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Taxotere Permanent Hair Loss Lawsuit

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Santa Clara, CA: Taxotere (generic name docetaxel) is a chemotherapy drug used in the treatment of certain cancers, including breast cancer. One drug side effect includes permanent hair loss, called alopecia. Taxotere lawsuits have been filed against Sanofi-Aventis, the manufacturer, claiming the drug company failed to warn of Taxotere hair loss.

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Taxotere Usage and Side Effects

taxoterecasepage2The FDA first approved Taxotere in 1996 to treat metastatic and adjuvant breast cancer. Of approximately 2.8 million American women with a history of breast cancer, about 75 percent (more than 2 million women) were prescribed Taxotere to treat their symptoms. Breast cancer is the most common form of cancer in American women, with 183,000 new cases diagnosed each year, and nearly 45,000 subjects die.

The chemo drug can also be prescribed to treat prostate cancer, non-small cell lung cancer, advanced stomach cancer and head and neck cancer. Taxotere (other brand names are Docefrez, and Docetaxel Injection) works by interfering with the growth and spread of cancer cells in the body.

In April 2009 the FDA issued a warning letter for a reprint carrier citing a study in the Journal of Oncology, which compared the efficacy of Taxotere and Taxol (brand name for paclitaxel) in treating breast cancer. The agency warned Sanofi of the following:

    Promotional materials are misleading if they contain a drug comparison that represents or suggests that a drug is safer or more effective than another drug, when this has not been demonstrated by substantial evidence or substantial clinical experience. Furthermore, promotional materials are misleading if they contain representations that the drug is better or more effective than has been demonstrated by substantial evidence or substantial clinical experience.


In a 2010 press release, Sanofi-Aventis reported that Taxotere has been used worldwide to treat more than 1.5 million patients, 100,000 of whom were participants in clinical trials. Five years later, the FDA issued another warning that "Cases of permanent alopecia have been reported". Before the FDA's update in 2015, the Taxotere label stated that hair generally grows back” after completing treatment. But Sanofi's studies indicated that 3 percent of patients experienced persistent or permanent hair loss.

Taxotere Studies

2006: A study by Dr. Scot Sedlacek at the Rocky Mountain Cancer Centers in Colorado found that 6.3 percent of breast cancer patients grew back less than 50 percent of their hair after they were given Taxotere in combination with Adriamycin (docorubicin) and Cytoxan (cyclophosphamide). The study concluded: “Such an emotionally devastating long-term toxicity from this combination must be taken into account when deciding on adjuvant chemotherapy programs in women who likely will be cured of their breast cancer.”

2010: A study by the Journal of the American Academy of Dermatology warned about “an increasing number of reports of permanent chemotherapy-induced alopecia,” and blamed Taxotere for some of the cases.

2013: A study published by the National Cancer Research Institute found permanent hair loss as a side effect in 10-15 percent of patients who took Taxotere.

Taxotere Lawsuit Allegations

taxoterecasepage1.Taxotere chemotherapy patients claim that Sanofi-Aventis failed to warn about the risk of permanent baldness, and in doing so, patients were deprived of making an informed decision to choose other chemotherapy drugs, just as effective as Taxotere, without the risk of alopecia. Women in particular who are living with this avoidable condition feel like they are still having to fight cancer.

According to the UK's Mirror.co (Nov 2015), Sanofi said the following: "Hair loss can affect some patients taking anti-cancer medications such as Taxotere. All clinicians are required to discuss the benefits and risks of any treatments with their patients. If any cancer patient has any concerns about hair loss they should discuss it with their clinician." One breast cancer survivor, whose hair didn't grow back six months after receiving Taxotere, told The Mirror that she would "rather have lost my breast than lost my hair."

A Taxotere lawsuit was filed against Sanofi-Aventis in the U.S. District Court for the Northern District of Ohio. Hattie Carson, who was diagnosed with breast cancer in 2004 and underwent chemotherapy with Taxotere, claims that it caused her permanent baldness and the manufacturer failed to adequately warn female breast cancer patients and doctors about the risk of permanent baldness from Taxotere. Carson's lawsuit states that, “Although alopecia is a common side effect related to chemotherapy drugs, permanent alopecia is not. Defendants, through its publications and marketing material, misled Plaintiff, the public, and the medical community to believe that, as with other chemotherapy drugs that cause alopecia, patients’ hair would grow back.”

