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Lisinopril Also Linked to Kidney Damage?

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Eau Claire, WIAlthough Joanne knows that Lisinopril has been linked to liver damage, she can't help but wonder if this ACE inhibitor, which is used to control high blood pressure, could also be associated with kidney problems.

Joanne, 64, has been taking Lisinopril since 2003, and it did keep her high blood pressure in check. But in 2009, she developed a nagging pain in her back. "I told my doctor about the discomfort, but he just chalked it up to arthritis," says Joanne. "But it got so bad that I went to ER where I had a CAT Scan and they found a tumor on my left kidney. What a shock that was.

"Within a week I had surgery: my left kidney was removed and some lymph nodes surrounding the area. The operation went well but I wound up with a nasty staph infection followed by pneumonia—it took a long time to recover, and I was in and out of hospital for about three weeks.

"I feel OK, but at the same time, I can't help thinking about my other kidney—it's a scary thought. I'm still on Lisinopril but my yearly physical is coming up so I'm going to ask my doctor to put me on a different med for my high blood pressure. Having said that, I don't know if Lisinopril played a role in my kidney problems but it is the only med I have ever taken (I know there are lots of meds out there that cause people a lot of problems, so I don't take any meds that I don't need), and up until this happened, my health was awesome. I've always been an active person and never sit around. And there's no history of kidney problems in my family.

"I didn't consider that Lisinopril could be to blame until my son found a lawsuit about Lisinopril online and he suggested I look into it. We read that a number of people were getting liver tumors from this drug, so why not a kidney tumor? Perhaps no one has linked Lisinopril to kidney damage but it just seems too coincidental, and having a kidney removed is rather drastic. You have to wonder whether these drugs cause more damage than benefits.

"I feel OK these days but I'm more worried about my other kidney and liver, and stress isn't helping any. And I have a 'phantom kidney'—I still have discomfort in my back— which my doctor said is normal. My son and I have been looking at alternative medicines—I'm glad my son is looking out for me—but I don't want to monkey with my health. I'm not a believer in a pill for everything but you don't want to mess with high blood pressure and wind up with a stroke. So I'm still living with Lisinopril, but hopefully just for a few more months.

"I think a little settlement would be nice for losing my kidney—it would make me feel a bit better, but how can it be proven? I guess an attorney could help me there."

According to Medicinenet.com, some of the renal causes of kidney failure are from medications.

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READER COMMENTS

Posted by

on
started taking and each test showed my kidneys getting worse. Was on renal failure 3 and after taking it each test got better. Doctor said it was from linsinpril. Bad drug.....do not take

Posted by

on
My mother was on this drug for high blood pressure. She had hoarseness went to the doctors. They took here blood pressure and it was 220. They did some other test and she is in kidney failure. The kidney doctor said it was because lisinopril. This is a bad drug.

Posted by

on
I have HBP and was put on Lisinopril yesterday. Took the first pill at 3pm and at 3am woke up with a dull ache in my lower back. It's my kidney! I took one more today but am now throwing them away. I've never had kidney issues and after researching the meds and finding several sites full of people who have had nothing but issues I'm done. I consider myself lucky that I didn't take it longer. Maybe this post will help someone else.

Posted by

on
I was taking Lisinapril for 2 years .. Came down with Lyphoma well started chemo.. But kidneys were shutting down have hadtrouble with kidneys before I became down with cancer.. DR. Found out I was taking Lisinapril for blood pressure she researched it and she took me off of it immediately .. They had to try a drug called the black box which no one had taken in the state to help well I knew their was lots of side affects but what else could I do so I took the drug in an IV and it worked.. Kidneys are better but had I kept taking that horrible drug.. Lisinapril I would be on dialysis or dead.. Couldn't finish my chemo if it hadn't worked .. I had the coughing along wth it..

Posted by

on
Make no mistake lisinopril is a dangerous drug! Four years of deviating arthrolgia (arthritis without swelling and another known side effect, leading to an amputation. They tell me I have no recourse because of the supreme court ruling of preemption.

