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Diabetes Medication Lawsuits

A number of diabetes drugs have been linked in studies and lawsuits to serious drug side effects, including acute pancreatitis and pancreatic cancer. Some class action diabetes lawsuits have resulted in settlements with the plaintiffs. Other lawsuits are just getting underway.

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Diabetes

Whereas type 1 diabetics need to inject insulin several times a day to stay alive, type 2 diabetics are treated with a variety of glucose-lowering drugs, and combinations thereof. Type 2 diabetes occurs when the pancreas doesn't produce enough insulin to maintain a normal blood glucose level, or the body is unable to use the insulin that is produced.

Diabetes, a lifelong condition, causes a person's blood sugar level to become too high. Four main risk factors for developing type 2 diabetes are genetics, age, weight and ethnicity. Almost 26 million Americans have diabetes, and up to 95 percent of these cases are type 2 diabetes.

There are several classes of diabetes drugs that work in different ways to lower blood sugar (glucose). Sulfonylureas have been used to treat diabetes since the 1950s while the first drug in a new class of medications called DPP-4 inhibitors was approved by the FDA in 2006. Sitagliptin was the first DPP-4 Inhibitors approved, followed by a combined product of sitagliptin and glucophage and saxagliptin in 2007.

A group of dugs known as incretin mimetics includes Byetta, Bydureon, Victoza, Januvia and other medications.

Diabetes Drug Classes

  • Sulfonylureas
  • Biguanides
  • Meglitinides
  • Thiazolidinediones
  • DPP-4 inhibitors (gliptins, or dipeptidyl peptidase-4)
  • SGLT2 Inhibitors (sodium-glucose cotransporter-2 )
  • Alpha-glucosidase inhibitors
  • Bile Acid Sequestrant
For more information visit the American Diabetes Association.

Types of Diabetes Drugs

Actos (exenatide) Associated risks: bladder cancer, heart failure.

Avandia (rosiglitazone maleate) Associated risks: heart attack, bone fractures, liver failure, death.

Byetta (exenatide) Associated risks: acute pancreatitis, thyroid and/or pancreatic cancer. Byetta attorneys are investigating lawsuits for users diagnosed with Impaired Kidney Function; Kidney Failure; Hemorrhagic Pancreatitis; Necrotizing Pancreatitis and certain other cancers.

Invokana (canagliflozin) Associated risks: cardiovascular injuries, kidney failure and ketoacidosis, a serious condition where the body produces high levels of blood acids called ketones that may require hospitalization. Launched in 2013, Invokana has become a blockbuster for Johnson & Johnson. A recent FDA Public Health Advisory found that the SGL2-inhibitor is associated with diabetic ketoacidosis in otherwise healthy patients. Adverse event reports and clinical trial data also show that Invokana is linked with cardiovascular injuries and kidney failure. Invokana works by causing blood sugar to leave the body through urine and is the most popular medication in a class of Type 2 diabetes drugs called SGLT2 inhibitors, according to drugwatch.com. The FDA urges patients with any early warning symptoms, including nausea, vomiting, difficulty breathing, confusion, abdominal pain and unusual fatigue or sleepiness, to seek medical attention immediately.

Januvia (sitagliptin) (Januvia (sitagliptin) and Janumet (sitagliptin/metformin) are the first in a new class of oral diabetes medications, called dipeptidyl peptidase-4 (DPP-4) inhibitors.) Associated risks: acute pancreatitis, hemorrhagic or necrotizing pancreatitis, pancreatic cancer. A recent heart safety study June 2015 ruled out any association with Januvia and cardiovascular problems. The study also looked at other Januvia side effects and found that Januvia pancreatitis has some risk.

Victoza (liraglutide) Associated risks: thyroid cancer, pancreatitis, serious allergic reactions and kidney failure.

Farxiga (Dapagliflozin) Associated risks: ketoacidosis, a serious condition where the body produces high levels of blood acids called ketones that may require hospitalization.

Jardiance (Empagliflozin) Associated risks: ketoacidosis.

Onglyza and Kombiglyze XR (saxagliptin) Associated risks: ketoacidosis. The FDA in April 2015 found that patients in a clinical trial who took Onglyza have a 27 percent increased risk of hospitalization for heart failure. The agency also reported that Onglyza increases the risk of death from all causes, not just heart problems.

Rezulin (troglitazone) Associated Risks: liver and cardiovascular issues. Rezulin labels warn of increased risk of rare but serious liver problems.

Other diabetes medications are Alogliptin (Nesina, Kazano, Oseni) and Linagliptin (Tradjenta, Jentadueto).

