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Stevens Johnson Syndrome

Stevens Johnson Syndrome (SJS) is a life-threatening illness, usually caused by a severe allergic reaction to a medication. Also known as Erythema Multiforme, Leyll's Syndrome, and in its later stages, Toxic Epidermal Necrolysis (TEN), SJS causes large areas of the skin to become detached and lesions to develop in the mucous membranes. Infections caused by the loss of skin or scarring of major organ systems can lead to debilitation or death.

SJS Medications
Symptoms of Stevens Johnson Syndrome
Who Is at Risk?



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Stevens Johnson Syndrome (SJS)

Pharmaceutical manufacturers are aware of the risks associated with their drugs, yet proper warnings are for the most part inadequate. Many over-the-counter (OTC) drugs such as Ibuprofen—found in Advil and Motrin—have been linked to Stevens Johnson Syndrome (SJS). Without adequate warnings, patients who develop SJS may continue to take the SJS-causing drug, which could lead to life-threatening TEN.

SJS Medications

SJS is caused by almost any medication, including antibiotics, anticonvulsants, sedatives and painkillers. The leading causes of this disease are the following medications:
  • Ibuprofen (Advil, Children's Advil, Motrin, Children's Motrin and Nuprin)
  • Ketek, an antibiotic
  • Dilantin, an anticonvulsant
  • COX-2 inhibitors Bextra (Valdecoxib),Vioxx (Rofecoxib), Celebrex (Celecoxib), and Non Steroidal Anti-Inflammatory Drugs (NSAID's) including Daypro (Oxaprozein)
  • Non Steroidal Anti Inflammatory drugs such as Feldene (Piroxicam), Naproxen (Aleve)
In May, 2006 the FDA updated several prescription and over the counter (OTC) medications with a warning label as a result of increased risk of developing Steven's Johnson Syndrome. The following drugs had either a new warning regarding SJS or additional wording:
  • Tolectin 600 Tablets (Tometin Sodium)
  • Tolectin DS Capsules (Tometin Sodium)
  • Advil Allergy Sinus Tablets (200 mg ibuprofen / 30 mg pseudoephedrine HCI / 2 mg chlorpheniramine maleate)
  • Advil Cold & Sinus Tablets (200 mg ibuprofen / 30 mg pseudoephedrine HCI)
  • Advil Liqui-Gels (200 mg ibuprofen capsules)
  • Advil Migraine Capsules (200 mg ibuprofen)
  • Children's Motrin Chewable Tablets (50 mg ibuprofen)
  • Motrin Junior Strength Chewable Tablets (100 mg ibuprofen)
  • Motrin Cold & Sinus Tablets (200 mg ibuprofen / 30 mg pseudoephedrine HCI)
  • Motrin IB Tablets (200 mg ibuprofen)
  • Motrin Infants' Drops (50 mg / 1.25 mL ibuprofen oral suspension)
Symptoms of Stevens Johnson Syndrome

sjs Stevens Johnson Syndrome can begin with a fever, sore throat and headache and over a few days (or sometimes even minutes) can turn into skin lesions and blisters. It generally affects the mucous membranes of the mouth, throat, internal organs are affected.

As Stevens Johnson Syndrome evolves, the skin literally sloughs off in sheets. Patients are typically treated in a hospital's burn unit. If the skin lesions become infected, or the patient develops lesions in the lungs, it can cause death (which results in about 15-20 percent of cases).

This horrific and painful disease frequently causes blindness. Recognizing early symptoms of SJS and providing prompt medical attention are the most valuable tools to minimizing long-term damage.

Who Is at Risk?

Allergic drug reactions cause more than 100,000 deaths among patients in the United States each year.

Those patients most likely to develop Stevens Johnson Syndrome are extremely allergic to antibiotics or painkillers like Ibuprofen. Most cases occur in adults between the ages of 20-40 years, but SJS has been diagnosed in children as young as three months old. Anyone who takes prescription or over-the-counter (OTC) drugs runs the risk of developing allergic reactions and developing serious health problems like Stevens Johnson Syndrome.

Drug companies who place profit above people must be held accountable for their negligence and the damage they cause to innocent victim's lives. Our Stevens Johnson Syndrome lawyers have helped thousands of clients win millions of dollars from the manufacturers and suppliers of unsafe drugs and products.


Register your Stevens Johnson Syndrome Case

If you or a loved one has suffered from Stevens Johnson Syndrome, you may qualify for damages or remedies that may be awarded in a Stevens Johnson Syndrome class action or lawsuit. Please click the link below to submit your Stevens Johnson Syndrome complaint to an attorney who will review your claim at no cost.


Last updated on Mar-9-10

STEVENS JOHNSON SYNDROME (SJS) ARTICLES AND INTERVIEWS

"I Survived SJS/TEN"
"I Survived SJS/TEN" Morrisville, PA: "I took Bactrim and Motrin for a blood infection for 30 days before the meds caused Stevens Johnson Syndrome or SJS," says Justin. "The day after Thanksgiving I woke up in the middle of the night with a bunch of blisters in my mouth, all over my tongue and my lips—I was choking on the fluid. I tried to sleep it off but when I woke up I had more blisters, a high fever, shivers, vomiting and was very fatigued. I was only 22 years old, I work out all the time, take vitamins and really look after myself—what was happening to me?" [ Read More ]

Doctor's Quick Diagnosis May Have Saved Life of Patient with SJS
Doctor's Quick Diagnosis May Have Saved Life of Patient with SJS Detroit Lake, MN: A Minnesota boy diagnosed with Stevens Johnson Syndrome (SJS) may owe his life to the speedy diagnosis of a local doctor, according to his mother. [ Read More ]

Health Canada Warns Accutane Patients About SJS
Health Canada Warns Accutane Patients About SJS Ottawa, ON: A number medications have been linked to the serious skin disease Stevens Johnson Syndrome (SJS). This week the Canadian government added one more potential medicinal hazard to the list. [ Read More ]


STEVENS JOHNSON SYNDROME (SJS) SETTLEMENTS

82 Year Old Awarded $6 Million in SJS Lawsuit


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