Posted by

on
I was placed on lisinipril 10mg for Htn about 3 yrs ago. Last year my microurinalysis showed a slight increase in my levels. 6 months ago i stopped taking lisinipril. I now have stage 2 kidney disease,the lisinipril caused the increased protein in my urine.. i am presently taking Norvac.

Posted by

on
I had been on Lisinopril for many years. The coughing got really bad so I asked to be put on something different. After having lab work it had been discovered that my kidneys are stressed. I never related it to the lisinopril but know I'm wondering if that was the cause of it. Now I'm having to do lab work more often to have the kidneys checked.

Posted by

on
I have been on lisinopril for 5 years. I was diagnosed with a bleeding ulcer in the small intestine last year and have undergone many tests since part of my stomach has grown into the small intestine. I still have not had surgery and was put on nexium 40 mg 2x/day. In addition I suffer from fibromyalgia and was taking two 500 mg tylenol in the morning and two at night. I went for another test with contrast dye a month ago and was told they could not run the test because I was in stage 3b kidney failure. My surgeon ordered an MRI with contrast dye for the following week. At that time my blood test showed I was in stage 4 renal failure. I got in to see a nephrologist right away as I was panicking over this diagnosis. I have NEVER had kidney problems. He told me that the Nexium, Lisinopril and Tylenol all caused kidney problems. So JOHN who posted on DECEMBER 13, 2015 IS DEAD WRONG!!! My nephrologist took me off Lisinopril and I have taken myself off the 80 mg. of Nexium per day and now only take it every other day when i HAVE TO HAVE IT. I couldn't get in to see my GI doc until next week. I quit taking tylenol when I found out I was at stage 3B. Thank God I found a great nephrologist. I also bought an ebook online by a Naturopathic doctor and immediately quit the high protein diet I had been on. First, do no harm should be a tenet of the BIG PHARMA companies.

Posted by

on
It is unfortunate that so many people who have commented below were not properly informed by their doctor or pharmacist about their condition & the medications they were taking.

Lisinopril is used to treat high blood pressure (hypertension). That condition is very detrimental to your kidneys - it causes damage to the delicate mechanisms in the organ. Your kidneys are made of millions of processing units called nephrons, and when a nephron is damaged, it cannot be repaired. Overtime, as the damage accumulates, your kidney function eventually starts to decline.

Lisinopril helps to control your blood pressure by preventing an enzyme from making a hormone called angiotensin II, which would cause your blood vessels to constrict & raise your blood pressure even more. But the drug is only acting on this system to prevent the symptoms of a disease you already have - hypertension.

There is a correlation between the drug & kidney disease - hypertension can cause kidney damage & lisinopril is used to treat hypertension. But that doesn't mean there is a causation (direct link) between the drug & the kidney disease.

All drugs and substances come with risks - even if you take herbal supplements, you can have bad reactions or health consequences from them. Be informed about what you are taking, and understand the risks & benefits. Just because there is a risk (nothing is risk-free), doesn't mean that the benefits aren't greater. Make sure to talk with your doctor about your condition, and then talk with your pharmacist about the medications. Both are healthcare experts in their field, and can help you make informed decisions.

Posted by

on
Am a kidney transplant patient surgery done in 1995. In sep 2015 i was hospitalized for depression and i was treated for 2nd stage renal failure i was giving antidepressants that harm my transplanted kidney i need help am losing my kidney now

Posted by

on
A couple of years ago I was given lisinopil because the medication I was taking for high blood pressure was not working at all. I was surprised that my blood pressure had finally gone back to a normal level so I was very impressed by lisinopil as it turns out about eight months ago I started having shortness of breath followed by a very dry cough. At the time I didn't relate it to the medication until I finally after seeing many doctors one finally told me that the cough could be caused by lisinopil. I was completely shocked and did some intensive research online. The cough does come and go still but now I've been noticing that I'm having some kidney trouble I'm going to definitely go to the doctor to have my numbers checked but, I'm so upset to learn that the medicine not only has caused this nagging cough but it also might have effected my kidneys. Why is this medication still being prescripted knowing it could be hurting our kidneys. Thanks everyone for sharing!!