Diabetes Drugs: Lawsuits Filed

Merck is facing more than 40 personal injury lawsuits alleging Januvia caused pancreatic cancer.

The Cherokee Nation in May 2015 filed a lawsuit against Takeda Pharmaceuticals, accuses the company of "misbranding"Actos sold to the Cherokee Nation for uses as being not approved as safe and effective. Actos (generic pioglitazone) was sold in the treatment of Type 2 diabetes to help lower blood sugar levels.

Other lawsuits have been filed against the company indicating Actos could potentially cause bladder cancer. Patients are also warned the drug could cause congestive heart failure.

Farxiga, Jardiance and Invokana lawsuits are being filed nationwide on behalf of patients who say they weren't warned about adverse side effects like ketoacidosis, heart attack, stroke, and kidney failure. The FDA issued a safety communication on May 15, 2015 for diabetes patients using Farxiga, Jardiance and Invokana . The entire SGLT2 inhibitor class of drugs may carry a risk of ketoacidosis. Lawyers say this risk is nowhere to be found on any of the SGLT2 inhibitor drug labels, which means that lawsuits could be filed against negligent manufacturers regarding failure to warn, among other allegations.

Actos Settlements

Takeda, the maker of Actos, agreed in April 2015 to a $2.4B settlement in thousands of diabetes Actos lawsuits alleging bladder cancer risk. On April 29, 2015 the New York Times said that Takeda "will put the money into a settlement fund if 95 percent of plaintiffs agree to the accord, according to which each claimant would get an average $267,000. However, the exact amount for each plaintiff will be evaluated based on cumulative dosage, extent of injuries and past history of smoking". Takeda faces about 9,000 product liability lawsuits in the US.

In a separate lawsuit, a Louisiana federal court in 2014 ordered Takeda and Eli Lilly to pay a combined $9 billion in punitive damages to a New York state man who claimed that Actos had caused him to develop bladder cancer.

Diabetes Drugs Legal Help

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DIABETES DRUGS LAWSUITS

Invokana Linked with Cardiovascular Injuries and Kidney Failure lawsuit alleging Invokana side effects including an increased risk of kidney problems and cardiovascular problems

FDA Warns of Ketoacidosis Linked to SGLT2 inhibitors Canagliflozin, Dapagliflozin, and Empagliflozin

Saxagliptin marketed as Onglyza and Kombiglyze XR possible increased risk of heart failure

Victoza Side Effects - Pancreatic and Thyroid Cancer

Januvia allegedly can cause cancer, pancreatitis and other side effects.

Byetta allegedly linked to renal kidney failure and acute pancreatitis.

Actos alleging bladder cancer, heart or kidney damage may have been caused by use of Actos...

DIABETES DRUGS LEGAL ARTICLES AND INTERVIEWS

Invokana Lawsuits Keep Trickling In
Invokana Lawsuits Keep Trickling In Trenton, NJ: We’re coming up to the first anniversary of a health and safety review conducted by Health Canada in May, 2016 with regard to Sodium-glucose cotransporter-2 (SGLT2) inhibitors: Invokana (canagliflozin), Forxiga (dapagliflozin), and Jardiance (empagliflozin). The move followed a similar review and a warning by the US Food and Drug Administration (FDA) with regard to the potential for cardiovascular injuries and kidney failure [READ MORE]

New Lawsuit Claims Drug Manufacturers Failed to Warn of Risks of Diabetes Medication
New Lawsuit Claims Drug Manufacturers Failed to Warn of Risks of Diabetes Medication Dallas, TX:A federal lawsuit filed recently over a popular diabetes medication claims that drug manufacturers failed to warn consumers of heart attack risks associated with the drug [READ MORE]

Invokana Lawsuits Will Remain in Federal Court In Philadelphia
Invokana Lawsuits Will Remain in Federal Court In Philadelphia Philadelphia, PA: A series of complex legal arguments and maneuvering with regard to jurisdictional issues may have served to briefly divert attention away from Invokana adverse events. However, plaintiffs are nonetheless steeled in their resolve to pursue compensation amidst allegations over Invokana linked with cardiovascular injuries and kidney failure [READ MORE]




READER COMMENTS

Posted by
Pauline Moilanen
on
I have been on met for min for over 15 years for my type 2 diabetes...recent visit to my doctor for routine check and drug refills I had my routine blood work done...Two days after my visit my doctors nurse called and said I was showing signs of kidney failure through my blood work...they referred me to a kidney specialist and they said to immediately discontinue metformin...I am curious to find out if there are any class action law suits out there...and what the results are...I now have to live with kidney disease for the rest of my life...

