sure Crestor is causing libido problems. But I also take lisinopril for BP which does not help.

Posted by

on
I am 63 and due to a family history of heart disease and blood test results as well as being diabetic I was advised to take a statin. Initially Crestor was prescribed and I experienced no noticeable side effects for two motnhs. Then due to cost cutting I switched to the generic version called Rosucard (Rosuvastatin) two weeks ago. Not only has my libido disappeared but I have intermittent sleep; prompting to research further possible causes. Factoring recent changes I focused on the new statin. Needless to say I was surprised to find so much information indicating that the statin may be the culprit. Interestingly enough there is no mention of this side effect listed on the packaging. I plan on bringing the topic up on my next visit to the cardiologist to see what other alternatives there might be.

Posted by

on
I am 59 years old and was recently placed on Crestor (20mg daily), a Statin medication for high cholesterol. Now I am also on Cipralex, an anti depressant that has the side effect of causing E.D. and lowered libido. But with the occasional addition of Cialis and playing around with when and when not to take my anti depressant, I had managed to work through the negative side effects of E.D. and lowered libido and achieve some livable measure of "balance" in my life. But since I began taking Crestor, my sex drive is completely gone, even with employing the strategies I described to work through the side effects of the anti depressant. No where is this side effect mentioned, even in a cursory fashion in the producers literature or on their web site. My doctor made no mention of this side effect either. Had I known of this possible side effect, I might have argued with my doctor for a different solution. Now I have to decide between which to live with more: The possible life shortening effects of high cholesterol or a sexless life.

Posted by

on
My husband started using Lipitor years ago I was only about 40, he was 45, yes there has not been any sexual contact between us. I kept saying to him we don't have a normal relationship but he never investigated and I just saw a documentary on Netflix last night, now we know, they ruined our marriage. I am now 58. I felt rejected and he didn't give me an explanation why he didn't have interest in me, we became more like room mates. We have kids so we stayed together aspecialy during university years.

Posted by

on
Don’t like my anti-cholesterol dope… I’m back to being a “neutered” male. I tried a science project with the Red Yeast Rice but that didn't do anything for the cholesterol. My doctor changed me from Lipitor to Crestor and after about 2 weeks my sex drive was gone again.

On the statin, no sex drive.
Off the statin, sex drive is back.

I think I would rather block my arteries with cholesterol than to be a neutered male.

Posted by

on
I had been having issues with low libido and with recent blood tests, my total and free testosterone levels came out to be quite low. I was just started on Testosterone gel and Progesterone troches and have been on these for two weeks. Unfortunately, I had started taking Crestor 5 mg every day for past 4 weeks (started two weeks prior to starting Testosterone/Progesterone). My doctor had told me that I should see significant difference within couple weeks with Testosterone and/Progesterone .... but I haven't seen any changes ... so I believe the Crestor may have been causing this to happen by decreasing Testosterone (a known side effect of statins) .... so I am stopping Crestor as of today and see what happens with the Testosterone/Progesterone and not being on Crestor concurrently. I do feel aches and pains and general tiredness with Crestor.

I wanted to share this with others who might be having similar problems like me. With recent literature review and having personally seen quite few patients dealing with statin related side effects, I am beginning to believe statins are a big market push by pharmaceutical industry and the cardiologists are blindly following them. The cholesterol they are chasing is not necessarily the culprit. The cholesterol is needed for a lot of bodily functions especially in the formation of almost every hormone in the body. When we take statins to lower cholesterol, body produces cholesterol through the liver to compensate for cholesterol that is needed for necessary bodily functions including formation of certain hormones. So to counteract the liver response, we continue to increase statin dose with ongoing side effects and no real benefit. The brain itself is made of 40% cholesterol. I wonder if Alzheimer's may have to do anything with the cholesterol lowering agents.

Both this band wagon about going after the cholesterol and also going on a low fat diet have not decreased any incidence of the diseases allegedly related to this; and in fact both heart disease and diabetes are on the rise in US despite the crazy push on statins to lower cholesterol and low fat diets for prevention of Diabetes and obesity. I think a certain amount of fat is needed to absorb fat soluble vitamins such as vitamin D. By stripping fat completely out of the diet and depriving the body, the absorption of vitamin D and other fat soluble nutrients is affected ... no wonder we have new rising epidemic of low vitamin D in our country. Even though people are pushed to take vitamin D but because many of us are on low fat diets ... don not have enough fats needed to absorb the vitamin D. Also, many of the low fat type of diet/milk have added fructose and God knows what other chemicals that are then responsible for elevated sugar despite being on a low fat/low sugar diets. Fructose is the worse of all the added sugars for keeping the pleasant taste of diet products. I think we have just gone too far and must follow a balanced diet, activity level and exercise. I am a physician myself and am beginning to see the reality. Hope this will be helpful to others in general.

Posted by

on
I was put on Simivastatin 40mg in 2009. I had muscle pain and lethargy and general felt old. I quit taking them in 2011 and quit going to Dr.s. They don't help you, they push these slow kill pills. The first of June this year I was ushered into the ER with ischemic colitis. More concern was with my heart. What the tests revealed is I now have a heart murmur and a LEAKY HEART VALVE!. The heart is a muscle it is well known that statins cause muscle damage. You can't convince me that the statin use for 2 years is not responsible for this.

Posted by

on
My husband was put on rosuvastatin last year and we noticed a decrease in his libido and he struggled to maintain an erection he stopped taking them and they difference was amazing after speaking to pharmacist who told him he needs to start taking them again which he has done the dysfunction has returned worse than before.

Posted by

on
A finding new to me personally concerning Crestor is
the appearance of hematuria with Crestor use. The hematuria is microscopic with occasional passage of
clots of blood. This happened to me personally while on the drug after a yr. or more. It seems to me that the problem
is more widespread than previously know. I discontinued
the Crestor and after two weeks the hematuria which was 3plus is now barely 1 plus. I think that this may be caused by a nephritis occurring perhaps at the higher doses. I was on 40 mg. daily.

Posted by

on
I'm a married 39 yr. old male and have tried several statins to try to lower my LdL cholesterol level. It seems that I'm having great difficulty tolerating any statins. Two months ago, I was put on a 20 mg. tablet and I too have experienced muscle weakness and lack of labido since I've been placed on Crestor. I've noticed that the possibility of a decrease in libido is not mentioned in the package insert. I'm strongly considering opting out on taking these statins.

Posted by

on
I also have a loss of libido from Crestor, but is that a reason to file a lawsuit? Why not just stop taking the drug and try something else? Moron.

ADD YOUR COMMENT ON THIS STORY

Fields marked * are mandatory. Please read our comment guidelines before posting.

*Name:

Note: Your name will be published with your comment.

*Email Address:

Your email will only be used if a response is needed.
*Your Comment:

Are you the defendant or a subject matter expert on this topic with an opposing viewpoint? We'd love to hear your comments here as well, or if you'd like to contact us for an interview please submit your details here.


Click to learn more about LawyersandSettlements.com

Request Legal Help Now! - Free