Lupron is used for a variety of purposes. It is prescribed to children to treat early-onset puberty, to men who exhibit symptoms of prostate cancer in men, and to women with endometriosis, a condition in which the uterine lining grows outside the uterus. Lupron is also used widely off-label as a "down regulator" for women going through IVF treatment. Patients take Lupron in a single day dose in the form of daily shots. Lupron Depot is given in an extended release injection that lasts for 30 days.At least one expert believes Lupron should be pulled from the market. Dr. John L. Gueriguian, former medical officer with the US Food and Drug Administration (FDA), stated in a report for a pharmaceutical liability lawsuit on 3/19/08 that Lupron should not be used.
"After years of use of [Lupron] in a great number of patients, the evidence is clear that TAP [Takeda Abbott Pharmaceuticals] didn't study [Lupron] adequately before marketing," Gueriguian states in his report. "After its introduction into the marketplace, TAP did not perform enough long-term studies to detect potential long-term and irreversible side effects of [Lupron], which has been shown, through independent observations and studies, to be able to cause irreversible side effects and permanent severely disabling health problems. Lupron temporarily stops menstruation, but does not eradicate endometriosis for long-term. Lupron should only be limited to six injections for the initial treatment, and a retreatment should not exceed six injections. Lupron cannot be given more than twelve injections per lifetime."
He goes on to say that endometriosis can grow back after Lupron treatment ends. What's more, Lupron was used to treat endometriosis in females under the age of 18, despite the fact that the drug had only been tested on women over the age of 18 with endometriosis.
Dr. Gueriguian alleges that that TAP intentionally suppressed knowledge about the risks associated with Lupron, including bone density loss (leading to permanent disability in some cases), generalized pain, headaches, fluid retention, depression and immune and nervous system problems, including spinal fracture, convulsions and paralysis.
Drugs whose risks outweigh their benefits should be pulled from the market, the report concludes.
Lupron, manufactured originally by TAP and now by Abbott, resulted from a joint venture between Takeda Pharmaceuticals and Abbott. The companies subsequently split in 2008, leaving Abbott with the rights to Lupron.
According to ABC News in Las Vegas (ktnv.com, 10/30/09), TAP pleaded guilty in 2001 to criminal charges that it violated the Federal Prescription Drug Marketing Act. The pharmaceutical company agreed to pay $875 million to settle claims that it paid kickbacks to doctors to promote Lupron. Dr. Andrew Friedman admitted that he falsified and fabricated 80 percent of the data in leuprolide acetate (Lupron) research reports.
The FDA has received more than 12,000 reports of adverse events linked to Lupron, including more than 1,100 deaths.
READER COMMENTS
ymp
on
Jenny Garner
on
So like a fool, I continued. The bone pain was horrific and went on for at least a year after I discontinued Lupron. There were other side effects, too. I look at photographs of myself at the time and you can see that I just don’t feel good. I gained 70 pounds in 8 months and have kept every single pound of it since then. I tried everything but I’m stuck with this extra weight. Sure, I can starve myself but that isn’t sustainable. I am 5’8” and weighed 140-160 lbs. my entire adult life. I love to work out – played soccer, swam, ran 5K’s, etc. Try lugging around 70 extra lbs. It just doesn’t work. I still work out but it’s super sad compared to what I used to be able to do.
I also acquired an autoimmune disease which I blame fully on Lupron.
Christina Cornelius
on
marvin dixon
on
deadly.... do not take this drug. do not take this drug
this drug is a hormone supressor drug and fibroids and cancer
will always grow back.. always. . fibrosis lawsuits big coverups
big coverups. do not take this drug.. poison.. deadly. big coverup
suffering this drug ate up my entire female system... fibrosis to
tissues nerves everything lawsuits big time
tasha
on
Peggy
on
Nichoke
on
I wanted to thank all the people who posted their story. Endometriosis already makes you feel like a hypochondriac or a big baby. So you learn to always second guess yourself or let thing go, because your afraid others might see you the seem way.
Kendelle
on
jabooty
on
for a 4 month shot. My PSA was 55 when I started Lupron. When
I went in Nov. my PSA was 1.8, I told the urologist I was not taking any more Lupron. I was not diabetic before Lupron, In
December I was diagnosed with full blown diabetes and now
have to take insulin daily. I hoped since I stopped the Lupron
my diabetes will approve and I can stop the insulin.
Spt
on
Now I score 36th percentile. I can't do math, I can't read technical articles, I can't spot logical errors as I used to. My sleep is awful and my mood is dreadful despite starting Wellbutrin over a month ago. Didn't help.
Hot flashes are every 11 minutes, but I would take double that if Lupron hadn't made me into a moron.
Worst of all, I find that there is no survivorship benefit to Lupron. I've lost at least 6 months of whatever life I have remaining, probably a year. All for nothing.
Don
on
Claudia Arenas
on
Jacqualine
on
Tracy
on
I called the pharmaceutical company 10 years ago to ask about what studies they had done for long term use and was hung up on.
I believe my medical problems - joint pain, gastrointestinal, weight gain, broken bones, etc. are the results of being on the medication. I just wish that the doctors would have told me. I would have at least liked to have weighed my options.
gabe
on
Ray Smith
on
Monica
on
dave
on
Lizard
on
Amie
on
Miller M
on
Andrew
on
I've had three 3-month and one 6-month injections so far, and I accept the discomfort that comes with the drug.
I guess what I am saying is to not just lay back and complain when you could be doing things for yourself. I told the doctors that I'll go along with anything that will keep me above ground a while longer. And when the Lupron is no longer effective, I'll just go to plans A, B, C and take other medications.