Carson further claims that Sanofi-Aventis warned doctors and patients in Europe in 2005 and in Canada in 2012 about the risks of permanent hair loss from Taxotere side effects, but failed to provide such warnings to the U.S. patients and doctors until January 2016. (The FDA issued a warningin December 2015). Sanofi-Aventis is a French multinational pharmaceutical company based in France.

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TAXOTERE HAIR LOSS LEGAL ARTICLES AND INTERVIEWS

Taxotere Hair Loss Lawsuits Moving Forward in MDL
Taxotere Hair Loss Lawsuits Moving Forward in MDL New Orleans, LA: The 800 lawsuits currently enshrouded in Taxotere hair loss multidistrict litigation are moving forward by way of updated orders and directives issued February 1 by the US District Court for the Eastern District of Louisiana. Plaintiffs assert that Taxotere, a chemotherapy drug, triggered Taxotere alopecia (hair loss) that has been characterized as permanent [READ MORE]

Taxotere Docetaxel Side Effects Not Limited to Permanent Hair Loss
Taxotere Docetaxel Side Effects Not Limited to Permanent Hair Loss Washington, DC: The Taxotere hair loss lawsuit file continues to move forward, with various Pretrial Orders issued in the early part of the New Year with proposed Plaintiff and Defendant fact sheets due to be filed Monday (January 23). Meanwhile, Taxotere patients continue to deal with the frustration, disappointment and emotional turmoil that are the result of what has been for some, permanent Docetaxel hair loss [READ MORE]

Number of Consolidated Taxotere Lawsuits Jumps
Number of Consolidated Taxotere Lawsuits Jumps New Orleans, LA: It's only been three months since the Judicial Panel on Multidistrict Litigation (JPML) consolidated the federal Taxotere lawsuits, but in that time the number of Taxotere claims added to the multidistrict litigation (MDL) has increased dramatically, a sign that women are unhappy about allegedly being put at an increased risk of side effects. Sanofi SA faces allegations it failed to adequately warn women that the hair loss they experienced as a result of the cancer treatment drug could be permanent [READ MORE]


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READER COMMENTS

1991 I had brain surgery,radiation and chemotherapy and still have no hair growth in the back of my head. Can not wear my hair down. ???? Help !
Thank you !

Posted by Sherri Pfeiffer on

I really thought i was alone in this suffering. I had stage 4 uterine cancer, l lost all of my hair, eye brows, lashes, i was recently diagnosed at johns hopkins hospital with a tear duct condition, they said was the result of my chemo drug taxatere. I had a procedure done earlier this summer, where they put tubes and stints in my lower lids to release the fluid behind my eyes, which causes me much pressure, and a lot of grief. I am unable to do certain things because of the water coming from my eyes, like driving, reading, sewing all of which i love to do, and now the combination of all of these conditions have caused me much anxiety, my life as i knew it is over, i am a very independant person,and now i 'm unable to do things i want and have to do. When my hair grew back, , it came in very thin with large bald spots. I still have horrible spasms in my back, legs, and feet. I have been and am still reminded daily of this cancer, every day for the last 9 years, this coming december. I am a single woman, and have lost attractiveness, not feeling very confident to pursue an intimate relationship.

Posted by Mary kennedy on

Had taxotere in 2012 for breast cancer, lost all my hair, grew back but much thinner with a receding hair line. I had severe joint and muscle pain during the treatment. This pain has continued for 4 years from mild to severe at times. My shoulders, arms, legs, ankles and feet were the worst. I was diagnosed with torn rotator cuffs about a year after my treatment. Then I developed plantar fasciitis in both feet. Was not offered an alternative to taxotere, understood this to be part of the protocol for my breast cancer.

Posted by Janice Vincent on

I did not have breast cancer but I had uterine cancer I was treated with the same chemical they used for breast cancer my hair grew back but left with big bald spots it's been over a year and still hasn't grown back I've had body aches muscle spasms vision is bad chemo brain it's very devastating how much I've aged 15 years knocked off my life

Posted by Dawn garcia on

I had chemotherapy.went bald...not all my hair returned..I now have joint pain, muscle aches,..fluid retention weight gain.I also suffer from chemo brain.My muscles hurt. Due to the body shock of cancer chemo radiation you body developed fibromyalgia which I suffer from also. Please help me.

Posted by Laura Balcita on

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