Houston, TX: Lisinopril, used to treat hypertension, congestive heart failure and heart attack, is associated with many side effects including liver damage. Beverly was diagnosed with angioedema (which can be life-threatening) as a direct result of Lisinopril, according to her hospital doctors.
Beverly started taking Lisinopril in 2001 when she was diagnosed with hypertension. "I took it for a few years and felt OK, but a few years later my blood pressure was out of control," says Beverly, "so my physician's assistant prescribed Lisinopril 40mg, up from the 10mg I was taking." At that time Beverly mentioned her swollen gums, thinking it might be a Lisinopril side effect, but the assistant wasn't concerned. "My blood pressure didn't drop, but the doctor dropped the Lisinopril back to 10mg—I don't know why.
"About a year later I had difficulty breathing but chalked it up to a summer cold," Beverly adds. "One Friday night my blood pressure soared so much that my friend took me to ER. I was released Sunday afternoon—the doctor didn't notice the swelling of my lips, gums, and tongue; he ordered me to continue the Lisinopril, but all my symptoms were getting progressively worse. The following Friday night I was just getting out of the shower when I called 911—I could hardly breathe, I was gasping for air. I met the paramedics in the street and just about fell into the ambulance.
"An allergy specialist saw me and took me off the Lisinopril immediately; he told me that this med was causing the swelling and my breathing problems, so thanks to Lisinopril I was hospitalized for a week and racked up about $23,000 in medical bills." (Beverly doesn't have health insurance so this has also caused her severe financial problems.)
Beverly was diagnosed with angioedema, a condition that involves the rapid swelling of the face, lips, tongue, throat, arms or legs. It is an allergic reaction; although mild cases may not require medical treatment, severe cases can lead to life-threatening problems, such as difficulty breathing. According to the Western Journal of Medicine, severe angioedema and respiratory distress can be caused by Lisinopril.
"I was put on a different hypertension med and felt well enough to go home," says Beverly. "I tried talking to the clinic administrator where I was first prescribed Lisinopril but nobody would talk to me. I changed doctors but she advised that I go back on Lisinopril, despite me telling her its side effects. Needless to say, I talked her into prescribing another drug. I still have trouble breathing and often have inflammation in my ankles, feet and legs—I'm certain all these symptoms are caused by Lisinopril. I don't know whether they are long-term side effects or not, and naturally I wonder if they will get any worse."
Beverly is hopeful that she has a case against the drug manufacturer and that an attorney will review her claim.
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Posted by Lee Mason
I have diabetes and take a pill to control it. November 1st 2014 I went to my doctor for a check up,and the PA prescribed me Lisinopril 5 mg to protect my kidneys because of the diabetes . Never taken any blood pressure medicine before. After the 2nd week my body started to feel real funny,numbness and tingling on left side,fatigue upon standing and exhaustion,and some tightness of chest. On November 13th I really got sick from medicine and stopped taking it,still had complications. On November 13th I decided to go to the ER and I was admitted. Negative blood work,MRI,EKG,Sonograms. Doctors dodge around possible effects of lisinopril made me ill and released me 24 hours later, with no definite reason,and just prescribe me aspirin. Are doctors afraid to tell patients the real dangers of this drug???
Posted by Troy
Lisinopril gave me Peyronie's disease. Please help. I am depressed over this and it has ruined my sex life. I have been taking lisinopril for over 10 years at 40mg per day. When I told my dr about the side effect, she laughed and said it was a rare side effect. No one told me of this possible side effect and it was only through searching for the causes of a curved penis that I stumbled on this side effect. I am angry, depressed and at a loss of what to do. I feel used and lied to. My sex life has been damaged and I have been told the damage to my penis is not reversible. Please help.
Posted by CR
took Lisinoprill-HCTZ for 4 months. Tongue swelled up so much I couldnt close my mouth, vomiting and severe (I mean severe) stomach pain. Ended up with pancreatitis and spent 9 days in the hospital. Every doctor that saw me said this drug is notorious for mouth swelling and acute pancreatitis
Posted by evelyn bellamy
I have been taken Lisinopril for years not knowing how bad it is. I have the swelling in my face , rash, panic attack, and dry cough. It' s scary what can I do?
