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Humira Side Effects

Humira (known generically as adalimumab) has been linked to serious Humira side effects, including an increased risk of a rare but usually fatal form of cancer. As a result of this increased risk, the US Food and Drug Administration (FDA) issued a warning about the risk of Humira cancer, especially in adolescents and young adults. Humira, which is made by Abbott Laboratories, is used to treat Crohn's disease and symptoms of various forms of arthritis.

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Humira Infection

Humira is in a class of drugs known as tumor necrosis factor (TNF) blocker. Other drugs in the TNF-blocker class include Enbrel and Remicade. Humira can decrease a patient's ability to fight off infections, leaving the patient at risk of developing serious infections including tuberculosis and infections caused by viruses, fungi or bacteria. Some patients have reportedly died from these infections, which can spread throughout the body.

Humira Cancer Risk

cancervaccinefd In addition to an increased risk of serious infections, the FDA issued a warning in April 2011, that some patients, mainly adolescents and young adults who were taking Humira for Crohn's disease, could be at an increased risk of a rare cancer called Hepatosplenic T-Cell Lymphoma (or HSTCL). HSTCL is a cancer of the white blood cells, is aggressive and is usually fatal, according to the FDA. This risk was increased when patients used the TNF-blocker drugs such as Humira with either azathioprine and/or mercaptopurine.

In August 2009, the FDA announced that an analysis of TNF-blocker medications showed an increased risk of lymphoma and other cancers associated with the use of those medications in children and adolescents. That discovery resulted in an update of the boxed warning for TNF-blocker medications.

Humira Lawsuits

yazmindocumentsgavel A woman who took Humira for rheumatoid arthritis during a clinical trial filed a lawsuit against Abbott Laboratories alleging her use of Humira resulted in lymphoma. The plaintiff alleges she began Humira in early 2005 and was told she was at an increased risk of tuberculosis. She reportedly stopped taking the drug when she was diagnosed with lymphoma.

Meanwhile, a lawsuit was filed against Abbott Laboratories in April 2011, alleging that use of Humira caused a woman to experience permanent nerve damage in her feet, after she took the drug to treat Crohn's disease. The lawsuit alleges that Abbott knew about the risk of peripheral neuropathy before it marketed the drug for the treatment of Crohn's disease.

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HUMIRA LEGAL ARTICLES AND INTERVIEWS

Humira Medication Not for Everyone
Humira Medication Not for Everyone
June 12, 2011
San Francisco, CA It was just a couple of months ago that Humira was the subject of a warning by the US Food and Drug Administration (FDA) with regard to the potential for Hepatosplenic T-Cell Lymphoma, a rare cancer involving white blood cells. However, it was 18 months prior to the release of the warning in April of this year that the FDA first revealed an analysis of tumor necrosis factor blockers, such as Humira, and adverse reactions that could ensue. These particular Humira side effects came to light in August of 2009 [READ MORE]

Humira Side Effects Lawsuit Filed
Humira Side Effects Lawsuit Filed
May 21, 2011
Helena, MT A lawsuit has been filed alleging Humira side effects caused permanent damage to a patient who took Humira medication for Crohn's disease. The Humira lawsuit claims Abbott Laboratories knew about the risks associated with its medication, but did not adequately warn patients about that risk. This lawsuit is separate from another lawsuit alleging patients faced Humira cancer risk from using the medication [READ MORE]


READER COMMENTS

Posted by
Marie Scotti
on
Side effects include dirreha nausea and tiredness. Did not help

Posted by
Selena Buchanan
on
I took remicade for3years,then i had a bad reaction to it my doctor then started me on humira for chrons disease i kept complaining about how tired i felt i could bearly function.then i developed a lump under my arm and was told it was nothing to worry about and for a year was given antibiotics which didn't help it got bigger and more lumps developed i was in so much pain finally i went to another dr.and had to have them surgically removed.a year later it came back and also on my buttock.had another surgery.i also had the shingles.my eyes also bothers me.every month i break out in different areas.i have battled chrons for 45years and if i had of known about these side affects from humira i wouldn't of never taken it i'm off of it now. The doctor said after 2years it had weaken my immune system.i was so sick.wish i had of kept taking prednisone.i never want to be a guinea pig again.now I'm afraid to go to the doctors because i don't know what other damages humira has caused.

