Lawyers and Settlements
What are you looking for?
Home Page >> News Articles >> More Research Needed on Depakote

More Research Needed on Depakote

. By
Chicago, IL: With studies suggesting a risk of Depakote side effects when women who are pregnant take the medication, the US Food and Drug Administration (FDA) has issued its own warnings about the use of Depakote while pregnant. Because Depakote (known generically as valproic acid) is used as an anti-convulsant and a mood stabilizer, women of child-bearing age may have no choice but to use the medication if they do not tolerate other anti-convulsant medications, and run the risk of Depakote birth defects.

More Research Needed on DepakoteSpecifically of concern are a reported risk of decreased IQ and a risk of autism that have been linked to the use of valproic acid. “The emerging clinical evidence showing a link between VPA [valproic acid] exposure and both cognitive function and risk of autism brings to the forefront the importance of understanding how VPA exposure influences neurodevelopment,” researchers wrote in a study published in Neurotoxicology and Teratology (found online at www.ncbi.nlm.nih.gov; 2/8/13).

They went on to note that behavioral studies on rats and mice show that exposure to valproic acid increases autistic-like behaviors in offspring. Those behaviors include repetitive behaviors, communication problems and social behavior issues. Studies on humans indicate similar findings, but more research is needed.

A study published online in The Lancet Neurology (1/23/13), for example, found that children six years of age who were exposed to Depakote prior to birth had an average IQ of 97, compared with children not exposed to Depakote who had an average IQ of 105. This finding was reportedly dose dependent, meaning the higher the dose that the children were exposed to, the greater the impact on IQ. Among the cognitive tests included in the study were memory and verbal abilities.

The findings led researchers to conclude that valproate usage by a pregnant mother has a “significant negative effect” on the child’s IQ. Furthermore, this effect lasts well into childhood.

In June 2011, the FDA issued a warning about fetal exposure to Depakote and a risk of cognitive problems. The warning noted that children exposed to valproate or related products prior to birth tend to have lower IQ and cognitive test scores than children exposed to other anti-seizure medications. Among the cognitive tests included in the FDA’s warning were abstract reasoning and problem solving.

Depakote is approved to treat seizures, bipolar disorder and migraine headaches.

Depakote Birth Defect Legal Help

If you or a loved one have suffered losses in this case, please click the link below and your complaint will be sent to a drugs & medical lawyer who may evaluate your Depakote Birth Defect claim at no cost or obligation.
Click here for a free evaluation

READER COMMENTS

Posted by
FLORA HAAS
on
Known side effect of d
Depakote
includes anemia. Yet, some MDs are ignoring this & attributing this side effect in their patients to intestinal cancer. Making side effect of anemia still worse, is another lesser known side effect: anorexia.

It's time some caring, honorable reseachers got back to the drawing board on Depakote. This drug contributed to the death of my adult son, who was subjected to all sorts of testing for GI and other possible cancersthat his inferior primary care doctor believed likely. Doctors to whom my son was referred -- including GI TEAM -- never thought, either, to look at meds + side effects -- until one intelligent doctor - finally - said to end the depakote. Results: patient began eating normally, enjoying food again, gained needed weight.
NAMI -- NATIONAL ASSOCIATION FOR MENTAL ILLNESS NEEDS TO TAKE AN INTELLIGENT LOOK NOT ONLY AT DEPAKOTE BUT ALSO AT SEROQUEL + HEAVILY ADVERTISED ABILIFY -- ON THIS ENTIRE GROUP OF ABOUT A HALF-DOZEN "ATYPICAL" PSYCHIATRIC DRUGS.
SEE VANERBULT MED SCHOOL REPORT ON DEATHS WITH THIS BUNCH OF ATYPICAL PSYCHIATRIC DRUGS, IN NEW ENGLAND JOURNAL OF MEDICINE, IN EARLY 2009.
I am a professional journalist. F.H.

ADD YOUR COMMENT ON THIS STORY

Fields marked * are mandatory. Please read our comment guidelines before posting.

*Name:

Note: Your name will be published with your comment.

*Email Address:

Your email will only be used if a response is needed.

*Your Comment:


Click to learn more about LawyersandSettlements.com


Legal Services:

Facebook



 
FAQ | TOS | Privacy | Disclaimer | About Us | Contact Us | Press | Advertise | Member Login | Jobs | Site Map | View Mobile Website |


Better Business Bureau   CAALA   Best of the Web Approved   Public Justice


This work is licensed under a Creative Commons Attribution-NoDerivs 3.0 Unported License © 2001-2014 Online Legal Media. All rights reserved.