Posted by rhonda mclain
My husband has been taking lisinopril for 5or 6 years now..today he had to go to md..his face and lips are swollen and has rash with welps on his back..has had a cough ever since he has been taking this med...and he always feels tired and has back pain ....dr took him off lisinopril she said this was the cause of the problems he was having...
Posted by Dora Campbell
I was in coma for 3 days from taking the Lisinopril. The Doctor said do not take that product again.
Posted by Cindy V
My husband took Lisinopril for 6 months and he has had 2 episodes of his tounge and lip swelling. The Dr. took him off of this med. 6 months ago and now for the past 2 weeks has had 2 more episodes of angioedema. How long does it take for this drug to get out of your system and when will these side effects STOP?
Posted by Dorothy Stallworth
I am a nurse and have been taken Lisinopril for years. I had not noticed any side effects but woke up this morning with severe facial swelling. I had noticed for a few days that at night my bottom lip felt heavy and wondered was I having a little reaction to some watermelon. It was not bad enough for me to check out. This morning due to the tightness in my facial and throat, I went to the bathroom to see what was going on. Was I surprised to see such severe swelling! I immediately started taking Benadryl but no relief. After a few hours, I decided that I needed further treatment. The swelling in the face was affecting my swallowing. I went to an urgent care center and received 2 Epi pen injections and a Benadryl injection. I would not recommended waiting to anyone. It was dangerous for me because u can't give CPR to yourself.
Posted by Faye Pelzer
I started taking lisinopril 3 to 4years ago. Since then I have had 3 bouts of severe face swelling. I recently was rushed to the hospital with severe lips, face, tongue, and throat swelling. I was diagnosed with Angioedema that was cause by the Lisinopril. I was told to stop taking the medication right away. I thought I was going to die. I could not breath. I have severe facial scarring from the rashes on my face which has lead me to severe depression. My doctors did not know what was causing the swelling. I have an appointment to get allergy testing. I cannot believe this medication is still on the market.
Posted by Francis Efaw
Seems I'm not the only one to have issues with this medication. The symptoms others have mentioned have also affected me. First I was on Triamterene and then I was also put on Lisinopril @ 40 MG right from the start. I was told to take them both at the same time. I had a rash develop on both shins and it did itch. The doctor tried a couple of treatments to get rid of the rash. I was prescribed a tablet steroid and also a prescription corticosteroid cream. Both treatments failed miserably. Due to the itching from the rash I have scars now. Another doctor told me he felt the Triamterene was the blame for the rash. It gets much worse though - between those blood pressure medications it caused my blood pressure to drop dangerously low! I can remember 87/56. Indeed I was dizzy. I was sitting on the couch and I knew I was passing out. I called the pharmacy for advice. They told me my blood pressure was too low and I should call 911. Well, I didn't want to do that so I just laid down on the couch with my legs elevated, (propped up on the wall). I don't know if I fell asleep or passed out. Another instance was when I was walking in my house and all of a sudden I passed out and hit the floor. That was awful. I managed to break three bones in my face according to a CT scan. The worst was I was driving home from work and I almost made it home. I was only about five homes from my house and I passed out cold while driving. I crashed into a truck that was parked on the street. So as you all can imagine I stopped taking the Triamterene and the Lisinopril immediately and I will never take them again - not ever! I have been monitoring my blood pressure every single day and take three readings every single day and come to find out I do not need to be on blood pressure medicine at all. So, that irritated me. Now I have some issues going on with both eyes. Just had my third comprehensive eye exam yesterday. The doctor told me I have one nevus in my left eye and two or three in my right eye. I saw the images taken. This is only a little unsettling, however they are no different than a nevus, (mole) on the skin. They can turn into melanoma. A condition I am way too familiar with. Unfortunately there is no way to safely remove melanomas from the inside of the eyes. I do not know if the medications could be responsible for that particular condition, but I'm carefully researching. The eye doctor asked me the strangest question yesterday. She wanted to know if I had had a colonoscopy so I told her that I did have one and a polyp was found, removed, biopsied and the results were benign. The eye doctor said I should have another colonoscopy. That is what I don't understand. What does a colonoscopy have to do with the nevus in both of my eyes? The eye doctor told me she was sending this information to my primary care provider and I have an appointment with my primary care doctor in three days. We will discuss this. Bottom line, if you can avoid Lisinopril and/or Triamterene I strongly urge you to avoid them. Throw away the salt and use a salt substitute, such as a product called "No Salt," but don't use the salt substitute if you are taking potassium sparring diuretics or any blood pressure medication. That is dangerous and it can be potentially fatal. After you ditch the salt shaker it's also advisable to get groceries with little to no salt added. If you smoke, try to cut down or quit, if you're overweight try to lose a few pounds. I do not believe in taking medication to offset our food and spice consumption. Best wishes to all. We can beat this and more than likely we can beat this without medicine.
