Premarin is an estrogen-only hormone replacement therapy (HRT) used to treat the symptoms of menopause. Premarin is the most popular HRT drug, and one of the most prescribed drugs in the world. Premarin is typically prescribed for women after a hysterectomy. Studies have linked use of Premarin (conjugated estrogens) to the following serious side effects: Stroke, Ovarian Cancer, Lupus, Scleroderma, and Gallbladder Cancer.

The National Institutes of Health recently stopped a trial of women taking Premarin estrogen replacement therapy after finding the drug not only failed to reduce the risk of heart disease but actually increased the possibility of strokes.

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