I suspect that some of the symptoms described above could be better treated by consultation with a psychiatrist than by complaining about Lupron. Without it, I doubt that I'd be sitting here writing this. Thanks for reading.
Roy Mullins
on
Reading all these statements I know in my heart that this drug LUPRON is so very bad it should never be taken by anyone.
gabe
on
Cheryl
on
Thomas Barrett
on
night sweats hot flashes zero interest in sex fatigue loss of body hair and blurry vision
PSA dropped after radiation 45 treatments
hope to get off this soon
symptoms seem to get worse as I get more shots
Charlie Eskridge
on
Charlie Eskridge
I don't have any Testosterone but that was from the radiation
gabe
on
Reginald Sudds
on
Karon
on
Hospital for 4 days: 3 MRI's, EKG, Echocardiogram, blood work...all NORMAL. Discharged, diagnosis:possible vertigo
3 days later: same symptoms + neck pain & pounding headache and again stoke like blood pressure. Back to the hospital: blood pressure meds, Spinal Tap ....ALL NORMAL
no Lupus, MS, Lyme Disease, NOTHING
Only one difference in this healthy 25 year old >>LUPRON
None of these side effects were ever revealed and finally the doctor tells me this is rare only 1 in 1000 SERIOUSLY !! that is NOT RARE that is CHRONIC
The debilitating effects of this drug have been known to the medical field & they are still prescribing for personal financial gain
Mike
on
Espo
on
Margaret Chikamwase
on
The backache pain, pelvic pain and constipation has reduce
Meera
on
During the first month, I experienced hot flashes and noticed that my skin on my legs started to get scaly, which has never happened here in CA. I still got my period during the first month. I received a second Lupron injection, not thinking twice, and right around the time that my period was supposed to come, I felt a hot prickly sensation run throughout my body, and then a rash started to develop all over my body. OMG, its horrible. I went to 2 Urgent cares, and was given antibiotics which are supposedly contra-indicated, and then steroid cream, then a visit to my oncologist, who didn't even want to look at it, and said I need to see a dermatologist, and suggested I go to ER so I can get fast tracked to one. Meanwhile my rash is not getting better......its not spreading anymore, thankfully.
I was set to get a third injection and refused it. My Oncologist then decided that she is not able to fill out paperwork for my job to accomodate different hours. Why? Because I was doing holistic and refusing chemo, and all of their drugs except Lupron, until now.
I have since seen a Holistic Chinese doctor, who will be following me and treating both the rash and cancer. I have been doing a holistic regime since March 2016, and then included a cannabis protocol mid May, and recently shifting holistic regime to a Eastern medicine, and my tumors are shrinking.
My Chinese doc looked at my rash and said that I have poison in my system. Lupron is poison, period.
Whatever happened to doctors honoring their oath 'to do no harm'?
There should be a class action suit against the makers of Lupron, and the Doctors who prescribe it.
I am going fully holistic.
Stephanie Merck
on
Maria
on
Bridget
on
I was given Lupron for endometriosis for 6 months in 2001. My doctor told me it would only cause bone loss if taken for more than 6 months. He said I'd have TEMPORARY symptoms of menopause while taking it. He said Lupron had been shown to shrink/kill endometriosis, or at least get rid of the pain, sometimes permanently, and sometimes for several years before the disease returned. He said taking Lupron might keep me from having to have a hysterectomy. So I opted to try Lupron before resorting to surgery.
Of course I had all the symptoms of menopause while taking it. That was to be expected. As soon as the treatment was over, however, my endometriosis was worse than ever, and I was bleeding 6 weeks on, 1 week off. I had to have a hysterectomy anyway. Lupron was nothing more than a temporary band-aid with terrible, long-term health consequences.
It's been 15 years since I've taken it, and the side effects are not going away. New symptoms occur over time, and old symptoms get worse over time. I had no idea this drug was the cause of my mysterious health issues until I saw this website today.
*Weight Gain: I'm 4'11". I always weighed between 90-100 pounds before taking Lupron (even after having kids). I gained 60 pounds within a year after taking Lupron. I can't lose the weight unless I literally starve myself...which I'm assuming is why some people become anorexic. If I eat more than a half sandwich and a handful of veggies in a day, I gain weight. I started taking Phentermine last month to try to lose some weight. We'll see if it works.
*Memory Loss: I noticed this immediately after my first shot. I used to be known for my excellent memory and my sharp wit. Now I feel foggy-headed, I have a hard time retrieving words from memory while speaking simple sentences, I can't remember specific details, I get confused while trying to remember something, I can't remember names, important details. Phentermine helps with this.
*Fatigue: I used to be a ball of energy with a bubbly personality. Now I'm exhausted no matter how much sleep I get. I have a hard time getting out of bed. I want to take a nap 2 hours after getting up. Sometimes I have to take a nap before driving home from work. I take sublingual vitamin B-12, and vitamin B complex.
*Chronic Diarrhea: I never had this problem before. For the last 15 years, every morning I spend 2 hours in the bathroom before I can go to work. (Metamucil helps).
*Bone Loss: Excruciating pain in my lower back, sometimes my hips, and on really bad days all my bones ache throughout my body. Calcium, vitamin D, and bananas help.
*Vitamin D deficiency: I never had this problem before. I think this contributes to the diarrhea issue. I take 2 Viactive supplements a day.
*Migraines, including tooth pain and jaw pain that shoots up my head and down my neck: I take 2 aspirin, and 1 Tylenol with a cup of coffee.