Posted by

on
I have been on Lisinopril now for over 15 years to control fluctuating blood pressure. I was diagnosed in 1987 with what was then called Fibrositis but now referred to as Fibromyalgia. An autoimmune disorder still vaguely understood especially by mainstream medicine which seems to have become wholesale dependent on pharmaceutical approaches. I have led a very active outdoor life, drink no alcohol and eat proactively towards healthy living.
My mother lost her left kidney to a tumor caused by what I now believe overdosing of Aldomet to control blood pressure. When my older brother reported a tumor on his left Adrenaline gland nestling on his left kidney, l began to interpret it all as a gene pool problem until. Recently, I was called in to have a second blood test due to an over supply of potassium in my blood which was challenging my kidneys to flush out the potassium. Now I am experiencing a collapse of ligament and muscle strength which is in turn creating gout and joint problems in my knees and ankles.
I am convinced beyond a shadow of a doubt that these symptoms have been evoked by medical misinformation and or miscalculation especially since reading Reduce Blood Pressure Naturally. I now can get far more efficient results regarding my blood pressure from an hour of meditation a day than the Lisinopril ever gave me. As for the deadly symptoms Lisinopril has created who knows what can be done! It is time to join voices about this outrageous misinformation or maybe more so the undisclosed negative information that has been concealed from the innocent public.

Posted by

on
This site is total and complete BULL SH*T! Lisinopril does not harm the kidneys at ALL! In fact, it has been shown to prevent kidney problems. The following was information taken from http://www.niddk.nih.gov/health-information/health-topics/kidney-disease/kidney-disease-of-diabetes/Pages/facts.aspx

Scientists have made great progress in developing methods that slow the onset and progression of kidney disease in people with diabetes. Drugs used to lower blood pressure can slow the progression of kidney disease significantly. Two types of drugs, angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), have proven effective in slowing the progression of kidney disease. Many people require two or more drugs to control their blood pressure. In addition to an ACE inhibitor or an ARB, a diuretic can also be useful. Beta blockers, calcium channel blockers, and other blood pressure drugs may also be needed.

An example of an effective ACE inhibitor is lisinopril (Prinivil, Zestril), which doctors commonly prescribe for treating kidney disease of diabetes. The benefits of lisinopril extend beyond its ability to lower blood pressure: it may directly protect the kidneys' glomeruli. ACE inhibitors have lowered proteinuria and slowed deterioration even in people with diabetes who did not have high blood pressure.

Posted by

on
I have been on lisinpril for around 6 yes the doc said I have kidney dieses stage 3 but reading some of the reviews it seems its doing more harm than good I want to stop taking them but will I have any withdrawal sytoms in doing so please help thankyou

Posted by

on
I am 49 years old and have taken lisinopril for high blood pressure for 10 plus years. About 5 years ago my doctor added the hctz portion. My blood pressure is perfect and has been for many years. Last night my doctor called at 7 pm (never a good thing to get after hours calls from a doctor). He told me I have stage 3 kidney disease. He also said my urinalyses from a year ago had shown signs of decreased kidney function and it had worsened since then. He wants me to continue to take the meds for another 3 months and get tested again. If my kidney functions have not improved he will change my bp meds. I'm calling him back today and telling him to change it now. Better to stop the damage from progressing now than live with the worse later. I am a married working mother of three and my husband recently had a stroke. I can't afford to get worse playing the lets wait and see game.

Posted by

on
I have just been released from the hospital for severe dehydration and problems with my kidney. I'm have taken visibility since 2007. The hospital took me off visibility and said it causes kidney problems. I am fearful for what May be next. Why on earth do we have meds that damage us and we do not know we are in danger. I'm very concerned as to what I'm facing. Pray everything will be ok.

Posted by

on
I have been on lisinopril for over 3 years. Now they want to do a CT Scan on my kidneys because they say it may have a tumor due to the lisinopril. They took me off lisinopril and put me on doxizosin as a substitute. CT scan in October. Pray for me.

