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Coumadin (Warfarin) is an anticoagulant medication, used to prevent the formation and migration of blood clots (known as thrombosis and embolism). Although the medication is effective, Coumadin side effects can be serious, and involve interactions with a wide range of other medications and food. Furthermore, Coumadin birth defects, including brain damage, have been reported.
Coumadin can be a very effective drug in preventing life-threatening events in patients who have Deep Venous Thrombosis (DVT) or Atrial Fibrillation (A-Fib). However, Coumadin (known generically as Warfarin) is also one of the most complex drugs to use safely because it can interact with a variety of foods and medications.
Physicians need to carefully examine the medical history of patients who are candidates for this drug, and also verify that the patient is not using one of the 100 other prescription medications that are known to have dangerous interactions with Coumadin.
In addition, a number of over-the-counter drugs and herbals also have dangerous interactions with Coumadin. Genetic markers are available to determine which patients are at greater risk for Coumadin adverse reactions and serious Coumadin injury.
Use of Coumadin during pregnancy or risk of pregnancy is very important to avoid, since Coumadin causes a very characteristic set of birth defects, marked by bone hypoplasias (resulting for instance in "pug nose") and brain damage resulting in mental retardation.
Coumadin Birth Defects
The medication guide for Coumadin warns that women who are pregnant, or planning on becoming pregnant, should not take Coumadin. Those who take Coumadin and could become pregnant are advised to use effective birth control because Coumadin can cause death or birth defects to an unborn baby.
Meanwhile, women who are breast-feeding are warned that Coumadin may increase bleeding in the baby.
Physicians need to warn their patients to report immediately if they experience any of a series of Coumadin side effect symptoms that typically precede more serious adverse reactions: Unusual bleeding or bruising; black or bloody stools; blood in the urine; tiredness; unexplained fever; chills; sore throat; stomach pain.
Coumadin Side Effects
Other serious Coumadin side effects include death of skin tissue (signified by pain, color or temperature change to any area of the body), "purple toes syndrome," allergic reactions, liver problems and low blood pressure.
The worst scenarios for Coumadin injuries involve hemorrhagic stroke or aneurysm—both involving blood vessels that burst in the brain and fail to be self-limiting due to the drug's blocking of normal clotting that otherwise would stop the bleeding.
File your Coumadin (Warfarin) ClaimIf you have had an adverse reaction to Coumadin (Warfarin) or a severe, life-threatening bleeding episode, please contact a lawyer who will evaluate your claim for free, by clicking on the link below.
Last updated on Nov-5-10
COUMADIN (WARFARIN) LEGAL ARTICLES AND INTERVIEWS
Is Coumadin on the Way Out?
Seattle, WA: Because it has been around for so many years, Coumadin was widely regarded as the gold standard for anticoagulant medications. New medications have come along to replace Coumadin, claiming to not carry the same risk of Coumadin side effects - or the same need for blood monitoring. But because Coumadin (known also as warfarin) has an antidote, it has survived competition from the newer drugs [READ MORE]
Drug Tops Warfarin in Important Study
Chicago, IL: Johnson & Johnson and Bayer AG's blood-thinning drug Xarelto was better at preventing strokes in patients with erratic heartbeats without increasing the risk of bleeding than warfarin therapy, according to a new study [READ MORE]
Race to Replace Warfarin Chases a Potential $20 Billion US Market
Washington, DC: It's been around for 60 years and is one of the most common, go-to blood thinners prescribed to patients as a means to break up—or ward against—blood clots. But Warfarin, known commercially as Coumadin or Jantoven, is a complex drug that's not easy to get right. Until recently, methods used to determine a patient's suitability and tolerance for Warfarin have been described as "archaic. [READ MORE]
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