*Gastritis, inflamed lower esophagus and inflamed voice box...but middle esophagus is mysteriously fine: I take probiotic or eat yogurt.
*Foot pain when I stand up. Tingly or itchy skin at times.
*Blurred Vision & light sensitivity.
*Hair Loss: My hair is about 1/3 as thick as it used to be. I have a nice little bald spot up in front. Luckily no one notices because I part my hair on the side. I can no longer part my hair in the middle. Also, no more bangs for me!
*Violent Chronic Dry Cough: This is debilitating. It's non-stop, 24 hours a day, 7 days a week. I can't sleep, can't eat, can't talk, lose my voice, rip muscles in my chest, throw out my neck which causes a migraine, gasp for air, and finally end up limp and lifeless after 2 days without medication. This started 2 years ago and hasn't gone away. They tested me for allergies, asthma, acid reflux, sarcoidosis, GERD, Crohns, IBS, H-Pylori, heavy metal poisoning, cancer, and on and on and on. Be careful of false asthma diagnoses. Now they're thinking it may be neurological which makes me think it may have something to do with Lupron. Does anyone else have this problem? Nothing works except a small dose of a narcotic. Tussienex works (half teaspoon, twice a day) but it makes me sleep 16 hours a day. Codeine cough syrup only works if I take a large dose, and it also makes me sleep 16 hours. 2.5mg of vicodin, 4 times a day works without making me feel like a zombie. Or 1mg a day of methadone will work. I'm hoping someone else has this problem too, and can help me find another way to fix it without having to take narcotics. This is actually why I'm trying so desperately to lose weight right now.
gabe
on
Quanda Smith
on
Mike O
on
He has taken every test but they find nothing wrong with any of his organs. For some reason he now has some fluid in his lungs & no lung specialist can tell us what it is. We went back to the cancer Dr that gave him the shot & he says that unfortunately there's nothing he can do about the symptoms. They should run their course & be over in 6-9 months. We are just praying that our dad will be alive by then. I can't believe doctors are giving people this poison & charging several thousands of dollars for each shot also.
Lisa
on
Steve
on
1) For the first 3 weeks, I began to wonder if they gave my the wrong shot. Then during the fourth week it started to hit me pretty hard. Following were my side effects.
2) Rapid loss in libido and sexual function starting week 4. Testicular shrinkage. Semen production dropped to zero. No sex for many months. I expected normal function to return about a month after the last shot timed out. It took four full months for the effects to even START to wear off. I expect it will be six months from the time-out before I get to 80-90% recovery from side effects.
3) Hot flashes typically 2 X per hour. In the end, I did not get a good night's sleep for a YEAR. The hot flashes were so frequent and intense, I was lucky to sleep for an hour at a time--and often less. Four months from the time out, the hot flashes are just starting to be manageable.
4) Impaired vision, which took months to recover from.
5) Joint pain, which still lingers.
6) Weight gain (+15 pounds) to a weight I have never even come close to in my entire life. Still struggling to get the "baby fat" off.
7) Increased cholesterol, from 160 to 237 in just a few months with the same or better diet.
8) Liver damage (GGT came in very high at 130), with no prior liver issues and very low alcohol use.
9) Notable breast growth.
10) Tiredness and general malaise; shortness of breath on modest exertion--even though I have always been in excellent physical condition and continued exercise during treatment.
11) Even with devoted exercise, my body responded weakly to maintenance of muscle mass, strength and endurance.
12) Notable reduction in facial hair growth, which has returned four months post, and body hair, which has not returned.
Overall, I'm not sure if the Lupron was a positive net contributor to curing my cancer, but I have no desire to ever take it again--for any reason.
Maya Domashitsky
on
Michael Pagliaro
on
Ken
on
Robin Worthington
on
Donna Bright
on
Additionally if you band together, look for an attorney using Martindale Hubbel. I am not an attorney, my daughter has just graduated law school. I would look into using a firm that specializes in these types of cases. I am very sorry for what this drug has done, God bless each of you.
Theresa
on
Jose A. DIaz
on
more than five years. Consequences:
Memory loss type AD them treated by neurologist .
Jose
Corky
on
My pain in my stomach started about a year ago.
It felt like I was having bad period cramps every day and I just thought I was going through menopause. I also was having heat flashes.
I decided to go to the the Doctor in April and they did an exam and ultrasound.
She said I had Adenomyosis a disease of the uterus.
I went to another doctor to get a second opinion she agreed and recommended a hysterectomy but I told her I wanted my own hormones and I'd like to keep my ovaries if possible so she planned on taking out my uterus and cervix.
I had the surgery April 29th.
It turns out I had Endometriosis, Adenomyosis, a cyst on one ovary, both ovaries were yellow and deformed, so they took out one of my ovaries my uterus and cervix.
6 weeks pass and I had pelvic pain, drainage and a fever so I went back and got an internal ultrasound and a CT scan she said I had an abscess on my vaginal cuff. She gave me medication for it.
July 29th I went back with more pain and had a new cyst and more endometriosis on my ovary.
July 29th she removed my ovary and the endometriosis that she could get to however she said she could see that it spread to other organs.
MY question is she wants me to start the shot Lepron!
For two days I have been researching it and the side affects sound horrible.
I'm not in pain right now.
I also read hormones feed the disease so I don't think I should go on Any Hormone Replacement for awhile.
What do you think?
Thanks C
Bri
on
lacreia white
on
Mia
on
Katie
on
For me, I had begun to experience some side effects around the end of the 4th month. Oiliness to the t-zone and scalp, some acne, and overall I gained 10 lbs. However, I had this incredible energy and as soon as I stopped taking Lupron I noticed an immense decrease in energy. My headaches are back as well.