Posted by

on
My husband was given Lisinopril for high blood pressure. His doctor per the instructions gave him 2 40 Mg pills to take each day at once, which means that he was taking 80 Mg at once. We didn't know what was happening to him, he just wasn't himself we took him to the doctor over and over. Finally he got so sick they admitted him, and they told us that he had Kidney Failure from the Liinopril, and the doctor took him off of the drug right away. He was put in intensive care, and he almost didn't make it. His body was poisned because his kidneys weren't working and clearing out the toxins out of his body. I want to know how many people are going be killed by this drug, or have to go through what my family has WITH THIS BAD DRUG....WHY ISN'T SOMEONE ONE SUEING THE HELL OUT OF THE DRUG MAKER OF THIS DRUG WHO MAKES TONS OF MONEY OFF OF IT. IT'S KILLING PEOPLE, my husband is now left to be taken care of our family and he is on Dialysis which is a hard thing for anything to go through!! I hope and pray that someone takes this drug off of the market, as it is listed as a BAD DRUG....AND IT IS KILLING PEOPLE, IT ALMOST KILLED MY PRINCE CHARMING!!

Posted by

on
I had high BP for years - until it reached 160/100. I was given Lisinopril, and my BP was great. But, all of the sudden, my kidney function tanked. Never had a problem, and now I was Stage III! After watching my function decline over several years, I am being taken off Lisinopril. I'm confused - why did it damage my kidneys?

Posted by

on
I was on Maxzide for hypertension for 3years and started having swelling problems, finally told I have Lupus (kidney type) in Oct, 2014. After my own research i found Maxzide was one of the drugs that can lead to Lupus. So my family doctor put me on Lisinopril 2.5 mg.
I told one dosage and was in the ICU within 24 hrs and put in an induced coma for 10 days with a tube in my nose to breathe. This was Dec. 4th 2014. Then a trachea was put in my throat. I was transferred to Drake rehab. for 8 days and needed a visiting nurse when released on 27th.
My memory is sketchy now and I stumble a lot, a big ugly scar on my neck in sight for the rest of my life and all this was avoidable. I have serious edema and so ugly when it happens I stay in the house, lips swell and face. I just cry. What happen to doctors doing research before they prescribe a drug for seriously ill patients?? My sight and hearing are also affected but the biggest worry is my kidneys, since I just found out that Lisinopril is not to be prescribed for anyone with autoimmune diseases. I hope something can be done about this drug, soon. maybe enough of us speak up, it will. I am talking to an attorney now. I have photos of me in the icu and at my worst. Always have pictures taken by a family member. I hope helps someone. Hugs.

Posted by

on
I had been on lisinopril for a few years when in 2012 my daughter came home and found me unconscious. She called 911 and I woke up in the ER and was told that my kidneys were failing. After a week in the ICU I was discharged. Two months later after routine bloodwork, my doctor called and told me to return to the hospital where I spent another week in ICU then was discharged and still given lisoprinil. Further blood work showed my kidneys were still failing and I was sent to a Kidney Specialist who immediately said that the lisinopril was ruining my kidneys!! What I would like to know is why my family doctor didn't realize that what he was prescribing me was killing me. On my first visit to the ER my body temp was 64 degrees. I was practically dead from this drug.!!

Posted by

on
I have been taking Lisinopril for almost 10 years. Last March I had a routine Physical and blood work came back with low kidney function! I was retested a month later and it was even lower! I was sent to a Nephrologist and began to fight to repair my kidneys. I did not have protein or sugar in my urine but it had a rotten egg odor and was cloudy and foamy. I continued Lisinopril and no matter what I did ( decaf coffee, no salt, low protein diet, etc) my kidney numbers were still sinking. My Lisinopril dosage was cut in half and my kidneys finally started getting better. I began to suspect Lisinopril was the drug responsible and I did my own testing at home. When I stop taking Lisinopril for even a few days, my urine is clear, odorless and not foamy. I have had severe pain in my feet that also improves when I stop taking Lisinopril.

