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Reglan Side Effects
Reglan (metoclopramide) is used to treat Gastroesophageal Reflux Disease (GERD), acid reflux disease and heartburn. While many Reglan side effects are minor, some patients have experienced serious side effects, including Tardive Dyskinesia. Some metoclopramide side effects, such as Neuroleptic Malignant Syndrome, can be fatal while others are permanent. Also at issue is the prescribing of Reglan for off-label uses, meaning for conditions that Reglan is not approved by the Food and Drug Administration to treat. generic form of Reglan, Metoclopramide, may be involved in Reglan litigation.Both the brand name drug, Reglan, and the
Reglan and Tardive DyskinesiaReglan (metoclopramide) is used to treat Gastroesophageal Reflux Disease (GERD), heartburn and acid reflux disease. Although most side effects are temporary, a side effect that allegedly can be permanent is Tardive Dyskinesia.
Tardive Dyskinesia is characterized by repetitive, involuntary, purposeless movements such as grimacing, tongue protrusion, lip smacking, puckering and pursing, and rapid eye blinking. Rapid movements of the arms, legs and trunk may also occur. Impaired movements of the fingers may appear as though the patient is playing an invisible guitar or piano.
The FDA has only approved Reglan for short term use (4 to 12 weeks), but approximately 30 percent of patients are being prescribed the medication for 12 months or longer; long-term Reglan use has been linked to Tardive Dyskinesia.
Tardive Dyskinesia is a horrible, devastating syndrome that can last a lifetime. It affects victims physically, mentally, socially, emotionally and vocationally.
Reglan Black Box WarningIn February, 2009, the US FDA announced that Reglan would now carry a black box warning, alerting patients about the risk of Tardive Dyskinesia when Reglan is used for longer than three months. Prior to that, Reglan's labeling mentioned Tardive Dyskinesia as a possible side effect but claimed the occurrence was rare.
Reglan Black Box Warning for Tardive Dyskinesia:
Off-Label Reglan UseReglan was approved for short-term use to treat GERD, acid reflux disease and heartburn. However, some patients are prescribed Reglan for longer-term use, 12 months or longer. Meanwhile, other patients are prescribed Reglan for uses not approved on the label. These include treatment of pregnancy-related nausea and morning sickness, lactation stimulation and treatment of migraine headaches.
Off-Label Reglan is sometimes prescribed to treat:
- Pregnancy-related Nausea
- Morning Sickness
- Lactation Stimulation
- Migraine Heachache with Nausea
Some forms of Reglan, such as the injectable version, are approved to treat nausea brought on by cancer chemotherapy. However, other uses of Reglan to treat cancer-related nausea, such as for radiation nausea, or the use of oral Reglan to treat chemotherapy nausea, may be off-label uses. Additionally, as with Reglan for chemotherapy induced nausea, Reglan is sometimes used to treat post-operative nausea.
Although off-label use of a drug is not illegal, it is not recommended because studies have not proven the drug to be safe and effective for such uses.
Other Reglan Side EffectsOther serious Reglan side effects include Neuroleptic Malignant Syndrome (NMS), which is often fatal. Patients can develop NMS after only short exposure to a drug. NMS symptoms include high fever, sweating, unstable blood pressure, stupor, muscular rigidity and autonomic dysfunction. Symptoms can appear within the first 2 weeks of taking a drug.
Further side effects include Parkinsonism, characterized by slight shaking, body stiffness, difficulty moving and difficulty keeping balance. Patients with Parkinson's disease may experience a worsening of Parkinson's symptoms when they take Reglan.
Reglan Side Effects Legal HelpIf you or a loved one has taken Reglan and subsequently suffered from tardive dyskinesia or other side effects, please click the link below and your complaint will be sent to a lawyer who may evaluate your claim at no cost or obligation.