I am kind of considering going back on it because I didn't feel like a zombie.
Sherri
on
Rit
on
Same story like everyone else. Daughter is diagnosed with Pre-Puberty and prescribed Lupron. Dr. assured no side affects. Reading all this i have a choice not to give this and take a chance with her growth or .....not sure...what to look for
Debra Lannon
on
Rebecca J.
on
Charles Pace
on
2014 after regular psa testing regular increases doctor did ultra sound, cystoscope, MRI and biopsy all neg.
2014 I then had bone scan showing several tumors two of the largest on spine
2014 Dec. started hormone therapy first month double dose of firmagon, then Lupron depot in 2015 Jan.
Lupron issues have been scary hot flashes, chills, itching have eased up some but cognitive issues have been upsetting memory, multitasking, concentration, decision making are debilitating.
I have not worked since Mar. It is rough stuff there is no way I could function anywhere near the level I should at all. Let alone personally do very little driving and only close by and rarely alone. Can not even do regular daily living things fast or correct. Memory horrible driving is difficult experience lots of bad cognitive issue I am scared. Not even good at paying bills correctly. Bad stuff and you read some things similar but doctors just say it's not the drug. So I am seeing a neurologist, phsiciatrist, and now more tests to determine what's causing my issues, because no one agrees it's the drugs. The costs of this is staggering. But I am 58 years old and need to work but can not function normal at all, if I was 65 I probably would not even complain about this but I am not. I believe there are many people older that do not even report this type of issue do to age and no need to work.
I have stage 4 bone mets cancer yes I am depressed but I was before starting this drug and the cognitive things started after that. Bad stuff but it is doing what they need it to but no one told me I could experience these issues.
chelsea
on
Belinda
on
Tommy
on
Jillian Crawford
on
I have endometriosis and they told me no warnings of this shot before they told me I was going to get it. They said there was nothing wrong with it and no reason not to take it. They also said my only options are lupron or pregnancy--I don't want kids, I'm in no situation for kids, I'm not healthy enough to carry a child, and there's a very low chance I'll conceive or if the baby will survive.
Now my back is in so much pain I can hardly move, there's so much sharp stabbing pain in my whole torso I sometimes get shortness of breath, and my fainting problem has only gotten worse.
They nurses said I was over-thinking this since I already get chronic pain from the endometriosis, but the pain was never like this on a regular basis. Even suffering from PID shortly after a laparoscopy never hurt this bad! Being fresh off the operating table didn't hurt anywhere nearly as bad as this!
Linda
on
Lorie parker
on
Kera
on
I have begun doing research on my own. I have recently sent for all of my medical files from all of the clinics and hospitals at which I've been treated. I'm trying to find anything that seems to be the beginning of it all. The other day on TV, someone mentioned Lupron and it was like light bulb went on. I immediately Googled "Long Term Side Effects from Lupron Depot" and the National Women's Health Network was the first article that came up, the article from the Womens Health Activist Newsletter, September/October 2008, by Susan K. Flinn, MA. I was in tears. Nothing has come this close to explaining what is wrong. I'm trying not to get my hopes up. But it was so nice to hear of others that were experiencing the same thing as me - not that I would wish this on my worst enemy, but it's still nice to not be alone.
Please could you send me any information you have acquired about these affects, any treatments that have been found to help, any sort of prognosis that has been discovered for people with type of severe reaction, and if there is any way of testing to verify that this is what is wrong. I would like to be able to bring as much literature into my medical team as possible.
I realize not everyone has the same reaction. I understand that since I have a majority of the symptoms, I may have a more severe reaction. My doctors have told me that I have a tendency to respond much worse than most people in anything that I contract.
Any help you can give me would be extremely appreciated. Thank you so much! If you could send it hard copy through the mail, I would greatly appreciate it. Please, can you help.
kera_mymail@yahoo.com
Shelley
on
Christine
on
Moriarty
on
I have not had endometriosis or early-onset puberty and thank God I have never taken Lupron. After reading the reports here, I believe that no one should ever take this drug. If a doctor has told you to take it, do not go along with his or her recommendation. You risk going through the agony that women have described in these reports. If you have taken it and suffered bad side-effects, you should get a lawyer and sue the manufacturer of the drug as well as the doctor who prescribed it for you. Please, please if you are suffering as described by so many above, help yourself and try to get a lawyer to represent you.
Liz
on
Tabby
on
I was given this drug as a means to stop unexplained reoccurring infections. It was an experiment and I was told this by the doctor. I had one shot and it has destroyed my health! Every side effect listed I have had. Two trips to the ER because I thought I was going to internally combust. I went from 120 lbs to 150lbs. I have horrible RA and bone spurs and Thyroid desiese. This medicine fried my Thyroid. If there is a future lawsuit I wantto be involved. I was lied to about this drug, not informed it was chemotherapy. I only found out by signing up to volunteer at a hospital that required I have certain vaccinations and could not administer them because I had a recent does of Lupron, chemotherapy, and it would kill me if the two shots were combined. Every Dr and Hospital should have to clearly tell their patient's this is chemotherapy and take this shot themselves.
This drug needs to be removed and the company who manufactures this ' killer drug' Lupron needs to start paying the medical bills of us who have suffered from its ramifications!
Tayler
on
Andrea
on
Everyone reacts differently, and perhaps there are some people that Lupron works wonders for, but I am not one of those people. I have done extensive research about Lupron and many women complain about the same symptoms that I experience. It has been such a terrible experience that I am looking for a class action law suit in Canada, because I believe Lupron has permanently damaged my joints and ruined the quality of my life.
