(Isotretinoin, which is a synthetic retinoid and a form of vitamin A, goes by several names including Accutane in the US and Roaccutane [made by Hoffman-La Roche] in the UK. Generic forms of Isotretinoin, however, are still available in the US since Roche’s patents for Isotretinoin expired in 2002. And the generic acne drugs are cheaper.)
Several family members of suicide victims in the UK - at least three suicides in 2012 were blamed on Roaccutane - have recently protested at Roche headquarters (its corporate company is in Switzerland but the global healthcare company has more than two dozen manufacturing sites and many offices worldwide). In the US, however, Accutane has been linked to suicide ideation and psychopathology for a number of years.
One doctor in Ireland (name not given) is defending Roaccutane. In a letter to the editor of Kerryman (April 23, 2014), its author says, “If Roaccutane was banned it would be disastrous for the small group of people who have very severe acne where nothing else will work. The acne support group in the UK reckon far more people suffer from depression and suicidal thoughts as a result of their acne, not their treatments….For the majority of my patients, their biggest regret with ‘Roaccutane’ is that they did not take it earlier.”
At the same time, the writer acknowledges that Isotretinoin is a very powerful drug and Accutane birth defects are “well known.” And it goes on to advise that acne patients need to be screened for signs of depression before starting the drug. If only dermatologists and other prescribing doctors had the time and/or inclination to do so…
One Accutane victim wishes her doctor had time to explain Accutane side effects. “Doctors…should tell their patients about potential side effects; they should take the time to talk to their patients,” Valerie says. “If my doctor only took five minutes to read about Accutane side effects and give me the option, even though I was probably vain in my 20s, I wasn’t naive.”
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Interestingly, the doctor doesn’t mention Accutane Ulcerative Colitis and other bowel diseases linked to the drug. The letter goes on to say that all Roaccutane patients get dry lips, dry nose and dry skin, and more serious side effects are rare. Not so, according to the manufacturer, who has paid more than $53 million to settle Accutane lawsuits.