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Lisinopril Liver Damage
Generic Lisinopril, often misspelled as linisiprol, linisopril or lisiniprol, is sold under the brand names Prinivil and Zestril. Lisinopril is used to control high blood pressure and treat congestive heart failure, and belongs to a class of drugs called angiotensin-converting-enzyme (ACE) inhibitors. Lisinopril combined with hydrochlorothiazide, is marketed by a number of pharmaceutical companies to treat hypertension (high blood pressure). Hydrochlorothiazide is a water pill (thiazide diuretic) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Recent findings in patients taking lisinopril indicate a risk for lisinopril liver damage or lisinopril liver failure.
Lisinopril Liver Damage
Most complaints stem from people who were prescribed lisinopril combined with hydrochlorothiazide. Because most liver damage complaints have occurred within the last few years, it is speculated that there may be a generic formulary now marketed without clinical studies. Lisinopril was the third ACE inhibitor introduced to the market in the early 1990s.
Lisinopril and Liver Transplant
Two recent cases have confirmed that lisinopril directly caused the destruction of the patient’s liver and in each case it was nearly fatal: Both patients required liver transplants. Both lisinopril users are young adults in their 30s with no prior history of liver problems and they both took lisinopril for a relatively short time (one of the victims, a young and healthy mother, took it for 6 weeks). Their hospital and medical records and medical personnel attribute causation of liver destruction to lisinopril.
According to a 1995 report by PubMED, chronic hepatitis and liver damage can be caused by lisinopril.
To date, the lisinopril product labeling indicates that it may cause liver damage and not liver failure. ( Lisinopril does contain a black box warning which states that ACE inhibitor drugs that act directly on the renin-angiotensin system can cause injury and even death to a developing fetus when used during the second and third trimesters of pregnancy.)
According to one manufacturer, if the liver cannot process lisinopril, it is simply flushed out through the kidneys, but in some people the medication is being stored in the liver.
Although acute liver failure (ALF) mostly affects young people who are otherwise healthy, it can occur in people of all ages. A phD in pharmacology has confirmed that Lisinopril “contains all the ingredients that makes it hazardous and it has the ability to destroy the liver in young adults.” However, it is possible that the drug can destroy anyone’s liver—at any age.
ALF encompasses both fulminant hepatic failure (FHF) and subfulminant hepatic failure (also known as late-onset hepatic failure). FHF usually occurs within eight weeks of the onset of symptoms in a patient with a previously healthy liver, while subfulminant hepatic failure typically occurs in patients with liver disease for up to 26 weeks before the development of hepatic encephalopathy—a worsening of brain function that occurs when the liver is no longer able to remove toxic substances in the blood.
Lisinopril is just one of more than 900 drugs, toxins and herbs that can cause liver injury, making drug-induced hepatic injury the most common reason to withdraw an approved drug.
Lisinopril Liver Damage Symptoms
Signs of such liver damage include dark urine, fatigue, jaundice, nausea and stomach/abdominal pain. Read more: lisinopril side effects for more information on lisinopril side effects and precautions.
Attorneys have been contacted by lisinopril consumers nationwide reporting liver damage or failure and they are currently reviewing those medical records. If you have experienced Lisinopril liver damage or failure, you should seek legal help. Lisinopril claims allege that the manufacturer has designed and distributed a dangerous drug without appropriate testing and without giving all the warning signs to doctors and patients.
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Last updated on Apr-3-12
LISINOPRIL ARTICLES AND INTERVIEWS
Lisinopril Suspected As Cause of Death
Buffalo, NY: A negative impact on liver function is not amongst the more common Lisinopril side effects. Be that as it may, some patients taking the oft-prescribed treatment for high blood pressure have experienced Lisinopril liver damage, including a woman who posted to a blog in late 2010 that her (acute liver failure) was caused "by a blood pressure medicine called Lisinopril," Jennifer Roberts wrote in October of that year, by way of a post to the blog transplantcafe.com. "(Lisinopril) shut my liver down within six weeks. [READ MORE]
Seattle, WA: Chances are, you know someone who is on a gluten-free diet to help treat digestive problems. This diet is fast rising in popularity, and at the same time, so is an increase in prescriptions for medications such as Lisinopril. But Lisinopril comes with serious side effects, including liver damage and digestive-tract problems, such as celiac disease and irritable bowel syndrome. It would be interesting to find out how many Lisinopril consumers believe they are wheat-intolerant and are on gluten-free diets [READ MORE]
Las Vegas, NV: Many prescription drugs are as common as aspirin; it's no wonder that many consumers don't read warning labels or consider that a medication could be associated with side effects. Take Lisinopril, for instance. It is one of the most widely prescribed drugs in the US, and it also has the potential to harm a lot of people [READ MORE]
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