Posted by
DH Lee
on
If you intend on taking Humira do yourself the hugest favor in the world and actually research this drug before you start it. Don't take the word of the doctor as they get sold on medications by the drug vendor. You can obtain squamous cell cancer on this (which is treatable in the early stages and is survivable-on the black box warning). What they don't tell you is cancer most likely will come back in a different form. Small cell cancer was diagnosed for me because the drug attacked my liver and with me having Rheumatoid Arthritis already, the immune system is already low and cancer will spread like wildfire. Ask for something else and get this poison off the market

Posted by
mark sparks
on
I haVE ALSO HAd to have a cancerous tumor removed from my right kidneyI have also spent over6days in the hosiptal on life support since beging the HumiraMy wife is no longer able to work sincence keeping me alive isw now her full time job

Posted by
Mark sparks
on
I have severve loss of feling in my left fot and right hand I have also spent 6 days on life support since taken Humira

Posted by
Flint MI
on
Ive been on Humira for about 1 /2. I has sevre night sweats, fatigue a few days b4 shot and after shot i have 1-2 good days and then bedbound for 1-2 days were i am complely fatigued. Ive also broke my left ankle, sprained left ankle, broke left pinky toe. Also experiencing lower rt ectreme pain around kidney with excessive urination (everytime Iget up n walk, smh. Now in the last week i am expiencing sevre pain in lower back rib pain w/ slight left side lower back rib pain. The night sweats are so bad i soak my pillow. Idk. I have called humira nuses 2 report. Oh forgot I got shingles on humira. My spine MRI shows worse spodylosis n disc degenteration,ra dr wont acknoledge the results bc she didnt order them. Only thing I love about Humira is my knees never hurt hardly ever. Oh have developed frozen rt shoulder. I also still has excessive pain in rt hip,not aknowledged by dr. Prayers go out to all life threatening conditions. Im 48 yo n battle ra since dx at age 7

Posted by
todd north carolina
on
I was on humira 2012 through 2014 I was tired out 5 or 6 days till my next injection cycle was on it for chrons it did well for controlling the disease .the drug tires you out after couple of weeks.. I stopped drug and developed numbness in my feet and up my calves about 2 weeks after final infusion still persists today in my feet . ill never take it again... but it did control the chrons very well . im left with damage from the drug ... its a risky long term deal

Posted by
Paul Booth
on
I took humira for chrones disease in April 2011 after i started taking it i had many infections in my gastrointestinal tract had to have surgery in Jan 2013 so i had to stop taking it oct 2012 surgery in Jan 2013 was in and out of hospital for infections then Jan 2014 was diagnosed with heart failure then in Nov was told my heart was rapidly failing normal heart infraction is 40-60 percent my heart was only pumping at only 7 percent my cardiologist told me in need surgery asap had been in hospital for holidays for last 3 urs put it off till july 2015 had an LVAD device put in LEFT VENTRICLE ASSIST DEVICE PUT IN I NOW HAVE PROBLEMS WITH MY HEART AND GASTROINTESTINAL TRACT

Posted by
neil goodwin
on
I have been taking humira since 2015, and my doctor never mentioned cancer as a possible side-effect. A few months ago i got prostrate cancer and had an operation to remove it. I moved to the UK where the NHS first told me that there was a link to cancer and that they won't supply me with humira.

I am amazed that discovery health in South Africa, my private health care provider, allowed me to take a drug with such dodgy side-effects, or even the slightest risk of such health effects, and lost hundreds of thousands of rand putting things right through an operation and tests etc.

Posted by
Patricia Semen
on
Been battling Ulcerative colitis for 30+ years and suffered through years of prednisone side affects so doctor said it's time to try biological meds. Not even 1 year on humira and I have break through profuse rectal bleeding, a cyst on my thyroid and something that was not even a birth mark turn into melanoma.
Now have to deal with the severity of the melanoma praying it's caught early enough. I m so worried.. have 10 year old twins who need me.

Posted by
Trish
on
I injected Humira for RA for about 18 months and developed a triple negative, aggressive, fast growing stage 3 tumour in my breast. Am not convinced that sufficient trials are being done for long enough on this drug. Of course, I was told that there is no evidence that Humira had any part in the cancer developing - strange tho, as it is a TNF blocker. I'm female, mid 50's and caucasian and not a typical candidate for this type of tumour apparently.

