Glynn, who used the bisphosphonate Fosamax for seven years, alleges her femur spontaneously fractured when she bent over to pick up something in April 2009. Glynn, now 58, states in her lawsuit that her leg was repaired with surgery and the use of rods. She was 54 when her femur snapped.
Merck is currently facing some 3300 lawsuits alleging the osteoporosis drug caused femur fractures with more than 1000 other cases linking the bone drug to osteonecrosis of the jaw (ONJ).
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In 2010, data from a study highlighted a potential risk of femur fractures in people taking Fosamax and similar bone-strengthening drugs. Having reviewed the data, the FDA added warnings to the drugs' labels, and cautioned doctors about the long-term use of bisphosphonates. In 2011, an FDA advisory panel also looked at the drugs' risks, which includes leg-fracture data. The expert advisers favored warnings and perhaps restrictions on long-term bisphosphonate use.