The cost was $600 per injection, but fortunately covered by my benefits. After $7200 in Lupron injections, this is what I have been left to deal with.
I have since found a new GYN and when I explained to her how Lupron affected me she said that Lupron makes a lot of women feel crazy. If this is the case, why is it still prescribed to women with endometriosis or any other condition?
Please do your research before consenting to Lupron. If you do decide to do it, be sure that you are getting add-back therapy in the form of estrogen and progesterone, because when the Lupron kicks in and you are suddenly in menopause, it is HELL. Absolute and complete hell. Honestly, there are no adjectives to convey how absolutely horrible I felt on every possible level. To go from a relatively happy, upbeat person to severely depressed and contemplating ending my life was a horrible experience, and I really don't know how I made it through that terribly dark time.
I am not trying to scare anyone, I just want to share my experience that will hopefully spare someone else having to go through what I went through.
Good luck to all of you!
Lyn
on
I am preparing to have a laparoscopy myself in 2 weeks. I was diagnosed with stage 4 endo this year and, of all things, had a hernia repaired that the doctors say was caused by the endo. I have struggled with extremely heavy bleeding and cramps strong enough to bring me to my knees and render me bedridden for years, I am now 30.
My doctor has suggested administering the Lupron to shrink whatever lesions remain after surgery. In the past few days I have done extensive research about Lupron and, quite honestly, I am shocked and horrified by what I have read about this drug.
You are right, it is a chemo drug. I had been struggling to make a decision, trying to choose "the lesser of two evils." My ultimate belief is that this drug has too many potential long-term side effects. I do not believe that a chemotherapy-strength drug should be administered to a non-terminal patient.
I believe there are natural ways to lessen the pain, such as avoiding foods that can cause inflammation. Also, soy is known to contribute to excess estrogen, which I understand is one of the likely causes of endo. Glance at the ingredients list of most food sold in typical grocery stores and soy/protein is listed as an ingredient. It's sad that with so many women and girls suffering from this disease, there is so little understanding of the root cause(s).
Avoiding sugar is also a common suggestion I have come across for alleviating pain, although a definite challenge with so many processed/refined foods being sold.
My number one recommendation would be to build a strong support system of family and friends. March is national endometriosis awareness month I believe. Educate your loved ones and explain the facts about endo.
I have received tremendous support from a select few close family and friends. Without them, I could imagine this disease quickly wearing me down to the bone.
Best wishes to you
Fallon
on
Jeanne Walsh
on
Rachel
on
Melinda C
on
Linda
on
side effects are horrible, depression, anxiety, no appetite.
i only had one shot and i want this stuff out my system.
my anxiety is real bad.
Sara
on
Jennifer
on
Jennifer
cheryl
on
Well, my daughter is presently 13 years old. She got her period at 12 and is presently 5'4" tall. I am still hoping for a few more inches of height since her sister is 5"11" tall. However, we have some strange things going on at the present time. My daughter has been diagnosed recently with Dupreyten's Contracture and we have been told she needs a test to see if she also has remetoid artharitis as her fingers are bending over and she can't lay her hand flat. I am beyond scared that these shots had something to do with this and I let them give them to her. No doctors will ever tell me the truth as I have asked! Need I say anymore. She has no pain---yet however.
Elena
on
Elena
Gigi
on
We are Asian parents & my 6 year old daughter also diagnosed with pre puberty still need to confirm with additional blood work & X-rays .
Need help to understand what is luprone? Endocrinologist we went also told us if result come positive my daughter also need to take injection every 3 moth to stop early puberty? Is that same injunction you guys r talking ? Lupron injections are used to stop early puberty ?
Heather
on
This company needs to be sued!! My daughter has and is going through hell and as a mother there is not a damn thing I can do about it!! Her father and I feel horrible that we put her through this misery. For anybody who is reading these, DO NOT TAKE THE DRUG!!!!!! We need to stop them from hurting anyone else!!!!
Elly
on
When I was driving my car, my hands and neck stock and could not turn my neck right or left and could not take my hands toff the steering wheel. I was told by the Doctor to drink lots of milk. Indeed I was drinking lots of milk to avoid osteoporosis. That was a big lie. The very moment I was injected with Lupron, osteoporosis spread all over my bones. Triglycerites increased, and had heart time breathing. My lungs were very stiff and could not breath well. My belly blow up like I was 9 months pregnant. Everybody was thinking I was pregnant. Though I did not have a husband. had hart time breathing.
BP increased, braking of the skin of my legs, I thought I will die with this chest pressure and my bones shatering.
I could hear my neck bones cracking and it does that to this very day every time I turn my neck. I got very short now and my face shrinking due to the osteoporosis.
I have HTN. Many Doctors I have visited have no clue about Lupron Depot, and did not took me serious about my problems. In Michigan we cannot sue a Pharmaceutical company. Thanks to the republicans. Now I am fat with heart problems and no one can help me to sue those bastards who destroy my life. From the time I was injected with Lupron, by body Never recover for the better. I feel I am doomed. MICHIGAN REPUBLICANS GO THE HELL!
Mona Hawks
on
Nickolle Doyle
on
Laura
on
Unfortunately, my insurance company didn't agree and denied my pre-authorization for surgery. I requested appeal and peer review of my claim and was again denied, citing "not enough conservative treatment had been attempted". The insurance company said that I have to do Lupron for 6 months before I can re-submit for surgery. Basically, I am being bullied and coerced into this treatment by doctors that know nothing about me or my issues/family hx. My doctor is NOT happy with the insurance company and the decision. I have been reading all I can find on Lupron since being told this and can tell you that I plan on telling my dr to tell the ins company to shove their best treatment plan where the sun doesn't shine!! I will not be taking this poison and will continue to suffer and try to find alternate treatment to take in order to document enough "conservative treatment". Hope that nothing goes wrong during the waiting game!