Posted by
Kevin Stearns
on
been on Humira for over 12 yrs, was on study drug. no problems

Posted by
Marg
on
I have rheumatoid arthritis and was told to take this, but after reading the fine print on the FDA site and Humira site, chose not to. I looked for natural alternatives. Wheat grass, kelp and change in diet has helped me tremendously! Do your research people. Humira shuts down your body's ability to fight infection and cause fast growing and deadly cancers. You can get better without these cancer causing drugs. I know of a man that recently has been hospitalized and is on life support, because of going septic from taking Humira. How many innocent people have to die? Save your life and live. Don't take Humira!

Posted by
Morris
on
I have been using Humira to treat my Ankylosing Spondylitis since May 2016. The results have been very positive. I am no longer experiencing morning stiffness. I am able to take part in some activities that I had difficulty with before (ie. golf). I am in my late 50's, and of course the drug cannot reverse the effects that developed over the years (ie. fusion of some discs).

Posted by
Kathy aleman
on
Since I have met people with ra and psoriasis and Crohn's including my granddaughter which is symptom free I wanted to look into Humira and into Embril, to see exactly how drug biologics worked. I came across this site and read what people were saying and I wondered if they had tried Shaklee supplements with about a 70 to 80% organic plant-based diet meaning being tested and possibly finding out what allergies they had to certain foods. My granddaughter was highly allergic to Dairy beef and lamb. She has been on a Shaklee food supplement regimen and mostly plant-based diet for the last 13 years with no reoccurrence. I am not a doctor but I would be willing to share what I know and possibly refer people 2 others with more knowledge than myself.

Posted by
Alana
on
I have anchylosing spondylitis that started to degenerate my SI joints in my hips. I have bad low back pain. Sometimes unable to walk. I even got iritis two months ago in my eyes. I am 31 and have seen multiple rhaumotologists. Everyone is pushing for himura as the only choice or a comparable anti-tnf. Has anyone had a good experience w these drugs?

Posted by
Lisa
on
My husband was started on Humira for psoriatic arthritis in Sept and took a total of 3 injections before he started to have neurological side effects. He bagan with severe dizziness, double vision and at times a total loss of vision. He was hospitalized for 7 days and had every test done to figure out what was wrong. He had 2 spinal taps and that is where it was determined to be brain inflammation and was diagnosed with Encephalitis and Aseptic meningitis due to drug induced with Humira being the probable cause. He was in rehab for another 3 weeks. He has Ataxia, loss of balance, loss of coordination, slurred speech, blurry vision, and us dependent for all care. I am his primary caregiver and our lives have been uprooted!!

Posted by
Lori in WA
on
I took Humira a total of the two first shots and two to follow. After the last one I had such a bad reaction. My upper arm ached and my hand would fall asleep so bad it would take over a hour to be able to use it and that is if I worked at trying everything to get it to wake up..(tingled and hurt like hell), had problems with my eye sight, equal liberm ( I would try to stand up and keep falling back into my chair), I had sinus problems and my lower back was killing me...but what really got me was my right foot felt like every blood vessel broke in the side of my foot, could not walk for over a week, both feet and ankles, lower legs were fire red with extreme swelling and my legs ache all the time, I quit taking it and will never take it again or anything like it. its been two weeks now and my hand is still falling asleep, and still having a lot of swelling in my feet and legs, and eye sight is still not back to normal or my equal liberm.

Posted by
Carolyn A
on
I have been injecting humira on and off, mostly off for 4 years. I have RA. Problem is I'm terrified of humira so have been using low dose prednisone as needed. I haven't used humira since June because it gave me lupus type rashes three times and constant herpes infections. I'm 58 years old but feel 90. Very hard disease. I've tried everything, diets, fasts, supplements, even sat in a radon cave for 10 days. Wish there was a cure......I considered injecting today because I'm in a flare and my hands are getting slowly deformed. Sick of suffering.

Posted by
Stella Taylor
on
My husband was given his first infusion of Humira in July 2014, for Rheumatoid arthritis. Exactly two weeks later, he collapsed. He was put on life support, with a tracheostomy. In neuroscience Intensive care for one month. A further four months hospitalisation and rehabilitation. I am now his carer. His balance is poor, he has a weak left side and our lives are 'disabled'. His neurologist could find no other cause and reported it as a possible adverse reaction to Humira. We were told that as there were no other cases like this, it could not be certain of the cause. The neurologist said that she was 90% convinced that Humira was the only likely factor that caused this devastating event, from all the thorough tests that she, and other specialities did. He was treated in a centre of excellence-the John Radcliffe Hospital in Oxford UK

Posted by
Mary L Roeder
on
I was using Humira for rheumatoid arthritis and just this past February i was diagnosed with cancer on my tongue. It was the worst tumors the doctors have ever seen. Does anyone else know if Head, Neck and Tongue cancer can be a result of taking the Humira. I only took it about a year. Then I had knee surgery and they stopped me from taking it saying it was no longer needed.

