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Coumadin can be a very effective drug in preventing life-threatening events in patients who have Deep Venous Thrombosis (DVT) or Atrial Fibrillation (A-Fib). However, Coumadin (known generically as Warfarin) is also one of the most complex drugs to use safely because it can interact with a variety of foods and medications.
Physicians need to carefully examine the medical history of patients who are candidates for this drug, and also verify that the patient is not using one of the 100 other prescription medications that are known to have dangerous interactions with Coumadin.
In addition, a number of over-the-counter drugs and herbals also have dangerous interactions with Coumadin. Genetic markers are available to determine which patients are at greater risk for Coumadin adverse reactions and serious Coumadin injury.
Use of Coumadin during pregnancy or risk of pregnancy is very important to avoid, since Coumadin causes a very characteristic set of birth defects, marked by bone hypoplasias (resulting for instance in "pug nose") and brain damage resulting in mental retardation.
Coumadin Birth Defects
The medication guide for Coumadin warns that women who are pregnant, or planning on becoming pregnant, should not take Coumadin. Those who take Coumadin and could become pregnant are advised to use effective birth control because Coumadin can cause death or birth defects to an unborn baby.
Meanwhile, women who are breast-feeding are warned that Coumadin may increase bleeding in the baby.
Physicians need to warn their patients to report immediately if they experience any of a series of Coumadin side effect symptoms that typically precede more serious adverse reactions: Unusual bleeding or bruising; black or bloody stools; blood in the urine; tiredness; unexplained fever; chills; sore throat; stomach pain.
Coumadin Side Effects
Other serious Coumadin side effects include death of skin tissue (signified by pain, color or temperature change to any area of the body), "purple toes syndrome," allergic reactions, liver problems and low blood pressure.
The worst scenarios for Coumadin injuries involve hemorrhagic stroke or aneurysm—both involving blood vessels that burst in the brain and fail to be self-limiting due to the drug's blocking of normal clotting that otherwise would stop the bleeding.
File your Coumadin (Warfarin) ClaimIf you have had an adverse reaction to Coumadin (Warfarin) or a severe, life-threatening bleeding episode, please contact a lawyer who will evaluate your claim for free, by clicking on the link below.
Last updated on Dec-5-10
COUMADIN (WARFARIN) ARTICLES AND INTERVIEWS
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