Posts Tagged ‘ Eli Lilly ’

Zyprexa – Making Lemonade out of Lemons

February 1st, 2010. By LucyC

Zyprexa...making lemonade out of lemonsYou may recall a study that hit the news last October, published in JAMA, on the use of four new generation antipsychotics—Zyprexa, Risperdal, Abilify and Seroquel—used to treat schizophrenia and bipolar I disorder in adults and adolescents. Long story short—it was not a good news story for the kids on these drugs, and most especially kids on Zyprexa.

Why not? Weight gain, increases in triglyceride levels and associated risks for diabetes and cardiovascular disease. 

The average weight gain over the 12 week study period was the highest for Zyprexa—17 pounds. You’d be hard pressed to gain that kind of weight sport-eating your way through the holidays… 

Suffice to say an editorial in JAMA called the study results “timely and sobering,” suggesting that the new generation of antipsychotics are not all they’re cracked up to be. “These results challenge the widespread use of atypical antipsychotic medications in youth,” University of Washington, Seattle child psychiatrists Christopher K. Varley and Jon McClellan wrote. 

Well, maybe not. On January 29th, nearly three months after the study was published, the Food and Drug Administration (FDA) issued a warning to doctors regarding prescribing information for Zyprexa, but it’s not exactly strong…here’s part of the FDA Safety warning: 

“Section 1, Indications and Usage: When deciding among the alternative treatments available for adolescents,

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7 Game-Changing Settlements of 2009

December 15th, 2009. By Kristine B

We’re in the countdown to year-end and looking over some of the more impactful settlements LawyersAndSettlements.com has covered over the past year. When we’re talking impactful, everyone around here has an opinion—so we had to throw in some criteria. To get the nod for impact, a settlement had to be one of two things: 1. High dollar value; or 2. Precedent-setting—or at least have the potential to influence similar cases to follow. (Sounds siSettlement moves with impact in 2009mple, but you try getting Stephen, John, Jaime, Michelle and Ben to settle in on just 7 settlements with just those criteria…) So here we go…7 game-changing settlements for ‘09…

1) Family takes on GlaxoSmithKline  

Michelle David filed a lawsuit against GlaxoSmithKline, alleging the company’s antidepressant, Paxil was responsible for her son’s birth defects. David said she had taken Paxil while pregnant and was not aware of the potential side effects. GlaxoSmithKline said that birth defects occur in between three and five percent of all live births, regardless of Paxil use. 

A jury found, in a 10-2 decision, that GlaxoSmithKline’s officials were negligent in failing to warn David’s doctor about the risks of Paxil. The jury also found that Paxil was a factual cause of the little boy’s heart problems. David was awarded $2.5 million.

Why it’s impactful:There are 600 or so lawsuits alleging Paxil caused birth defects waiting in

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Lawsuits Needed Against Prescribing Quacks

April 24th, 2009. By Evelyn Pringle

On April 21, 2009, the Miami Herald reported that a 7-year-old boy in Florida, Gabriel Myers, had committed suicide by hanging himself with a detachable shower head in a bathroom of the foster care home he was placed in three weeks earlier.

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