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Victoza Side Effects

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In March 2013 the US Food and Drug Administration (FDA) announced results of a study suggesting Victoza side effects could include an increased risk of Victoza pancreatitis. Victoza has already reportedly been linked in animal studies to an increased risk of a rare thyroid cancer, according to the FDA. So far, no Victoza lawsuits have been filed, although other drugs in the same medication class are the subject of lawsuits.

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Victoza Pancreatic Cancer

pancreas_januvia On March 14, 2013, the FDA issued a Drug Safety Communication, alerting the public to a study that suggested Victoza and other type 2 diabetes medications were linked to an increased risk of pancreatitis and pre-cancerous cellular changes, called pancreatic duct metaplasia. These risks were reportedly found in a group of drugs known as incretin mimetics, which includes Byetta, Bydureon, Victoza, Januvia and other medications.

At the time, the FDA said it was not changing the safety warnings of the drugs, but that it was reviewing data from the study, including requesting the methodology used so the agency could investigate the risk of pancreatic toxicity.

Other drugs in the incretin mimetic class have been linked to an increased risk of acute pancreatitis, including fatal and nonfatal instances of the condition. When Victoza was approved, the FDA noted that in five clinical trials of Victoza, there were seven cases of pancreatitis in patients using Victoza, compared with one case of pancreatitis in a patient who used a different diabetes medicine.



Victoza Thyroid Cancer

On April 19, 2012, the public advocacy group Public Citizen filed a petition with the FDA requesting the agency remove Victoza from the market. Public Citizen cited the risk of thyroid cancer, pancreatitis, serious allergic reactions and kidney failure as outweighing any possible benefits to the drug. In a news release, Public Citizen noted that two FDA pharmacologists and an FDA clinical safety reviewer advised against approving Victoza.

Victoza, known generically as liraglutide, is used to treat type 2 diabetes and is made by Novo Nordisk. It was approved by the FDA in 2010 to treat bype 2 diabetes. When Victoza was approved, the FDA noted that animal data suggested a rare type of thyroid cancer, known as medullary thyroid cancer, was linked to the use of Victoza. According to the FDA, studies in mice and rats showed liraglutide was linked to the development of tumors in the thyroid gland, "especially at doses that were 8-times higher than what humans would receive."

As a result, the FDA requested a Risk Evaluation and Mitigation Strategy for Victoza and further required a five-year epidemiological study of Victoza.



Victoza Cancer Legal Help

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Last updated on Jun-3-14

VICTOZA CANCER LEGAL ARTICLES AND INTERVIEWS

Victoza: EMA Moving Forward While FDA Idles Over Victoza and Cancer
Victoza: EMA Moving Forward While FDA Idles Over Victoza and Cancer Washington, DC: While cautious concern still exists with regard to Victoza side effects, the European Medicines Agency (EMA) has begun the process of actually allowing for expanded use of Victoza in the areas of the world governed by the EMA [READ MORE]

Opinions Split on Victoza
Opinions Split on Victoza Washington, DC: Concerns about Victoza side effects, including a reported possible link between Victoza and cancer, have led to some critics requesting the type 2 diabetes drug be taken off the market. Not all studies, however, have confirmed the risk of cancer in patients taking Victoza [READ MORE]

FDA Plays Down Victoza Cancer Concern, but Plaintiffs Beg to Differ
FDA Plays Down Victoza Cancer Concern, but Plaintiffs Beg to Differ Washington, DC: The US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) may have agreed that there isn’t a lot to talk about with regard to Victoza side effects. To wit, the two health regulators have parked any provocative concern over pancreatitis and precancerous changes to the pancreas with regard to Victoza and other drugs in the incretin mimetics class. But that hasn’t stopped lawsuits brought by plaintiffs alleging Victoza and other similarly classed drugs did in their pancreas. And now the FDA is investigating another drug in the class over a concern for heart failure [READ MORE]



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