Humira Side Effects

Humira (known generically as adalimumab) has been linked to serious Humira side effects, including an increased risk of a rare but usually fatal form of cancer. As a result of this increased risk, the US Food and Drug Administration (FDA) issued a warning about the risk of Humira cancer, especially in adolescents and young adults. Humira, which is made by Abbott Laboratories, is used to treat Crohn's disease and symptoms of various forms of arthritis.

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Humira Infection

Humira is in a class of drugs known as tumor necrosis factor (TNF) blocker. Other drugs in the TNF-blocker class include Enbrel and Remicade. Humira can decrease a patient's ability to fight off infections, leaving the patient at risk of developing serious infections including tuberculosis and infections caused by viruses, fungi or bacteria. Some patients have reportedly died from these infections, which can spread throughout the body.

Humira Cancer Risk

In addition to an increased risk of serious infections, the FDA issued a warning in April 2011, that some patients, mainly adolescents and young adults who were taking Humira for Crohn's disease, could be at an increased risk of a rare cancer called Hepatosplenic T-Cell Lymphoma (or HSTCL). HSTCL is a cancer of the white blood cells, is aggressive and is usually fatal, according to the FDA. This risk was increased when patients used the TNF-blocker drugs such as Humira with either azathioprine and/or mercaptopurine.

In August 2009, the FDA announced that an analysis of TNF-blocker medications showed an increased risk of lymphoma and other cancers associated with the use of those medications in children and adolescents. That discovery resulted in an update of the boxed warning for TNF-blocker medications.

Humira Lawsuits

A woman who took Humira for rheumatoid arthritis during a clinical trial filed a lawsuit against Abbott Laboratories alleging her use of Humira resulted in lymphoma. The plaintiff alleges she began Humira in early 2005 and was told she was at an increased risk of tuberculosis. She reportedly stopped taking the drug when she was diagnosed with lymphoma.

Meanwhile, a lawsuit was filed against Abbott Laboratories in April 2011, alleging that use of Humira caused a woman to experience permanent nerve damage in her feet, after she took the drug to treat Crohn's disease. The lawsuit alleges that Abbott knew about the risk of peripheral neuropathy before it marketed the drug for the treatment of Crohn's disease.

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Last updated on Jun-13-11

HUMIRA ARTICLES AND INTERVIEWS

Humira Medication Not for Everyone

San Francisco, CA: It was just a couple of months ago that Humira was the subject of a warning by the US Food and Drug Administration (FDA) with regard to the potential for Hepatosplenic T-Cell Lymphoma, a rare cancer involving white blood cells. However, it was 18 months prior to the release of the warning in April of this year that the FDA first revealed an analysis of tumor necrosis factor blockers, such as Humira, and adverse reactions that could ensue. These particular Humira side effects came to light in August of 2009 [READ MORE]

Humira Side Effects Lawsuit Filed

Helena, MT: A lawsuit has been filed alleging Humira side effects caused permanent damage to a patient who took Humira medication for Crohn's disease. The Humira lawsuit claims Abbott Laboratories knew about the risks associated with its medication, but did not adequately warn patients about that risk. This lawsuit is separate from another lawsuit alleging patients faced Humira cancer risk from using the medication [READ MORE]