Babies born with PPHN have trouble breathing outside the womb after they are born.
According to the 5/16/10 issue of the Daily Mail in the UK, PPHN affects about two babies in every 1,000 births. In concert with antidepressants such as Prozac, that ratio goes up to five births in every 1,000. New research carried out by the European Medicines Agency's Pharmacovigilance Working Party confirmed the link to PPHN and SSRI use.
In the MHRA's latest drug safety communiqué to health care professionals, the agency noted that "a review of data has suggested that the use of SSRIs in pregnancy, particularly in the later stages, may increase the risk of persistent pulmonary hypertension in the newborn."
An insert inside all packaging related to SSRI antidepressants spells out the concern for both the expectant mother and her doctor.
READ MORE PPHN AND PROZAC LEGAL NEWS
Antidepressant use remains a hotly debated subject. Limiting or stopping antidepressant use in an expectant mother can reduce the risk to the unborn child, but can increase the risk to the mother. At the same time, it has been suggested that a baby born to a woman in a constant state of emotional crisis while pregnant can also be negatively impacted in some fashion.
However, a baby born with PPHN triggered from SSRI antidepressant use by the mother can face a life-threatening situation outside the womb.