Posted by
Nina
on
My husband was on Metformin for 10 years being told he was PRE diabetic. Has had high blood pressure issues and it got so bad he ended up in the ER a few years ago. There after an MRI they found numerous cancerous tumors on both kidneys and suddenly took him off Metformin and told him he was not diabetic. Cancer has not come back it's been over 2 years but he went from stage 3 to stage 4 kidney disease to end stage kidney failure in a year's time so quickly. He almost died. They did emergency dialysis and now he is on dialysis until he can get on a transplant list. He is only 49 and this all started with high blood pressure. Any lawsuits for Metformin let us know as we believe that causes the renal cell carcinoma and now kidney failure.

Posted by
Gardner
on
I just started taking Metformin. I was diagnosed with type 2 diabetes. But all my readings are normal. So I don't beleive the diagnoses. But after starting the meformin my numbers have increased. I am scared that I shouldn't be on this drug. Please let me know if I should stop.

Posted by
Crystale Jones
on
I was on metformine and onglyza and now I have CHF

Posted by
Helen Slaughter
on
My husband was 53yrs old when he had his first stoke he was driving when it happen. Six months later he was rush to the hospital (UCI) because his potassium levels we're very high they were 10.5 when doctor said no one has that they know has never lived past 8 levels. They did emergency dialysis on him in order to flush the potassium levels down. He is or has taken every diabetic medication that is known to man, as follows, Lantus, 70/30 R, Kiwi pin injection , Metformin, Lisopril, Prozac, Asprin 350mg,ect..... Now he has kidney disease, seizures, ketoacidosis, mental depression, talk delusional, headache, lost balance
As his wife it's hurts for me to see him asking me what happen to him and why can't his words come out the way he thinking.
Legal help PLEASE.

Posted by
christine brennan
on
I'm on both metformin and Lisinopril how would I no if I qualify for a law suit I'm in and out of the hospital with pain and high blood sugar pls let me no what I need to do thank you

Posted by
Ste
on
First i'll say hi to everyone. I was on metformin witch made me go toilet alot. Discharging clotts of blood. Now i'm waiting for operation on my stamach as its prolapsed due to metformin. I'm now scared to go out of house cause of mental issues bout needing toilet. So if anyone knows if theres a case to sue let me know please

Posted by
BREE hickerson
on
I've been taking Metformin and glizerpride and Victoza! For a numerous amount of years! I was recently diagnosed with Kidney Problems! So now I will have to go thru all the stages because of a diabetic drug we believed would heal us but in the end it made my help much worse! Please let me know what these Billion dollar company's plan to do about it! Please send me info when it's available!

Posted by
Denise Daniel
on
My husband has been on Metformin for a few years now and was on it prior to developing CHF due to Type 2 diabetes. He also had kidney issues while on this drug although at the time we did not determine that. Just this week he was hospitalized due to this drug side effects. Lactic Acidosis, lactic acid levels were very high. They discontinued the drug now having to get more labs and follow ups with his MD and kidney doctor due to this happening.

Posted by
Marian Lee
on
My husband took Metformin for 5 years for his type 2 diabetes. He died of kidney failure in 2015. If there's a class action lawsuit, I want to be included.

Posted by
Naty V.Horejs
on
I been taking Metformen since 203.when l was Diagnosed o type 2 diabetes after l took the medicine.l don't what happened. I start having depression.and l was given a medicine. Avendia.and Metformen.the avendia.l end up having a Doble bypass.that been settled.and l still taking metformin.my depression is getting bad.l almost kill myself so many time.my husband still alive at that time.and wacth me 24 to 7 he work.3 days a week to be with me.l almost burnd our house down. Becouse lm in a lala land my husband hide all the knife.he is afraid that l might just stub my self.one day he told me that he come home our bedroom is luck and he open. And see me laying doun in the bed holding a big sharp knife. And my anxiety attack is getting bad l can't go to sleep. Im always in the bad mood. And l went to my doctor give me a anxiety attack medicine klonoPin.2 times a day and if l forget to take it l have anxiety attack. So l try not to forget l have to take it evryday for so many many years. and my anxiety attack still going on so does my Depression. I get scared easily. Just for a little thing.l have to beg my youngest daughter and her husband to live with me.and even if l take my klanopin. I still shake.im tired all the time.my daughter have to make sure that lm not going to hurt my self.lm her full time job.headache evryday. Light headed evry day.l still dont sleep at night. I sleep in day. and that's not good becouse l have grandchildren's that l want to visit.l have heart beat that.always going haywire.and chest pain.thst my heart doctor told me to increase. My blood presure medicine.l just want to know if someone can help me please lm 68.years old woman and a widow.of Navy veteran.and lm getting so tired hahing depression and anxiety attack evryday. Please let me know if some can help me thank you for your time. Naty Horejs.