Last updated on Apr-19-10
REGLAN LEGAL ARTICLES AND INTERVIEWS
Closing Loophole Would Help Generic Reglan Tardive Dyskinesia Patients
New York, NY: Months after the Supreme Court ruled that generic drug companies do not share the same level of responsibility as their brand-name counterparts when it comes to updates of their product labeling, a noted New York publication continued to push for the generic labeling loophole in the law to be closed. Such a response would benefit patients suffering from Reglan tardive dyskinesia, regardless of whether or not the adverse reaction was triggered by a generic, or name brand Reglan [READ MORE]
Your Reglan Lawsuit: Is Time Running Out on You?
Washington, DC: Reglan side effects—some of them extremely serious and debilitating—have resulted for many in a Reglan lawsuit, as plaintiffs attempt to pursue compensation for a life and lifestyle negatively, and often permanently, impacted by taking the drug as prescribed. Reglan tardive dyskinesia, for example, can prevent one from doing his or her job safely. The involuntary shaking associated with the condition can also be socially embarrassing—especially for a young person [READ MORE]
Supreme Court Rules on Generic Reglan against Tardive Dyskinesia Victims
Washington, DC: The Supreme Court ruled today, in a 5-4 decision, that generic drug companies do not share the same level of responsibility as the makers of brand-name drugs to update their product labeling. The ruling effectively ends two separate lawsuits brought by two women who claim they suffered severe medical complications from using a generic form of Reglan. [READ MORE]
MORE REGLAN LEGAL NEWS
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I did not know that Reglan was a short-term drug. I was on it for 7 years. I was suddenly taken of it after seeing a gastroenterologist for GERDS symptoms. Within 3 days I developed Tardive Dyskinesia and loss of my voice. Have seen two specialist and don't know if symptoms will ever resolve.
I took Reglan/Metroclopramide for over 3 years and the last few months it was doubled up on me. I was a zombie, wanted to sleep all the time, hot flashes, depression, weak, lost 15 pounds.
I have had Tardive Dyskenesia for about 10 years, I have a stomach disorder that I have taken many different drugs for, including reglan.
I was prescribed Reglan (both IV and pill form) for excessive nausea and vomitting during my first pregnancy. While on the drug, I experienced HORRID episodes of RLS. After receiving this drug 4-5 times it was diagnosed that I was "allergic" to it, so it was no longer given to me, and it is noted in all my charts that I am allergic. The thing is, it has been four years since the last time I was given Reglan, and I still experience terrible restless legs. It is to the point where sometimes I have trouble sleeping. Once in awhile it will happen in my hands too. I recently saw a TV commercial for others who have experienced this and I decided to research a bit and I found this website.
I am a long time migraine sufferer. Unfortunately, doctors seem to be at a loss for treating my migraines. When prescribed Reglan and Topamax I began to develop tardive dyskinesia. Doctors dismissed my allegations as nonsense and a result of my migraines. I looked as if I was having a stroke as it seemed to only cause problems on my left side. Although I stopped Reglan, I still have weakness on the left side of body, and occassionally will continue to have facial paralysis. I was never able to put a name to what this was until now.
When I close my eyes to sleep (or even just sitting around) the eyelids start rapidly twitching. I do also have occasional leg twitching. The eyelid twitching makes it almost impossible to fall asleep without medication.
I have parkinson's. Because of this, I have trouble digesting food. I was sent to a gastrologist who put me on reglan. I was on it for 8 months and decided to stop taking it because I noticed that my rigidity had gotten worse. I suffer from spasticity anyway and this medicine seemed to aggravate it. No one with parkinson's should take this medicine.
Stiffness of body, movements became robotic like, slowed thinking, problems speaking, problems caring for myself, and eyes became unfocused, developed a tremor in my hands. I walked with my arms by my side with elbows crooked, lower arms straight out and my hands open with thumbs up. I became so anxious my sleep was disrupted and I felt like I was dying.
The mother of the my six month old grandchild that I have had custody of since 2/11/2009 was given Reglan for treatment of acid reflux while pregnant. The baby presents constant leg jerking and other uncontrolable movements not normal in a 6 month. I believe that this medication crossed the placenta and caused this as I have never seen this type of behavior in an infant.
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