Lou Ann
on
I have been getting epidural cortisteroid injections in my lower back and neck, multiple medications to treat the fibromyalgia, and other meds for my abdominal chronic pain.
Tabatha Evans
on
loss when I comb my hair thank you for your statement
bc
on
Kristin
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My 7 year old daughter just had the 3 month Lupron shot last week. The endocrinologist assured me that there are no side effects and no long term side effects. She eventually convinced me to put my precious little girl on this drug because her bone age showed that of an 11 year old rather than her actual age of 7. I could not find any information on Lupron with children other than what Abbott puts out for people to see. I thought I was helping her by putting her on this drug but now I am not so sure after reading all of your input. She has mentioned hearing things and feeling disoriented ever since she got the shot. She is also hot much of the time. I wish someone could explain this to me/us without there being any other motives (i.e. kickbacks from pharma companies). The endo said she receives nothing for prescribing Lupron and said that none of her other patients have had any problems on the drug. I hope I didn't just ruin my daughter's life by believing this drug could help her...
Carrie
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Emma
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Marnie
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Avery
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Sarah
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Selena
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Donna Norton
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Wendy
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Trena
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Nicola Walker
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Sarah
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Maryse Dezulmat
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shannon
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THANK YOU EVERYONE for your candid posts. I am sorry for all the pain and suffering that this drug has caused in all of you.
Until i read these posts I had no idea this drug was so dangerous. I took a course of lupron when my daughter was conceived through IVF. I have some of these same symptoms, but not severe. I was searching on line for long term effects of lupron use because I know it is a treatment in some cases for early puberty when I came across your posts. Shortness never killed anyone or gave them a life of constant pain. My daughter will NOT be taking this crap!!
Thank GOD for the internet!!!
Susan Staley
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David Redwine, M.D.
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David Redwine, M.D.
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Joe Simone
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Is she doing any add back therapy?
I would go to a licensed counselor and get out your feelings. Its tough seeing a loved one suffer but with the state my wife is in now I cannot risk getting in trouble with the law if she goes off the handle.
Michael
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My wife is on her second cycle of Lupron for endometriosis and life is horrendous. I have never seen her this angry and hateful towards me. I am trying to stay strong and positive. Can you give me any guidance? is it lupron?
Thank you
Michael
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My wife is on her second cycle of Lupron for endometriosis and life is horrendous. I have never seen her this angry and hateful towards me. I am trying to stay strong and positive. Can you give me any guidance? is it lupron?
Thank you
Helen
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karla
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Sara
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Julie Lessa
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I went back to my oncologist last week. She told me I was going to stop taking the Lupron. Said studies didn't show it actually worked for shrinking the tumor like they once thought it did.
Now I read everything you guys have gone thru. Every single doctor's appt I've had over the last year due to back pain, hip pain, "neuropathy" sounds like it was all due to this drug I thought was saving my life. I sure hope I don't have anything happen in the future due to this stupid shot.
Do not get the Lupron shot.
I'm due to get it again on the 2nd of August. I'm obviously not. Was there any side effects you all experienced from going OFF the drug? Not looking forward to those!!
Vicki
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Maddie
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While on this shot I took care of a 4 1/2 year old son, my ailing mother, worked full-time, handled the house, and finished my bachelors....I thought I was exhausted from all of these things, but after reading all of these things my horror has been realized!!!! And, by the sound of it, there is nothing that I can do.......
I am just going back to college this September to obtain my MPH (masters in public health) and it sickens me to think that I could start feeling worse....What can we do? Maddieg67@Yahoo.Com. Feel free to e-mail with suggestions.
Maddie
Diane Champion
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connie
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TeresaR
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Lupron put me in a "drug induced case of menopause". For 6 months I went thru the treatments. It was never, EVER touted as a permanent cure to endometriosis. While doctors may be telling you "I didn't know that", it's their own fault, not the maker's. This drug has been around more than 20 years, and I know for a fact I was told the following:
1. It's temporary.
2. Take it no more than for 6 months.
3. This is the only time you should take it, though it can be taken 2X in your life (2 6 month treatments).
4. It will put you in temporary peri-menopause, including hotflashes, etc, that actually comes with that condition. It means irritability. It means hot flashes. It means everything else that comes with that.
As for a study of 100 people, don't know who did that or when, but this drug has treated probably millions of people by now, in it's 20 years + on the market. If doctors are not using it for it's true purpose, that is the doctor's fault not the drug company!
Colleen
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Elisha Wheeler
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Jenny
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Diet is major. Johanna Budwigs diet guide is very helpful and I have controlled the bleeding by following the program. Last week I slacked off after months and consumed sugar and the bleeding started more heavily again. To me, fibroids are a warning that stress, diet or something else has thrown our bodies off balance. This is why removing body parts does not reduce our chances of getting cancer. Most other sites repeat pretty much but not as fully the advice given in Budwig's anti-cancer diet. But her program explains exactly why we are going through everything.
Donna Brandenburg
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Debbie
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Regina
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My first shot, I started to have blurred visions, heart palpatations, lower back pain, burning of my joints in the knee area. I called my doctor and explained to her the problems I was having.