Posted by
Randi Nara
on
I have been on metformin for years and I am now in stage 4 kidney failure. How can I find help. Patients must be warned of this complication.. Please help

Posted by
Shondrea Yvette Boyland
on
I was on metfo8 4 yes had my gallbladder removed and had pancreas problems I almost died can anyone help me if u know about a class action suit that's going on please

Posted by
Shondrea Yvette Boyland
on
I was on metfo8 4 yes had my gallbladder removed and had pancreas problems I almost died can anyone help me if u know about a class action suit that's going on please

Posted by
Dominique Moore
on
Since 2003 I have had to take lots of medicine to help control my sugar and I still have bad issues from them. I have taken Glucophage, Glucotrol, and insulin mostly.

Posted by
Karen Rice
on
I've been on glyburide for years, but it wasn't controlling my sugar, so I was placed on Glyburide with metformin and I'm feeling sick all the time, weak, bad taste in my mouth, just over all tiedness and I wasn't feeling that before. I also had to go to see a heart MD, because my pulse is always racing and it wasn't before and I know it's the Metformin. I'm now on bet-blockers PRN to control my increase heart rate. My MD took me off metformin for a while, but recently placed me back on them and that feeling is coming back. I need to find a better med to be on, or I prefer insulin. The metformin makes me feel as though I don't want to do anything. Takes away my strength during the day. I'm always tied. I believe this stuff is screwing up my heart, as well as my kidneys.

Posted by
tlee
on
Was on high dose of Metformin for fertility issues/PCOS. The Metformin put me in the hospital with kidney failure and acidosis. They immediately too me off the Metformin. That was in 2011. It is now 2017 and I am now stage 3 kidney failure and I still battle acidosis. Had a biopsy performed on my kidney and have kidney injury similar to a diabetic, however I have NEVER suffered from diabetes. I am only 44 years old and know that this medication damaged my body.

Posted by
Carlos Nievas
on
Metformin and Glyburide were the 2 meds prescribed to me for over 15 years. # years age I had kidney failure and now Im on Dyalisis.
I justv found out that in the States there is a law siut against Metformin. Im wondering if that was the cause of my kidney failure.

Posted by
Marcelino Lescano
on
I was taken glipizide and Metformin for several years for my diabetes type 2 and i notice two years age that i was having problem with anxiety and was prescribe escitalopram and take this medication for little more then 2 years. Anxiety cameback worst 3 months ago no doctors faund my real problem they said i was ok physicaly but i feel bad with dizziness 24/7. One day a decited to stop all my medication and anxiety stop not 100% but start to feel better, then may doctor ask me to start taken medication for diabetes slowly so i start with Glipizide and the same day Anxiety start again so he ask me to stop that medication and take metformin this medication do not lid me to anxiety but produce a pain to my kidneys. i never was sick for a real anxiety Glipizide give mi this problem what should i do can i start a class action agains company that make Glipizide because this medication leave on me just little discomfort whit the anxiety sometimes but i feel that i never should have been take a medicine for this problem

Posted by
charles williams
on
I was on metformin for several years ,in 2013 went to the er to fine out that I have stage 5 kidney disease and found out I have heart disease ,all from METFORMIN .I am on dialisis now 7 days a week 8 hours a day ,I do my treatment at home , I went to the doctor every three months now I go to the
doctor 3-4 times a week .I had to stop working last year I went from making a good living to just getting by .

What I need to know is there a lawsuit out.
Please help if you can .

Posted by
Robert Smith
on
I was on metformin since 2003 my doctor kept increasing my dosage and ended up putting me on Lantus also. In the end I was on 2000mg of metformin a day and 20 units of Lantus. I switched doctors last year after being hospitalized the end of July 2015. My new doctor did the normal blood work and the next day called and told me to stop the metformin immediately. When I went in for my blood work followup I found out I had moderate stage 3 kidney disease which he told me was caused from taking the metformin for so many years. If there is any type of lawsuit or anything you know might help me please email me. Thank you.

Posted by
gaynell thompson
on
I have always been on Glucophage, Glucotrol, and insulin
and now that I have started taking several other types of medicines do to various types of problems I want to make sure they are not related to these 3 medications.