Posted by

on
Have been on lisinopril for about 3 months for high bp..blood work before showed my kidneys were fine..but as of today my kidney numbers are bad.my dr wants to run another blood test and do a ultra sound and Doppler on my kidneys..but he wants me to continue taking the lisinopril....

Posted by

on
While reading the discussions concerning linisopril, it causes me to ask a question to those of you that use it. I have recently started using linisopril http://onlinepharmacyreviews.org/ingredients/lisinopril myself. I began taking it for one reason. I was taking a beta blocker and then found out that since I also use insulin, I was told by the FAA that it was an "unapproved" practice for me to take them together because a beta blocker masks the telltale signs of hypoglycemia, which could be bad if flying an airplane. So—-enter linisopril. Question is this. I noticed that the linisopril seems to lower my blood pressure quite nicely, but my heart rate seems much higher at rest than it was before. I read that it was something called reflex tachicardia, and was caused by the heart sensing the lower blood pressure and beating faster in an attempt to bring the pressure back up. Have you others also noticed a rise in resting heart rate? and did it level off after you'd been on linisopril for awhile?? Also, I will be watching the other numbers closely to ensure that I am not part of the .02 percent that was spoken of.

Posted by

on
Took Lisinopril for three years. Had severe knee pain, leg muscle cramps. Had to have injections in knees. Developed stage 3 CKD. Stopped taking lisinopril last year, knees started getting better in three days, muscle cramps stopped. Take atenolol now, works better, no side effects and costs much less.

Posted by

on
I have been on Lisinopril for years and I have had this chronic pain in my upper right side could Lisinopril be the cause? The doctors are puzzled by the pain and can't seem to find a reason for it . Thank You

Posted by

on
My Dr. switched my blood pressure meds about two weeks ago (one was lisinopril). Since then, I have been experiencing more pain in my body than usual. My family doctor wants me to cut the dosage in half do to kidney damage. Most of which I started to develop when I was put on Byetta. Another bad drug. Since I took that drug, I have had nothing but trouble.

Posted by

on
About two weeks ago before my mom was admitted into the hospital she was very dehydrated (she said she felt the urge to constantly drink water). A couple days after that she began to lose her appetite, everything she ate made her nauseous. She tried eating fruits and veggies it didn't work. The week before she was admitted to the hospital she went to the doctor because her prescription of Lisinipril and norvasc needed to refilled she also needed to go because she was concerned of the loss of appetite. The doctor did some blood work, Within a couple days they called to say you need to come back immediately. Before she went to the doctor she threw up she also had fatigue and swelling in the feet, face and hands with hives around her abdomen and arm. The next day which was a Saturday she went to the doctor and they informed her that both her kidneys have failed and are working below 10 percent. She was then admitted into the hospital the same day.My mom has been taking Lisinipril since 2007... She is now doing hemo-dialysis, which is VERY costly..she does not have insurance and the doctor said she could have died at any moment within two months if she did not seek some type of treatment. She is currently in the hospital but they wont keep her for long if she cannot pay for her treatment and surgeries. She has three kids, her youngest child (my brother) has autism 6,8,&17. If she passes away (god forbid) I would have to take care of my younger siblings which I wouldn't mind, but its alot of stress for 17yr old. I having been praying she gets better, I want people to be aware of these drugs and somehow help us get justice.

Posted by

on
I was severely dehydrated about 4 days ago. When I got to the ER they of course did blood work and hooked up an IV. When the labs came bk the Dr was amazed that my kidneys were completely shut down
After looking over my list of meds they stated that the lisinopril was the reason they shut down. They sent me to OSU East and those Drs said the same. After being released and seeing my own Dr, he said I may have about2% damage. That since I was pretty healthy I should make a ccomplete recovery. Maybe I was one of the lucky ones who got it in the nick of time but Im still mad. There should be some sort of justice for my pain and suffering. I have a husband and 2 kids that were scared to death that I might die.