Posted by Amy Richardson
Have had swelling tounge- horrible uncontrollable coughing and terrible itchy skin and swelling all over my body!! My tongue swoll so badly it almost cut off my breathing!!! Do not take this drug!! It is dangerous and wrong to prescribe to anyone!!
Posted by Randy Chaney
I have been taking lisinopril for over 4 years. Last week I woke up with swelling on the left side of my face but it went away by the afternoon. This week I experienced swelling on the right side of my face and my lips swelled to three time the normal size. By the afternoon hours it had spread to my left side. The next morning my left eye was swollen and my left jaw was swollen. My hands and feet began to swell as well. You know how we men are about going to get this stuff checked out and my wife urged me to go to the doctor. He immediately took me off of the lisinopril and gave me a steroid shot. Today my eye is still swollen but the rest of my face has gone back to normal but I now have a rash developing. The doctor couldn't tell me why this happened after 4 years with no problems. He said it could be because I had lost 40 lbs and my blood preasure was looking better. I hope I can stay off ALL BP medicine now.
Posted by Alma Gomez
I had been taking Prinizide (lisinopril/hctz) for about a year on May15 I was at work (luckily I work at a Hospital), I was feeling fine but after lunch I started noticing my tongue started swelling & I went back to work & 5 minutes later I was having a hard time moving my tongue when talking, the pharmacist gave me benadryl to see if that help but it didn't so I went to ER the PA quickly told me to stop taking my Blood pressure medicine, they gave me all the antihistamines they had more Benadryl, Zyrtec, etc.. by this time I had a hard time drinking water or squalling my own saliva they Put me in a room and gave me a shot of epinephrine the next time they came & check on me I couldn't close my mouth because my tongue was so big coming out of my mouth & had a hard time breathing the Dr. Told me he had to call ENT & Anesthesia in a couple of minutes my room was full of Drs & they told me they were going to try to put a tube down my nose but if that was not possible they were going to have to do a trachonomy, they took me into The OR to try to put a tube down my nose, I was vomiting & at the same time trying to breath I felt like I was drowning & I passed out, I went into a respiratory arrest when I woke up I was in ICU hooked to a ventilator & had to stay there for 3 days, I am so lucky to be alive, if you have food allergies with history of Angioedema don't take Lisinopril it can kill you!!
Posted by Lena
I have taken this pill for only 2 days and my legs and feet are visibly swollen and tingling after only 2 days of this medication. I am stopping this medication and going to be monitoring myself for the next few days. This medication is the only new med I have introduced to my system so I am certain it is the cause. If it doesn't clear up I will call my doctor Monday or go to the emergency room if necessary. I googled the medication after I noticed the symptoms. I am very uncomfortable and hope this medication gets out of my system soon since I have note taken it very long.
Posted by amanda
Last week, my doctor put me on 10mg lisinopril. The first 3 days I had nagging headaches and nausea but wasn't horrible. Day 4 I woke up in the morning with horrible cramps in my right leg. It got better as the day went on. Day 5 I woke up with both legs , knees, thighs , ankles everything but my feet, in horrible pain and my low back is killing me.
I called my doctor and they said stop taking the lisinopril. I'm in horrible pain now and I hope this junk leaves my body ASAP. I took a pain killer last night and I NEVER take them. It hurts so badly. This drug is horrible. I'm 32 and have a toddler to chase and I can't even put her on the potty.
Posted by ARIE
I was rushed by fire rescue on 4/4 to the E.R. My arms and legs were numb and tingling. They thought I was having a stroke. MRI and CT scan were negative for stroke. They said it was my Potassium was low and gave me 4 huge potassium pills and sent me home the next day. I kept taking the Lisinopril 10mg, I kept feeling tingling in my hands and lightheadedness. Today I felt like I was going to pass out and again the tingling and weakness in my arms, and also short of breath. I came home crying. My husband thinks it is all mental and told me to relax. I then started reading about other people with the same symptoms. As I type this I am dizzy and have trouble breathing and concentrating. I am drinking a lot of water trying to get it out of my system.