Posted by
Neha nisha
on
If Humira got such a bad side affects why are doctors prescribing it to the patients!!!

Posted by
LillysMom
on
is there any link between taking Humira and storke?

Posted by
Catherine Shender
on
My ex-husband died on 2/22/2016 from the side effects of taking Humira. Per his death certificate, he died of prescription drug induced respiratory failure, septic shock, and pulmonary Tuberculosis. He had been prescribed Humira in July of 2013 for rheumatoid arthritis in his hands by a licensed rheumatologist in Santa Cruz, California.

He died at Mayo Newhall Hospital in Santa Clarita, California.
He was on a respirator for weeks and was unable to fight the infection due to his weakened immune system brought on by taking Humira. He tested negative for TB before being prescribed this drug.

Humira reduces one's ability to fight infections especially pnuemonia and TB.

Posted by
Anthony G
on
Got on humira after my chrons came back after a few years of remission. Started in november of 2015 and in about April 2016, I started having a rash on my feet, then my hands. The skin started peeling off in layers and also patches of psoriasis all over my body. Believe it to be palmopustular psoriasis, and psoriasis as a direct result of the meds. Dermatologist took a biopsy of my foot today to try and see what the cause of this us, and what it is. Now they suggested remicade, which I ABSOLUTELY DO NOT WANT TO TAKE, due to the serious lymphoma and cancer, liver and organ failure side effects, besides brain swelling, death, etc. I just want relief from my UC and chrons. I do not know if the psoriasis or palmopustular psoriasis is permanant, or will go away after stopping the humira, and also, remicade has a possible psoriasis side effect as well. How I could get this ppp as a side effect from a drug that is also supposed to treat psoriasis. I could use any advice. I cannot even work because my feet are so sore I can hardly walk, much less stand for more than 5 or 10 minutes at a time. I am going to try for possible disability, I guess, as I am certainly unable to work my life long profession of finish carpentry and kitchen and bathroom remodeling specialist. Any advice would be helpful.

Posted by
Christine
on
I started on Humira for Ulcerated Colitis disease August 8, 2014. I am fatigue all the time. I am anemic HGB 10.9 Lymphocytes are at 57 segmented neutrophils 31 and absolute neutrophils 1.5 also I have gained over 35 pounds and managed to lose 7. My doctor insist this is not the result of the Humira and I need to stay on this medication because I am at risk for colon cancer. I have dealt with my Ulcerated Colitis since 1975 and this is the worst I am feeling. I am just looking for answers

Posted by
Anonymous
on
I took Humira once(the initial dose of 4 pens) in June 2014/July 2014 to put my Colitis in remission and ended up having a SEVERE allergic reaction. In the hospital I was diagnosed hypereosinophiliac syndrome(HES). This syndrome is deadly if genetically inherited A year later from I was put on prednisone to keep that under control.

Posted by
Linda
on
I started taking humira because Cortison didn't help anymore for my Colitis. 1 year After taking Humira just after giving birth I got diagnosed with tuberculosis and my newborn baby too. The docs persuaded me to take it during pregnancy Even I had doubts. As appartently it's safe during pregnancy. What a false information. Now I and my Baby have to suffer. Don't take Humira or the like If you're pregnant or better don't even take it at all. It's definately a life threatening medication which should be avoided.

Posted by
Laurie T.
on
Husband was on Humira for psoriasis. It worked great but then a Doctor changed him to Embral. That also worked well. After 7 years on these drugs he was diagnosed with RCC and had to have Kidney removed. Cancer was hopefully contained in the removed kidney. But only time will tell. After researching RCC and Humira, and with the info on his tumor that they believe started growing around 5 years ago, I truly believe Humira is the cause of his cancer. Wish someone would believe me.

