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Plavix Gets Black Box Warning

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The FDA has warned that Plavix may not work for some people, putting them at greater risk for heart attack and stroke. The blood-thinner (anti-clotting) drug will get a black box warning and doctors have been told to consider alternative medications--such as aspirin-- for patients who cannot process the drug.

According to a report from the FDA, some patients with a genetic variation cannot metabolize the drug—meaning their bodies don't effectively convert Plavix to its active form. An estimated 2 percent to 14 percent of the population are poor metabolizers of Plavix. Patients can determine if they don't respond to Plavix by taking a genetic test.

The $8-billion-a-year drug sold by Bristol-Myers Squibb and Sanofi-Aventis makes Plavix the second-best selling drug in the world.


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READER COMMENTS

Posted by

on
I will stop taking Plavix. I am bleeding from my stomach.I did not have a stroke.I still take a baby aspirin.
Millie

Posted by

on
If it's so dangerous, maybe it shouldn't be the second best selling drug in the world. Obviously.

Hopefully people will become more educated and learn there are plenty of natural ways to thin one's blood without resorting to expensive and side-effects-ridden pharmaceuticals.

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