Posted by RONALD OUELLETTE
Been on lisinopril for about 20 yrs. All sudden october 4, 2011
broke out with itching all aver my body to the point of having
dermography. Where you can write your name anywhere on my skin and it would swell and raise so you could read whatever word you would write. That same day extreme ringing of the ears started in the evening. Doctor said I was allergic to something. I knew it was Bs because this was every day all day, no matter what I ate. Dr said take an allergy otc. Knocked down the itching for 3-4 days then start right back up. Histimine the bodies response to a problem, was being block but not solving the cause. This went on for 1 yr this spring coughing got worse after a bad cold. couldn't take it any more. I knew something is not right. till 4 weeks ago she started me on benicar at $105 per 30 day. after 2 weeks itching stopped ringing stopped. Right front intestinal pain stopped (Which felt like a kidney stone) Coughing stopped. Only thing left is extreme pain rh chest where last rib is next to esphogus. Feels like a somthing is torn ..May be a hiatal hernia from the hard coughing. non smoker
Posted by Vicki Crouch
I was prescribed lisinopril back in 2011, Feb. I tried for many months to take this medication, but it always made me feel as if I was going to pass out. My blood pressure was high and I had many people tell me that I would get used to it. So I would try again to take it, only to have to stop taking after about a week, because I felt like it was killing me (No joking) I had weird heart palpatations and felt like it was sucking the life out of me. About a year after taking this medication on and off. I started having breathing issues, along with shaking. I just found out that I have an enlarged liver. Before taking this medication my Doctor ran liver panels on me and I was fine. So there no questions as far as I'm concerned where all these issues came from(Lisonopril).
Posted by Carol Allen
Lupin makes this horrible drug lisinopril, enalapril and ramipril are also made from the same thing, i stopped it immediately after only five weeks, got a severe skin reaction. i do not know why my doctor chose to give me this, she knows i am very sensitive to drugs.
today my hands are very swollen burning pain in both hands and arms so bad couldnt sleep.
you can find out what it is made from on line, and if I were anyone i would stop it immediately even if no side effects.
Posted by pat kirkbride
Started with severe swelling and burning of the eyes and neck last october. Saw immunologist in january after having 10 of these episodes, she didn't think it was food allergy but could be reaction to lisinopril, I stopped takng it immediately but have had 4 mild reactions since. I started with what I thought was another mild reaction yesterday but today am badly swollen and burnt around my eyes and neck yet again. Doc says it can take 6 months or so for drug to leave the system. I had taken lisinopril for 18 months without any side effects and it controlled my blood pressure very well. I have been tested for all allergies so I do beleive lisiopril is the cause of these awfull symptoms.
Posted by Joanne Waite
I have only been Lisinopril since January 25, 2013...it is now February 22, 2013. After five days, I could barely get my rings off. Mentioned this to my doctor, but no response was given. Since last week I have felt very fatigued and even felt like I could sleep while at work! Still feel pretty tired and have not been able to get my rings back on -- never had that issue before. It seems that my knuckles have swollen -- scary. Will that go away when I stop taking the Lisinopril? My doctor has finally said these could be side effects and I have made a follow-up visit with her.
Posted by Kc
All this happens I'm in the hospital right now:/
Posted by Sara
Ive been taking lisinopril for 2 years now with my high blood pressure (for a twenty year old) last night my lip started swelling up. I thought it was a cold sore or something at first until I woke up this morning with my upper lip twice as swollen! Immediately I went to my doctor who took me off it and prescribed me prednisone for the swelling. I've taken one and already my lip is back to normal. I have been getting hives the past couple of weeks but didn't think any thing of it because the weather has been so cold and every once in awhile my knuckles And palms would swell. I'm glad I've been taken off and luckily in time before my throat swelled up. My doctor said these side effects can happen randomly no matter how long youve been taking lisinopril. I was only on 10mg.