Posted by
Dr. Dee
on
I started Humira in the spring of 2015. I was told it was my best option to control Crohns. I progressively weakened over several months. I believe I was misdiagnosed as I have no symptoms of Crohns now that I am off Humira. I have bouts of paralysis, severe skin lesions, eye infection, twitching, difficulty sleeping. The list is endless. The company's nurse (Abbott) encouraged me to continue Gimme a despite issues early on saying that it takes 3+ months for the body to adjust. My life has been completely altered & I suffer daily. My husband & kids lives are altered. I barely can work now & spend hours at doctor's or physical & occupational therapy. DO NOT TAKE THIS DRUG OR ALLOW IT TO BE PUSHED ON YOU! Abbott packages it up nicely & sells it using home nurses as salespeople. It is dangerous & I should not have trusted the company nurse concerning the side effects. I should have known better & now my life is turned upside down.

Posted by
Gina
on
Any good news??? I have been on humira for 1 and 1/2 years. It helps with psoriasis and pain somewhat but now I have severe pain in neck area around my lymph nodes,

Posted by
kevin fountain
on
yes i took the drug humira for several years for my chronic psoriasis ,since i took humira i lost my job due to infection and swellen in my face and skin infection at least once a month,this has put me through per hell .the side affects

Posted by
Dirk Roman
on
In 2005 I started humira 3 mouths later I had a lump in my arm pit yes non hogkin's lymphoma now 5 more.

Posted by
Josh
on
My wife was taking Humira for her Crohns Disease, she was part of the Canadian study to get it approved for use to help with fistulas. She has been diagnosed with Stage 4 Adenocarcinoma which is on the outside of her bowel believed to have started on a fistula, which has spread into her lymph system and possibly liver. The prognosis is bleak, she is 43 with two kids 6 and 14. Where was the warning, and where is help from Abbott Pharm to help battle this nightmare. Chemo caused septis, 25 treatments of radiation is planned with surgery to follow , if there is no spread further.

Posted by
Frank valerio
on
66 yr old male with chrons. Really upset on reading all the bad. Side effects. They have me starting humeria. Scarey

Posted by
Anthony Bowen
on
I Was on Humira for 10 years for rheumatoid arthritis on May 19 2015 I was omitted into a hospital for emergency surgery for a tumor turned out to be stage 4 colon cancer which now has spread up in my chest and neck area. I am 46 years old..

Posted by
Kristina
on
The Dr. even said it was the Humira that caused my stage 4 follicular non Hodgkin's lymphoma. One year of treatment I'm in remission but have to have two years of maintenance chemo and am disabled. I'm 47.

Posted by
Billie Jean Edge
on
I started taking Humaria inJune 2014. I came off it in May 2015. Since then I have been having extreme joint pain and swelling, throbbing this is in my fingers, knees,elbows, wrist lower back.. I never had these symptoms until I came off of Humaria. its hard to use my hands sometimes I hurt so bad that I can't sleep. Does anyone have any suggestions on what I can take or do?

Posted by
Kentucky
on
My mom was taking Humira and developed sepsis and pneumonia. My mother was unable to fight off the infection due to taking Humira and she died Sunday, April 12, 2015.

Posted by
Washington
on
Humira caused me to get lymphoma. I had surgery, radiation, multiple rounds of chemotherapy and ultimately a stem cell transplant on June 5 of 2013. I nearly died when I "coded" in the hospital during the transplant. I have damaged vertabrae, neuropathy in my feet, and don't quite have the right balance still.

Posted by
Florida
on
Daughter took Humira for Crohn's disease. Now she has numbness in her hands and other body parts; she's 15.

Posted by
Anonymous
on
After using Humira for about 4+ years, I came down with palmoplantar pustulosis psoriasis all over my body and it started spreading, all over my hands and feet, between legs, and on my back. It is hard to walk because my feet are always feeling strong pain. My skin is peeling off my hands, feet and legs. My feet are having spasm every day and night.

Posted by
Anonymous
on
I started taking humira for pustular psoriasis on my right hand and my left leg . After only 4 injections I was covered with enterococcus bacteria and a worsening case of psoriasis from my scalp to the entire rest of my body. I was put in the hospital due to infection . Now I'm trying to find an attorney who will represent me . I have been told by doctors that it's very odd that humira would cause my psoriasis to worsen . But in my case it did and my life has been completely altered

Posted by
Michigan
on
Heart problems, growth of lumps, constant fatigue. I also have other health problems that I have been diagnosed with after using humira but not sure if they are from the humira or not.

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