She replied by saying that the drug Lupron would not caused these symptoms, I said to her that I didnt have any of these symptoms until I had this shot. I think every individual know his or her body. Nevertheless she is the doctor, so I just over look these symptoms and took the second shot after 3 months.
Now at this point, I have all the same symptoms from the first shot to now having memory loss. At the time I was 41, my daughter who was 19 said that I act like a old women. She didnt understand the seriousness of the drug. My daughther thought the situation was funny until I told her I believe that Lupron was causing me all these problems.
I told numerous doctors my theory about this drug, only to be brushed off and said that its all in my mind, I even called a couple of attornies who said that if I dont have any proof of my claims there is no lawsuit. Now 7 years later I happen to be watching the Erin Brockovich movie which aired Sunday April 7, 2013 for the first time and decided to look her up and read her story.
Once on her site she stated that she was taking emails about the drug Lupron. There seem to be complaints about the side effects of this drug. How ironic was that. This drug causes serious harm to people, and in this article you have Dr. John L. Gueriguian who was a medical officer for the FDA in 2008 saying not to use the drug LUPRON.
That should be a RED FLAG. Its time for the Manufactuer Abbott Labs to pay for all the harm that has been done to people who have taken this drug. I believe in KARMA, I also believe this company knew of the long term side effects of this drug.
I hope every person who was affected by this drug take a stand and not let them get away with this because too many lives have been destroyed and people have died. Since I've had those injections my life has not been the same. People who have had those injections have all the same symptoms, its not a coincidence. The main symptom seem to be Degenerative Bone Disease, and that is very painful.
Best Regards,
Regina
Tammy
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A simple procedure has turned into repeat surgeries.. 2011 i had laproscopic surgery for endometrial ablation done.. Exactly a year later i had a laproscopic surgery to remove large Cyst removed from my left ovary, and they were unable to remove my tubes due to scar tissue.. 72 hrs later The HELL l call life, is how i now know it..
Gut wrenching pelvic pain, through the front and completely out through my lower back.. l had every test, Diverticulitis, Crohn's ,blood work, blood work, blood work, all organ's checked, 2 colonoscopy's done, MRI's done, CT scans done, Ambulance Rides, several trips to the ER, resulting in being treated like l was a Drug Junkie..! All Dr's said " Ruling out possibilities" And still no answer as to WHAT THE SEVERE CHRONIC PELVIC PAIN is..
Now being an educated woman, l know that internet can and can't be a source of information. Well let me tell ya something.. l have read more articles from women, who suffer the exact same hurdles i have been through. Some articles are like a text book print out of everything i have been through. And now having been to the BEST woman's hospital in Ontario, Canada..
It was brought to my attention that the endometriosis, wasn't resolved after the hysterectomy surgery. And women with severe chronic endometrisosis still suffered. Some mentioned that they did get some relief for a few months after the surgery. Only to have the excruciating pelvic pain return. And the OB/GYN had no answer or cause the female anatomy had been removed.
But scar tissue still remained.
Lupron is now the medication they want me to try. Reason to enure that the pain is uterus/ovary related and not scar tissue. Understandable thrust into menopause with give them that answer, stop female cycle and see if the pain stops. lf pain continues evidently the anatomy isn't the problem.
NOW i do my digging and my research, and am POSITIVELY TERRIFIED to try this medication. Cancer is in my genetics (paternal grandma) and Heart Disease even closer ( mom and dad ).. And my mother developed it after taking HRT... And then 1 yr later had blood clots and heart attacks and heart bypass surgery..
I am beyond depressed, stressed and sickened with worry over this.. My employer is understanding to a degree, as all my absences are validated though medical support.. But for how long, will they accept that, And the thoughts of Lupron being the only medication available to help.. SICKENS me even more. l do have friends who have taken it and said its the best thing they ever did.. and some who said it wasn't.. l'm only 41 yrs old, and have a 9 yr old at home. Just the 2 of us, is it worth the risk, As she's already seen me go through so much...
Jessica Alcantara
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Rocshelle Jackson
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Lizzy
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I have went to hell and back and finally my life has felt somewhat normal now and then. I have lost all touch with my husband sexually, I have become someone I do not recognize sometimes when it comes to my mental health, I have contemplated suicide and become severely depressed and moody at times. There are also some good times and I have had lots of jobs but I have not been able to hod down a full time employment because I have bone pain and body aches, I still have not full control of my bladder. I turned forty six a couple of months ago and I sometimes feel like I am eighty and can not get out of bed, but my body aches so much laying there as well. My right leg feels like it's heavy and falling off all of the time and I have been told I have degenerative bone disease and that it is normal to have this. I am on thyroid hormone replacement therapy for life, and sometimes I can not afford the health insurance which I need for obvious reasons but mostly because I need blood test for the thyroid every year. I want to contact a lawyer, I wonder if anyone has done that and if there is a class action lawsuit for Lupron Depo victims. I just found out that my GYN has retired and only sees fertility patients once a month so I can not see her any more. I want to scream, and I cry but none of it helps. If someone could please comment I will come and read often as I can. My fear now is that the Lupron may have caused some type of cancer. I have pain and bleeding and my periods have become abnormal. I called to see an obgyn and they said it's probably just pre-menopause, but I suspect otherwise and would like to have some tests done but not sure what tests. I am currently researching online to see if there is a way to check for cancer linked to Lupron injections. Any thoughs or comments are welcome.
thanks in advance. Lizzy
Jerry Kessler
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Pam
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I am so sorry for those who trusted our system and had this drug. I pray you find some relief.
latasha
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Erin
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I wish I was better informed of the long term effects of this medication. Investigations need to occur as to why these side effects are not being explained to patients. Someone needs to once and for all take a serious look into this drug and file a national class action lawsuit on behalf of all of us who have been victims of Lupron.