Posted by

on
I was started on Lisinopril a little over 2 months ago for mild hypertension(very mild) and was told since I am a diabetic that it would help protect my Kidneys. I was scheduled to return in 2 months for bloodwork and when they got the results the Doctor's office called and urgently requested that i come back in for repeated tests. The twin sets of tests showed my kidney function had decreased 50% in 2 months.I was imediately told to stop taking the lisinopril and asked to drink lots of water and I am being scheduled for a Renal Ultrasound and renal doppler. I also just had a lung CT because of a dry cough that I was told was probably the lisinopril as well. I am confused as to what to do now.

Posted by

on
I was put on lisinopril,2 days of taking it I developed a inflamed liver, stomach swelling and now into my 3 rd day of chronic kidney inflamationnand pain and fatigue.this was because I had a little high blood pressure...what a nightmare!

Posted by

on
I had normal blood pressure forever,I am ^0 year old male with many health problems.Over 2 years ago My Dr said I have protein uria .He prescribed lisinopril because It has mutiple uses.One for blood pressure ,the other function of the drug is to protect your kidneys.That may sound crazy but you can research it.Hope this helps

Posted by

on
I was taking this ,my pc upped the dose and in 21 days I felt that my hip area was going to fall off. I stopped and feel better. as Scott says "Who allows these companies to use us as LAB RATS?"

Posted by

on
I now have kidney disease as a result of taking lisinopril. My kidneys are functioning at 40%, but when I was first diagnosed, they were only functioning at 19%. My kidney doctor told me the kidney failure was most likely due to my taking lisinopril. My liver enzymes are a mess as well. I'll probably die of either the kidney disease or the liver problems. Thanks lisinopril! Why isn't there a lawsuit for folks like us who have kidney disease as a result of the lisinopril?

Posted by

on
I was taking lisinopril since 2010 for high blood
Pressure. Last April 2012 I had protein in urine. Again this april 2013 my kidney function tests were abnormal. I questioned whether it was the medication and upon me questioning the doctor switched me to norvasc. He said in some people lisinopril can cause stress to the kidneys. I'm sure over a prolonged period of time stress causes other problems to develop. Be your own best doctor. Question everything!

Posted by

on
Took My fiance to Dr 2 weeks ago for depression, her blood pressure was 130/100 so they put her on lisinopril which i thought was odd, no issues with high bp in the past. Now we are dealing with low blood pressure 90/52 and now all of a sudden the kidney numbers are down she is currently in the hospital, there were never any blood Work done prior to check the kidneys before given this medication. 36 year old female....what can be done about this if anything, no kidney issues before taking this medication for almost 2 weeks. Thanks Alot,......Ryan

Posted by

on
I just completed an annual physical. This morning my Doctor's office called and said that they are taking me off of Lisinopril and switching me to Norvasc (Amlodipine). The reason given was that my test results indicate unexceptable kidney numbers. Whatever that means. Guess I'm making a trip to Walgreen's after work today.

Posted by

on
I am now taking atenolol 10 mg, does any body know, what problems could you experince when taken for long time.

my doctor told me that I am going to put you in lisnopril to protect your kidney and reading from on line this medication does a lot of harm bebefit. please a lert me as soon as possible.

Posted by

on
I've been on lisinopril a long, long time, probably since the late eighties.
I have experienced some low back pain on my right side in the morning but just thought it something benign and it would go away after urination.
Now I'm wondering after reading about this ladies tumor on her left kidney if there is a relationship with the pain and the lisinopril after all these years, I do not want to lose a kidney!

Posted by

on
My doctor took me off Lisinopril because he said it was damaging my kidneys as evidenced by increase protein in my urine.

Posted by

on
I took this medication for three years perscribed by my doctor. I now have stage 4 kidney failure and will probably end up with a transplant according to my doctor

Posted by

on
I have kidney infection from taking lisinopril.

Posted by

on
In 2003 I was prescribed Zyprexa and in 2004 I was told by my doctor to go in and get checked for diabetes. Sure enough, I had diabetes. I was then prescribed Seroquel and two months later I was told that was a bad drug by my doctor again. In 2009 I was prescribed Lisinopril and have been on it since. Who allows these companies to use us as their LAB RATS?

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