Posted by Nicole
Ive been on Lisinopril/HCL and then plain Lisinopril for a period of about two years for high blood pressure. I had a gap in my health insurance when I moved, so I stopped taking it for about two months. When I got new health insurance, my doctor called in my same prescription, and I started taking it. About three weeks later one night, my top lip became swollen to three times normal size during a phone call. I thought it was a food allergy, and took a benadryl. But the next morning it was still swollen. I went to emergency and as soon as I walked in, the triage nurse told me, "Oh its the Lisinopril."
Of course I had taken one that morning, so they gave me steroids and a digestive aid, observed me till my lip went down. They sent me home with a script for HCTZ. Im continuing to walk and yoga to keep my blood pressure down. But why is this drug still on the market if it can close your throat and kill you?
Posted by Michele Andrew
I have been on Lisnopril/HCTZ for a number of years but this AM awoke with left side of my face swollen - lips, cheecks and lower eye. I went to work ( I work in a hospital) and our dr. on call said it was angioedema from lisinopril. Contacted my PCP and he changed me immediately to a calcium channel blocker and told me not to take NSAIDs. I took Claritan and benedryl and now, after 9 hours, my face is nearly back to normal. Maybe my aches and pains ( for which I took the NSAIDs ) are part of the lisinopril problem.
Posted by R. J. HUTZENBUEHLER
WELL I'VE BEEN TAKING IT QUITE A WHILE, NEVER THOUGHT ALL THE JOINT PAIN AND SWEELING WAS BEING CAUSED BY MY MEDS. DOCTOR PUT ME ON AN ANTI-INFLAMATORY MED ALSO.
Posted by Anita Clark
I was on Lisinopril 20mg for over a year. I was seeing the doctor that prescribed it, and voiced complaints that my hair was falling out, I was extremely fatigued, my joints ached, and I felt like my mind was in a fog. She was unconcerned.
One morning I woke up with my left eyelid swollen, and both of my hands swollen so bad I could not go to work. I ached so bad! I had my daughter-in-law drive me to my doctors office because my hands were too swollen and in pain. My doctor looked at me and said she had no idea what the problem was. She told me to put ice on my hands.
I was angry and saw a different doctor a few days later. He immediately took me off the Lisinopril, and with in a couple of days, I saw a tremendous difference! I still have trouble will over all pain, especially in my joints. My (new) doctor has run every test in the books and can not discover the cause of my pain.
Recently, I have begun to wonder if it could be permanent damage, caused by Lisinopril. If anyone else has had this problem, and can help me, I would be more grateful than you could ever imagine.
Posted by Stanley E. Bryant Sr.
I have been on Lisinopril for about 3 years and I just experienced a bad reaction of this medicine while at work. While at work one of my co-workers told me that my lips look like they are swelling , I thought he was trying to be funny until I saw the look on his face. I than took a picture of my lips with my cell phone and saw that my top and bottom lips was so big I went to the ER at the hospital. The first thing the doctor ask me was I on any high blood pressure medicine and what was it, I told him that it was Lisinopril and he told me to stop taking it wright now, do not take anymore of that medicine because that's what causing the swelling. The doctor than told me that I was lucky it didn't cut off my air way.
Posted by linda a avery
i have been on lisinopril for approximately eight to ten years & just experienced a new onset of angioedema involving the bottom lip. i was treated at kaiser (antioch ca) facility & released, prescribed prednisone 50mg for a five day period. should i expect further/additional complications as a result of this new onset of angioedema. i have been taken off lisinopril put can this reoccur. i await your response. thank you,
Posted by Jerry Flanagan
My husband has been on Lisinopril for several years, currenlty reduced to 10mg. should we be concerned.
Posted by Tom P.
I, too, have been taking lisinopril or several years. Where do I stand with this issue?
Posted by Mary LeRose
I have been taking 20 ml of lisinopril for many many years, do I need to be concerned?
Posted by Cheryl Jennings
Oh Great! I have been on 40 mg of Lisinopril once a day for YEARS!!!! I am fortunate to have a Dr who listens to my desire to get off of as many pharmaceuticals as I can, because they ALL have side effects!! THANKS FDA!!!! I took my medical care back into my own hands when Instarted taking a food supplement called ZIJA made from every part of the tree, Moringa Oleifera. I have lost 130 pounds & have gotten off of Advair 500/50, Albuterol, Flovent, Flonase, Singulair & Actos. I feel like a different person now, when I can get off the rest of my meds, I am sure I will feel 100% better.
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