Posted by
Bonnie Chick
on
My husband took Metformin for many years at 2000 mg a day. His blood sugar was always out of control. In February 2015 he was diagnosed with stage 4 renal failure and was in the hospital for 7 months out the 12. His last stay was two months, I took him in for chest pain and his kidneys failed while in the ICU. They did emergency surgery right in his room to install a temp catheter so they could start dialysis. His liver was failing, he has CHF, thyroid troubles, gout, high blood pressure, a pacemaker/defibrillator, which he is totally dependent on now and type 2 diabetes.. He goes to dialysis 3 days a week, at 4.5 hours each time. He has passed the one year date of his kidney failure. His urine output was nil, but he now produces urine, the kidneys do not filter it. Is there a lawsuit that is being filed for the metformin and the damages that have been done to him. He now takes 5mg of a diabetic drug called Tradjenta and units of Lantus injection, but only when he needs it. His blood sugar is under better control now with the Tradjenta and the Lantus. It is just now there are all of these other health issues that can end his life just as quick as the kidney failure can do. I know of two other people that are having health issues after taking Metformin. When I receive the information that I will get from you I will let them know also. Thank you so much for your help on this issue.

Posted by
Taronda Hayes
on
I hAve been taking byduron for three months and have experienced many side effects that I was not aware of. I now have a tumor that can turn to an invasive cancer

Posted by
Joan Agosto-Elwin
on
I used Actos, Victoza and metformin and have been hospitalized numerose times for kidney failure, been diabetic for over 15yrs and im affraid to end up in dialisis.I need a lawyer.

Posted by
John Mackrell
on
Developed a lactic acidosis and h pylori while on Metaforim . I was told I had diabetes and was on 2000mg of metaforim. Come to find out ii don't have diabetes

Posted by
James evans
on
I have taken actos and metformin and now have end stage renal failure.

Posted by
Laura I was on metformin for several months when i became ill
on
I hope you can help me.

Posted by
gabby
on
My mother has been taking metformin for like about three years now and her kidney hurts alot on her right side for some time.

Posted by
Sharon Kelley
on
My father had been on metformin for several years. In 2008, he became ill and was taken to the hospital. He was there for almost a month and succumbed to lactic acidosis, which the nephrology doctor had diagnosed as soon as he examined him and read his chart from prior admission. We would like to know if there is anything pertaining to a lawsuit for metformin lactic acidosis. It bothers me that these high-classed diabetes drugs qualify and metformin is questionable. Thanks!

Posted by
Alberto Rodriguez
on
I was on metformin for several years and while on metformin I had pancreatitis problem and was hospitalized for 2 weeks. I also suffered a heart attack thank god I came thru in great condition and I suffered kidney pain witch doctors said were kidney stones but no stones ever came out. Could all these problems have been caused by metformin because I was never told of these side affects.

Posted by
Tom Geisler
on
My mother in the in the ICU at the local hospital and is not expected to make it another 24 hours. She has been on Metformin for several years for her diabetes and her Kidneys began failing about a year ago. They are in complete failure today. She started dialysis in February but did not do well. She needs treatment for other health issues but because of her Kidney failure they can not treat the other conditions. I am a upset by her unnecessary early death but not sure what to do if anything.

Posted by
Teresa Ann Lewis
on
I have been taking metformin since 2000. My kidney hurts on my right side some time a lot.

Posted by
Shirlee Harris
on
My sister was taking drugs listed above and died of heart and renal failure from complications.

Send me any data to file a lawsuit on her behalf.

Thanks.

Posted by
robert Moore
on
My husband was on metformin for years last year he was diagnosed with stage 4 kidney failure and congestive heart disease..no testing or we would have known his renal function

Posted by
lue williams
on
I have been diagnosis with kidney failure after taking the listed medications. diabetic ketoacidosis in otherwise healthy patients. Adverse event reports and clinical trial data also show that Invokana is linked with cardiovascular injuries and kidney failure. Invokana works by causing blood sugar to leave the body through urine and is the most popular medication in a class of Type 2 diabetes drugs called SGLT2 inhibitors, according to drugwatch.com. The FDA urges patients with any early warning symptoms, including nausea, vomiting, difficulty breathing, confusion, abdominal pain and unusual fatigue or sleepiness, to seek medical attention immediately.

Januvia (sitagliptin) (Januvia (sitagliptin) and Janumet (sitagliptin/metformin) are the first in a new class of oral diabetes medications, called dipeptidyl peptidase-4 (DPP-4) inhibitors.) Associated risks: acute pancreatitis, hemorrhagic or necrotizing pancreatitis, pancreatic cancer. A recent heart safety study June 2015 ruled out any association with Januvia and cardiovascular problems. The study also looked at other Januvia side effects and found that Januvia pancreatitis has some risk.

Victoza (liraglutide) Associated risks: thyroid cancer, pancreatitis, serious allergic reactions and kidney failure.

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