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MRIs: A New Risk for People with CKD and Kidney Failure

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New York, NYAs if living with kidney failure and chronic kidney disease (CKD) weren't enough alone—it is now known that people suffering from kidney impairment face a dangerous problem if they undergo an MRI.

It turns out that they are at risk to develop a serious illness--Nephrogenic Systemic Fibrosis or NSF—from the gadolinium used as a contrast agent during the MRI. (The gadolinium causes the blood vessel patterns in the body to stand out for the scanner, allowing for the detection of tumors or abnormalities.)

mri kidney failureNSF starts by causing high blood pressure, muscle weakness and thickened, rough skin. As the illness develops, it causes pain, burning and itching in the affected areas. It can progress from stiffness in the joints to the point where the patient is unable to move, and it can lead to death. At this time, there is no known cure for NSF.

On May 7, 2007, the Food and Drug Administration ordered that a Black Box warning (the highest level of warning) be carried on packaging for each of the five gadolinium-based MRI contrast agents approved for use in the U.S. The warning advises that patients with kidney failure or kidney impairment should avoid exposure to these agents.

The question of whether the manufacturers of these products knew of the danger to patients with kidney disease is now up for determination in court. Lawyers for kidney disease sufferers who developed NSF after MRIs claim that in fact the manufacturers did know of the problem, and did not sound the alarm as quickly as they should have.

The FDA-mandated warning will affect a great number of people. CKD and kidney failure are on the rise in the American population.

The National Kidney Foundation says that 20 million Americans—1 in 9 U.S. adults—have CKD and another 20 million more are at increased risk for developing CKD. High risk groups include those with diabetes, hypertension and family history of kidney disease. African Americans, Hispanics, Pacific Islanders, Native Americans and seniors are also at an increased risk.

The Foundation also says that most people with kidney disease will not have any severe symptoms until the disease is advanced. People could undergo an MRI without knowing that they have kidney disease. Without knowing that the new warning applies to them, they could be unnecessarily exposed to gadolinium and the risk of NSF.

The Foundation says that early detection can help prevent the progression of kidney disease to kidney failure. It says that the following may be symptoms of the onset of CKD:

• Feeling tired and less energetic
• Trouble concentrating
• Poor appetite
• Trouble sleeping
• Muscle cramping at night
• Swollen feet and ankles
• Puffiness around the eyes, especially in the morning
• Dry, itchy skin
• Need to urinate more often, especially at night.

The risk to CKD sufferers from MRIs is just one more reason to be alert to the possibility of kidney damage. If you are in one of the high risk groups, and if you are having any of the symptoms described above, you should consult your doctor.


MRI Kidney Failure Legal Help

If you or a loved one has suffered health problems as a result of an MRI or MRA, please contact a lawyer involved in a possible [MRI Kidney Failure Lawsuit] who will review your case at no cost or obligation.


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