Dep
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brandi Hanson
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Heidi
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Jeanette
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Leahhs9
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lacreia white
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Maryse Jean-Louis
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The T: No T No Shade: Lupron For The Treatment of Endomet... http://thet-mjlouis.blogspot.com/2012/11/no-t-no-shade-lupron-for-treatment-of.html?spref=tw
Marta
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Lori Kotok-Anderson
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Went to a orthopedic surgeon in 2005 and was told it was bursitis--and was sent to physical therapy. That did nothing. Feeling pain everyday, yet not knowing what to do I lived with it. Then again in 2010 knowing that something is not right went back to the orthopedic surgeon and was went to have and MRI. Finding a 17cm subcondrial cyst is it is defined and was told there is nothing we can do about it. To cut this "BOOK" short, went for a third opinion now in 2012, fould a wonderfual Dr. that actually listens, and he tells me that I have one of the largest subcondrial cysts he has ever seen, as did the radiologist. He described to me that the subcondrial cyst is actually a hole in the hip bone and then fills with fluids. The lightbulb went off--Realizing that the lupron has been known to breakdown bone mass. I know that the Lupron has been the cause of all my pain over these last 15 years and yet, no one wants to talk about it! My gynocologist said that there would be no affect!!!! I had spoken to an attorney about Lupron and since my injections and the law suit that had been settled, I exceeded the statue of limitations and the only was he would take my case is if I had cancer that resulted from these injections!!!! Now who is the real criminal! SAD..................
Rebecca
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What I want to know is why all of these people including men are having such severe side effects and yet the FDA has not stepped up took this drug off the market. This is insane. I will never go back to that doctor again. I will never recieve another injection like that again. She should have done the hysterectomy and been done with it.
If the company has already said we lied and made up most of the research then why hasn't it been taken off the market?! It's all about the money to these people. Not the lives they are making completely miserable and more than likely for longer than we take this poison. And that is exactly what this is. POISON.
Lee
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Ed C..
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christina
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I just want to let everyone know that if you are getting lupron shots for endometriosis, it is pointless. Lupron is nothing but a bandaid & on top of that it will cause other medical conditions. This medication only puts endo at bay for a while. It is not a cure.
Regards,
And best of luck
Christina
Diamond
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I say give it a couple of years and you will be googling Lupron like the rest of its SURVIVORS!!! This was meant as a last option for prostrate cancer patients, so why is it being forced on healthy women and girls? Also, I wonder how these doctors that took a vow to protect us sleep at night?? Is $1200.00 per shot worth my life turning into a living nightmare? What if somebody injected you or your children with this evil juice?
God said, VENGENGE IS MINE; I WILL REPAY. I will wait on the Lord and not look to man for answers. I simply post just to save on more human from a life of irreversible suffering!
Where is the FDA???? Why hasn't this poison been banned before now.
Britany
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Thank you,
Brittany
Ashley
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Kristen
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Robin
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Gineen
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I have given birth to a healthy daughter from that round, but 5 years later from using it, I am 31 and having some problems a 31 year old shouldn't be having. Doctors have been chalking my symptoms up to stress, but when I was researching my symptoms, a few pages about long term side effects of Lupron came up.
My hair is falling out, I have sever insomnia, I have mood swings I never really had prior to Lupron, I do workout pretty hard but I injure myself a lot and my recovery time is long from each work-out. I recently starts getting headaches something I never had.
I am seeing my family practitioner this friday and my OB/GYN next friday. I wonder if this is something I should really be considering. I have been under extreme stress for years now and I figure my body should have a handle on it by now. But despite my changes, they won't go away,
I hope I can find answers.
Kme
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Bonnie
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CASEY
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t slayton
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that i never had before the shot ,loss of words making me think longer before answering,extream tiredness,loss of all sexual desire,shrinking of the testicules by half of there size to start with,rash's,blurrd vision,sometimes feel like im going to pass out that scares me to drive,i cant get a good nights sleep anymore for burning up at night with no fever my temperture is allwaya 98.6, I was told my psa was 315 now it is 1,it has made it where i can urinate without being in so mutch pain after being diagnosed with stage 3 prostate cancer,i am a 54 year old industrial mechanic that isnt a happy camper when you look at the side effects of lupron and told to keep trying to work 12 hours a day 6 to 7 days a week for the govermant while feeling this way!
Irv Mesher
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Nichole
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Susan
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Prior to surgery, my speech and thought process slowed (little strokes?), I had trouble finding words, I suffered severe bone pain, headaches and depression. Although these symptoms went away months after the surgery, less than one year after the injections, I developed chronic neck pain, and a shaking neck - at 48! I thus look like an old woman; have osteopenia and some neuropathy. Waiting for the other shoe to drop, so to speak. I wish I had had a hysterectomy and never taken Lupron!
Angie
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I cannot agree more with Dr. John L. Gueriguian conclusions regarding Lupron Depot injections. I myself am a victim of the side effects and when I further researched the clinical studies via Abbott, I found a case study of approximently 100 people is NOT sufficient. In addition, woman have a higher tendency to be ignored of side effects, as most doctors or sales representatives of this company push it off as being "hormonal" rather than actual symptoms of a medical condition.
The Corporate Office of these companies should be held to their ethicial standards to ensure when they produce and market a drug that all data is accurate and available to patient. The FDA should be conducting a re-audit of the validation and clinical research data and compliants that have been filed since the release of this medication.
Regards,
Angie